Understanding Tuberculosis - New Approaches to Fighting Against Drug Resistance

10.5772/2477 ◽  
2012 ◽  
Author(s):  
Shailesh Kumar Singh ◽  
Arif Mohammed ◽  
Othman A. Alghamdi ◽  
Syed Masood Husain

Author(s):  
Vassilios Avramis ◽  
Robert Biener ◽  
John Holcenberg

Author(s):  
J. R. Bertino ◽  
S. Srimatkandada ◽  
M. D. Carman ◽  
M. Jastreboff ◽  
L. Mehlman ◽  
...  

Parasitology ◽  
2013 ◽  
Vol 140 (12) ◽  
pp. 1534-1546 ◽  
Author(s):  
ROBERT M. GREENBERG

SUMMARYSchistosomes are parasitic flatworms that cause schistosomiasis, a neglected tropical disease that affects hundreds of millions worldwide. Treatment and control of schistosomiasis relies almost entirely on the single drug praziquantel (PZQ), making the prospect of emerging drug resistance particularly worrisome. This review will survey reports of PZQ (and other drug) resistance in schistosomes and other platyhelminths, and explore mechanisms by which drug resistance might develop. Newer genomic and post-genomic strategies that offer the promise of better understanding of how drug resistance might arise in these organisms will be discussed. These approaches could also lead to insights into the mode of action of these drugs and potentially provide markers for monitoring the emergence of resistance.


2016 ◽  
Vol 7 ◽  
Author(s):  
Jose A. Garcia-Salcedo ◽  
Juan D. Unciti-Broceta ◽  
Javier Valverde-Pozo ◽  
Miguel Soriano

2019 ◽  
Vol 42 ◽  
Author(s):  
Karen Bartsch ◽  
David Estes

Abstract In challenging the assumption of autistic social uninterest, Jaswal & Akhtar have opened the door to scrutinizing similar unexamined assumptions embedded in other literatures, such as those on children's typically developing behaviors regarding others’ minds and morals. Extending skeptical analysis to other areas may reveal new approaches for evaluating competing claims regarding social interest in autistic individuals.


Sign in / Sign up

Export Citation Format

Share Document