scholarly journals Assisted Reproductive Technology and Congenital Malformations

10.5772/32304 ◽  
2012 ◽  
Author(s):  
Johanna A. ◽  
Alastair G.
Keyword(s):  
Assisted Reproductive Technology ◽  
Congenital Malformations ◽  
Reproductive Technology

Congenital malformations associated with assisted reproductive technology: A California statewide analysis

2013 ◽  
Vol 48 (6) ◽  
pp. 1218-1224 ◽  
Author(s):  
Lorraine I. Kelley-Quon ◽  
Chi-Hong Tseng ◽  
Carla Janzen ◽  
Stephen B. Shew
Keyword(s):  
Assisted Reproductive Technology ◽  
Congenital Malformations ◽  
Reproductive Technology

scholarly journals Congenital malformations and minor anomalies in newborns depending on the type of resolved infertility and health of the parents

2021 ◽  
pp. 22-28
Author(s):  
M. K. Soboleva ◽  
D. A. Кinsht
Keyword(s):  
Assisted Reproductive Technology ◽  
Congenital Malformations ◽  
Medical Center ◽  
Reproductive Technologies ◽  
Reproductive Technology ◽  
Blastocyst Stage ◽  
Fertility Treatment ◽  
Complete Continuity ◽  
History Of ◽  
Minor Anomalies

Introduction. The use of  sisted reproductive technologies has had sufficient experience to reduce the risks associated with the technologies themselves. But pediatricians remain concerned about the health of children born from induced pregnancies because of the influence of the parents’ initial health on perinatal outcomes. Congenital malformations remain socially significant, the risk of which may be higher for children from induced pregnancy.Objective: to evaluate the effect of initial parental health and the methods of assisted reproductive technology used on the formation of congenital malformations and minor anomalies in children from singleton induced pregnancies.Materials and Methods. A retrospective cohort study was conducted using data on live-born children from singleton induced pregnancy born at the Avicenna Medical Center (Novosibirsk) over the period from 2007 to 2017 (n = 409). The reproductive, somatic, and infectious history of the parents and the methods of assisted reproductive technology used were assessed. Parental fertility treatment up to childbirth was performed in the same center, which ensured complete continuity of follow-up. Differences between the groups of children from SIP with and without congenital anomalies were determined using Pearson’s chi-squared test.Results and discussion. We found that children with congenital malformations and minor anomalies were more often born as a result of subsequent pregnancies; thawed embryos transferred at the blastocyst stage were used in assisted reproductive technology programs (p < 0.05); exacerbations of herpes type 2 infection were diagnosed during the current pregnancy (p < 0.05). In the group of children with only CM, the parents had a longer history of infertility (8.3 ± 1.2) years; pregnancy was achieved by transferring fresh embryos at the blastocyst stage (in 68.2% of cases). In the group of children without congenital malformations and minor anomalies, the maternal infectious history was more severe: there were significantly more frequent cases of urogenital infections (p < 0.05) and exacerbations of herpes simplex virus type 1 during pregnancy (p < 0.05).Conclusion. A set of measures aimed at an earlier solution of the infertility problem is necessary for the primary prevention of congenital abnormalities associated with the age and duration of parental infertility.

scholarly journals Multiple Congenital Anomalies after Assisted Reproductive Technology in Japan (between 2004 and 2009)

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Syuichi Ooki
Keyword(s):  
Assisted Reproductive Technology ◽  
Congenital Anomalies ◽  
Congenital Malformations ◽  
Circulatory System ◽  
Reproductive Technology ◽  
Computer Algorithms ◽  
Multiple Congenital Anomalies ◽  
Major Organ ◽  
Icd 10 ◽  
Major Organ System

Multiple congenital anomalies (MCAs) are defined as two or more unrelated major structural malformations that cannot be explained by an underlying syndrome or sequence. The percentage and combination patterns of MCAs were analyzed using the European surveillance of congenital anomalies computer algorithms for nationwide data on congenital anomalies after assisted reproductive technology between 2004 and 2009 in Japan. There were a total of 177,548 pregnancies and 124,846 live births. About 7% (96/1,324) were MCAs. Although most maternal/neonatal outcomes between the isolated cases group and the MCAs group were similar, higher early neonatal death rate was observed in the MCAs group than in the isolated cases group (9.8% versus 3.7%, resp.). Regarding the major organ system subcategory in ICD-10, the rate of MCAs was around 30% in “congenital malformations of eye, ear, face, and neck,” “congenital malformations of the respiratory system,” and “congenital malformations of genital organs.” On the other hand, the rate of MCAs was less than 10% in “congenital malformations of the circulatory system.” The combination patterns of diseases were widely varied. Of them, two or three diseases of the circulatory system, the digestive system, and the musculoskeletal system tended to co-occur in the same individuals.

scholarly journals Trends over time in congenital malformations in live-born children conceived after assisted reproductive technology

2018 ◽  
Vol 97 (7) ◽  
pp. 816-823 ◽  
Author(s):  
Anna-Karina A. Henningsen ◽  
Christina Bergh ◽  
Rolv Skjaerven ◽  
Aila Tiitinen ◽  
Ulla-Britt Wennerholm ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Congenital Malformations ◽  
Reproductive Technology ◽  
Trends Over Time ◽  
Over Time

Assisted reproductive technology and risk of congenital malformations: a meta-analysis based on cohort studies

2015 ◽  
Vol 292 (4) ◽  
pp. 777-798 ◽  
Author(s):  
Jiabi Qin ◽  
Xiaoqi Sheng ◽  
Hua Wang ◽  
Desheng Liang ◽  
Hongzhuan Tan ◽  
...  
Keyword(s):  
Cohort Studies ◽  
Assisted Reproductive Technology ◽  
Congenital Malformations ◽  
Meta Analysis ◽  
Reproductive Technology
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