scholarly journals Protein Engineering with Non-Natural Amino Acids

10.5772/28719 ◽  
2012 ◽  
Author(s):  
Aijun Wang ◽  
Natalie Winblade ◽  
Marcello Marelli ◽  
Kenneth Grabstei
Keyword(s):  
Amino Acids ◽  
Protein Engineering ◽  
Natural Amino Acids

Four-base codon/anticodon strategy and non-enzymatic aminoacylation for protein engineering with non-natural amino acids

Methods ◽  
2005 ◽  
Vol 36 (3) ◽  
pp. 270-278 ◽  
Author(s):  
Masahiko Sisido ◽  
Keiko Ninomiya ◽  
Takashi Ohtsuki ◽  
Takahiro Hohsaka
Keyword(s):  
Amino Acids ◽  
Protein Engineering ◽  
Natural Amino Acids

Synthesis and characteristics of ethylenediamine-N,N'-di-S-α-isovalerate and isomers of its cobalt(III) complexes

1982 ◽  
Vol 47 (1) ◽  
pp. 210-216 ◽  
Author(s):  
Milan Strašák ◽  
František Bachratý ◽  
Jaroslav Majer
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Electronic Absorption ◽  
Electronic Absorption Spectra ◽  
Chemical Parameters ◽  
Methyl Group ◽  
Nmr Data ◽  
Physico Chemical ◽  
Natural Amino Acids ◽  
C Nmr

The synthesis and physico-chemical parameters are described of a new complexone based on natural amino acids, viz. ethylenediamine-N,N'-di-S-α-isovalerate (SS-EDDIV). 1H- and 13C-NMR data revealed that the methyl group in the substance are not equivalent. The isomers of the cobalt(III) complex with the asymmetric tetradentate SS-EDDIV ligand were prepared and separated; their characteristics are given. The absolute configuration of two of the five theoretically feasible isomers was determined based on their electronic absorption spectra and circular dichroism data.

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