scholarly journals Crosstalk Between the Immune and Central Nervous Systems with Special Reference to Drug Development

10.5772/29057 ◽  
2011 ◽  
Author(s):  
Takekazu Kubo ◽  
Shigeru Tokita ◽  
Toshihide Yamashit
Keyword(s):  
Drug Development ◽  
Special Reference ◽  
Nervous Systems ◽  
Central Nervous Systems

The Inter-reaction of the Endocrine, Sympathetic and Central Nervous Systems in Organismal Toxæmia, with Special Reference to Emotional Disturbance

1923 ◽  
Vol 69 (284) ◽  
pp. 45-49
Author(s):  
David Orr
Keyword(s):  
Nervous System ◽  
Special Reference ◽  
Annual Meeting ◽  
Emotional Disturbance ◽  
Close Association ◽  
Nervous Systems ◽  
Central Nervous Systems

When approached by the President of the Medico-Psychological Association to give a short address at the Annual Meeting I chose the above title. On reflection, however, I find it is somewhat over- ambitious and cannot be dealt with in the time at our disposal. It would be better, perhaps, if I endeavoured to place before you some broad principles relative to the close association between neuropathology and psychiatry, and indicate the data in support of the view that anatomically, physiologically, and pathologically the entire nervous system must be regarded, along with its endocrinic appendages, as a unit, each of whose component parts reacts upon the others.

GABA-, histamine-, and FMRFamide-immunoreactivity in the visual, vestibular and central nervous systems ofHermissenda crassicornis

2017 ◽  
Vol 525 (16) ◽  
pp. 3514-3528 ◽  
Author(s):  
Marissa P. Webber ◽  
James W. S. Thomson ◽  
Johnny Buckland-Nicks ◽  
Roger P. Croll ◽  
Russell C. Wyeth
Keyword(s):  
Nervous Systems ◽  
Central Nervous Systems

reaper is required for neuroblast apoptosis during Drosophila development

Development ◽  
2002 ◽  
Vol 129 (6) ◽  
pp. 1467-1476 ◽  
Author(s):  
Christian Peterson ◽  
Ginger E. Carney ◽  
Barbara J. Taylor ◽  
Kristin White
Keyword(s):  
Hormone Receptor ◽  
Receptor Complex ◽  
Developmentally Regulated ◽  
Drosophila Development ◽  
Nervous Systems ◽  
Limited Role ◽  
Central Nervous Systems

Developmentally regulated apoptosis in Drosophila requires the activity of the reaper (rpr), grim and head involution defective (hid) genes. The expression of these genes is differentially regulated, suggesting that there are distinct requirements for their proapoptotic activity in response to diverse developmental and environmental inputs. To examine this hypothesis, a mutation that removes the rpr gene was generated. In flies that lack rpr function, most developmental apoptosis was unaffected. However, the central nervous systems of rpr null flies were very enlarged. This was due to the inappropriate survival of both larval neurons and neuroblasts. Importantly, neuroblasts rescued from apoptosis remained functional, continuing to proliferate and generating many extra neurons. Males mutant for rpr exhibited behavioral defects resulting in sterility. Although both the ecdysone hormone receptor complex and p53 directly regulate rpr transcription, rpr was found to play a limited role in inducing apoptosis in response to either of these signals.

Some Modifications of Holmes's Silver Method for Insect Central Nervous Systems

1961 ◽  
Vol s3-102 (59) ◽  
pp. 413-417
Author(s):  
A. D. BLEST
Keyword(s):  
Silver Nitrate ◽  
Neurosecretory Cells ◽  
Pyridine Derivatives ◽  
Nervous Systems ◽  
Central Nervous Systems ◽  
Pre Treatment

Two main modifications of Holmes's method are described. In both the amount of silver nitrate in the impregnating bath is increased, and larger quantities of higher pyridine derivatives are substituted for pyridine. The preferred method for general purposes employs 2.4% 2:6 lutidine at pH 8.4, and gives a bluish picture with improved selectivity of fibre staining. The use of 1.6% 2:4:6 collidine gives a reddish picture, with highly selective fibre staining, and sharp resolution of neurosecretory cells. Minor modifications of pre-treatment and reduction procedures are also described.

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