scholarly journals Relationships Among Renal Function, Bone Turnover and Periodontal Disease

10.5772/25709 ◽  
2012 ◽  
Author(s):  
Akihiro Yoshihara ◽  
Lisdrianto Hanindriyo
2004 ◽  
Vol 34 (1) ◽  
pp. 113-118 ◽  
Author(s):  
Glenda Ramalho Barbudo-Selmi ◽  
Marileda Bonafim Carvalho ◽  
André Luis Selmi ◽  
Silvio Emílio Cuevas Martins

The purpose of this study was to evaluate periodontal disease (PD) in dogs with chronic renal failure (CRF) and to compare it to PD in dogs with normal renal function (NRF). Twelve dogs with CRF and 24 dogs with NRF, all presenting dental pocket formation, were compared. In all dogs, serum creatinine, blood urea nitrogen, urine specific gravity and total red and white blood cells were determined. A complete oral examination was also performed including evaluation of bacterial plaque, gingivitis, gingival recession, pocket, calculus, dental mobility, dental loss, and ulcers. These data were used to calculate plaque index (PI), gingival index (GI) and periodontal destruction index (PDI). PD was graded as mild, moderate or severe based on the results. Mild, moderate or severe PD was observed in dogs with NRF, whereas dogs with CRF presented either mild or severe PD. Dogs with NRF showed higher involvement of the maxillary teeth, whereas dogs with CRF showed a higher involvement of the mandibular teeth. Plaque index was significantly higher in dogs with NRF. It was concluded that lesion distribution and periodontal disease progression may be altered in dogs with CRF, and gingival inflammatory response differs in dogs with NRF and CRF regarding to the stage of periodontal disease.


2017 ◽  
Vol 44 (5) ◽  
pp. 484-489 ◽  
Author(s):  
Akihiro Yoshihara ◽  
Noriko Sugita ◽  
Masanori Iwasaki ◽  
Yanming Wang ◽  
Hideo Miyazaki ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Wenjing Ni ◽  
Yue Yuan ◽  
Xiaoqiu Chu ◽  
Guofang Chen ◽  
Xue Han ◽  
...  

ObjectiveTo assess the efficacy and safety of ultrasound-guided microwave ablation (MWA) in the treatment of primary hyperparathyroidism (PHPT), and to investigate whether MWA can improve the bone turnover and renal function.MethodsA total of 20 consecutive PHPT patients with 21 parathyroid lesions treated with MWA in our center from May 2019 to March 2021 were recruited in this study. Serum parathyroid hormone (PTH), calcium and phosphorus levels before MWA and at 20 minutes, 4 hours, 1 day, 3 months, 6 months and 12 months after MWA were measured. Bone turnover biomarkers, renal function and lesion volume with volume reduction rate (VRR) before MWA and at the last follow-up were compared. Any complication related with MWA was evaluated. The technical and clinical success rates of MWA in the treatment of PHPT were calculated. Clinical success was defined as normal serum PTH and calcium without PHPT-associated manifestations at more than 6 months after ablation. Technical success was defined as complete ablation indicated by immediate postoperative contrast-enhanced ultrasound.ResultsThe serum PTH, calcium and phosphorus levels at their respective follow-up time points dropped significantly after MWA (P <0.05). The volume of parathyroid lesions at the final examination was significantly reduced, compared with pre-ablation volume (P <0.001), with a median VRR reaching 89%. The technical and clinical success rates were 100% and 63.6%, respectively. Substantial changes of bone turnover biomarkers were observed before and after MWA (P <0.05), but the differences in renal function were not statistically significant. No major complications were reported in all cases. Pre-MWA serum PTH, lesion volume, maximum diameter of lesion and ablation time were significantly different between patients with successful and failed MWA.ConclusionsPHPT can be effectively and safely treated by ultrasound-guided MWA, as proven by drop in serum PTH and reduction in the volume of parathyroid adenomas. Besides, MWA can impede bone remodeling to suppress hyperparathyroidism in the condition of PHPT.


2016 ◽  
Vol 43 (9) ◽  
pp. 720-726 ◽  
Author(s):  
Akihiro Yoshihara ◽  
Masanori Iwasaki ◽  
Hideo Miyazaki ◽  
Kazutoshi Nakamura

1994 ◽  
Vol 72 (6) ◽  
Author(s):  
K. Mizunashi ◽  
K. Takaya ◽  
H. Sato ◽  
S. Mori ◽  
K. Abe ◽  
...  

2015 ◽  
Vol 18 (3) ◽  
pp. 440
Author(s):  
Kenneth Izuora ◽  
Echezona Ezeanolue ◽  
Guogen Shan ◽  
Michael Neubauer ◽  
Civon Gewelber ◽  
...  

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