scholarly journals The Significance of the Ki-67 Labeling Index, the Expression of c-kit, p53, and bcl-2, and the Apoptotic Count on the Prognosis of Gastrointestinal Stromal Tumor

10.5772/32356 ◽  
2012 ◽  
Author(s):  
Keishiro Aoyagi ◽  
Kikuo Kouhuji ◽  
Kazuo Shirouzu
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Stromal Tumor ◽  
Labeling Index ◽  
Ki 67

scholarly journals Evaluation of malignancy using Ki-67 labeling index for gastric stromal tumor

2003 ◽  
Vol 6 (3) ◽  
pp. 168-172 ◽  
Author(s):  
Yoshihide Nagasako ◽  
Kazuhito Misawa ◽  
Shigechika Kohashi ◽  
Kimiharu Hasegawa ◽  
Yumi Okawa ◽  
...  
Keyword(s):  
Stromal Tumor ◽  
Labeling Index ◽  
Ki 67 ◽  
Gastric Stromal Tumor

scholarly journals Prognostic Significance of Ki-67 Expression in Patients Undergoing Surgical Resection for Gastrointestinal Stromal Tumor

2014 ◽  
Vol 64 (2) ◽  
pp. 87 ◽  
Author(s):  
Seong Yeon Jeong ◽  
Won Wo Park ◽  
You Sun Kim ◽  
Young Il Park ◽  
Seung Hyup Kim ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Surgical Resection ◽  
Prognostic Significance ◽  
Stromal Tumor ◽  
Ki 67

scholarly journals Image analysis is an excellent tool for quantifying Ki-67 to predict the prognosis of gastrointestinal stromal tumor patients

2017 ◽  
Vol 68 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Shintaro Sugita ◽  
Hiroshi Hirano ◽  
Yutaka Hatanaka ◽  
Hiromi Fujita ◽  
Terufumi Kubo ◽  
...  
Keyword(s):  
Image Analysis ◽  
Gastrointestinal Stromal Tumor ◽  
Stromal Tumor ◽  
Tumor Patients ◽  
Ki 67 ◽  
Excellent Tool

scholarly journals Ki-67 Labeling Index can be used as a Prognostic Marker in Gastrointestinal Stromal Tumor: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 31 (2) ◽  
pp. 204-210 ◽  
Author(s):  
Jung-Soo Pyo ◽  
Guhyun Kang ◽  
Jin Hee Sohn
Keyword(s):  
Systematic Review ◽  
Gastrointestinal Stromal Tumor ◽  
Diagnostic Test ◽  
Tumor Recurrence ◽  
Meta Analysis ◽  
Diagnostic Test Accuracy ◽  
Labeling Index ◽  
Test Accuracy ◽  
Ki 67

Purpose The aim of this study was to investigate the prognostic relevance of the Ki-67 labeling index (LI) in gastrointestinal stromal tumor (GIST) through a systematic review, meta-analysis and diagnostic test accuracy review. Method The study included 1,967 GIST cases from 24 eligible studies. We investigated the correlation between high Ki-67 LI and survival and the proper criteria for high Ki-67 LI. In addition, a diagnostic test accuracy review was conducted to evaluate the predictive role of high Ki-67 LI for higher risk of tumor recurrence. Results A high Ki-67 LI was significantly correlated with worse disease-free survival (DFS) (hazard ratio [HR] 3.658, 95% confidence interval [CI] 2.687-4.979, p<0.001) and overall survival (OS) (HR 3.730, 95% CI 2.819-4.936, p<0.001). With regard to DFS and OS, the subgroup with a cutoff value of >4% for high Ki-67 LI had a higher HR than the subgroup with a ≤4% cutoff. In the diagnostic test accuracy review, a high Ki-67 LI was significantly correlated with higher risk of tumor recurrence (pooled sensitivity = 0.44, pooled specificity = 0.87, area under the curve on the summary receiver operating characteristic curve = 0.656). Conclusions Our results showed that a high Ki-67 LI was significantly correlated with worse prognosis and higher risk of tumor recurrence in GIST. Further prospective studies of the prognostic role of Ki-67 LI are necessary prior to application in clinical practice.

scholarly journals Analysis of the amount of tissue sample necessary for mitotic count and Ki-67 index in gastrointestinal stromal tumor sampling

2014 ◽  
Vol 33 (1) ◽  
pp. 215-222 ◽  
Author(s):  
HIDEKI KOBARA ◽  
HIROHITO MORI ◽  
KAZI RAFIQ ◽  
SHINTARO FUJIHARA ◽  
NORIKO NISHIYAMA ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Tissue Sample ◽  
Mitotic Count ◽  
Stromal Tumor ◽  
Ki 67 ◽  
Tumor Sampling

scholarly journals Gastrointestinal Stromal Tumor and Ki-67 as a Prognostic Indicator

Cureus ◽  
2022 ◽  
Author(s):  
Kevin J Kadado ◽  
Oaklee L Abernathy ◽  
William J Salyers ◽  
K. James Kallail
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Prognostic Indicator ◽  
Stromal Tumor ◽  
Ki 67
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