scholarly journals Lipid Rafts as Master Regulators of Breast Cancer Cell Function

10.5772/21324 ◽  
2011 ◽  
Author(s):  
Irina S. ◽  
Simona Donatello ◽  
Ivan R. ◽  
Ann M.
Keyword(s):  
Breast Cancer ◽  
Lipid Rafts ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cell Function ◽  
Master Regulators

scholarly journals TNF-α promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts

2016 ◽  
Vol 39 (4) ◽  
pp. 353-363 ◽  
Author(s):  
Dominika Wolczyk ◽  
Magdalena Zaremba-Czogalla ◽  
Anita Hryniewicz-Jankowska ◽  
Renata Tabola ◽  
Krzysztof Grabowski ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Migration ◽  
Lipid Rafts ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Migration ◽  
Breast Cancer Cell Migration ◽  
Tnf Α

Low Expression of miR-663a Indicates Poor Prognosis and Promotes Cell Proliferation, Migration, and Invasion in Breast Cancer

2021 ◽  
pp. 1-8
Author(s):  
Gang Wang ◽  
Lei Chen ◽  
Wei Jian ◽  
Lin Fang
Keyword(s):  
Breast Cancer ◽  
Cell Proliferation ◽  
Tumor Suppressor ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cell Function ◽  
Quantitative Polymerase Chain Reaction ◽  
Migration And Invasion ◽  
Cancer Tissue ◽  
Cox Regression Analysis

<b><i>Introduction:</i></b> Breast cancer is one of the most common malignant cancers among women worldwide. MicroRNA-663a (miR-663a) acts as a tumor suppressor gene involved in the development of various cancers. <b><i>Objective:</i></b> The aim of this study was to reveal the clinical significance and biological function of miR-663a in breast cancer. <b><i>Methods:</i></b> The expression of miR-663a in breast cancer tissues and cells was evaluated by reverse transcription-quantitative polymerase chain reaction. Kaplan-Meier survival and Cox regression analysis were performed to evaluate the prognostic significance of miR-663a in breast cancer. CCK-8 and Transwell assays were used to demonstrate the effect of miR-663a on breast cancer cell function. <b><i>Results:</i></b> We confirmed that the expression of miR-663a was significantly downregulated in breast cancer tissue samples and cell lines. Low miR-663a expression was significantly associated with lymph node metastasis, TNM stage, subtypes, and poor survival in breast cancer patients, indicating that miR-663a is an independent prognostic factor for patients with breast cancer. Cell function experiments revealed that low miR-663a expression promoted cell proliferation, migration, and invasion in breast cancer. <b><i>Conclusions:</i></b> All experimental results demonstrated that miR-663a acts as a tumor suppressor that inhibits the proliferation, migration, and invasion of breast cancer cells, and miR-663a may be a prognostic biomarker and therapeutic target for breast cancer.

scholarly journals Sigma-1 Receptors Bind Cholesterol and Remodel Lipid Rafts in Breast Cancer Cell Lines

2007 ◽  
Vol 67 (23) ◽  
pp. 11166-11175 ◽  
Author(s):  
Christopher P. Palmer ◽  
Robert Mahen ◽  
Eva Schnell ◽  
Mustafa B.A. Djamgoz ◽  
Ebru Aydar
Keyword(s):  
Breast Cancer ◽  
Lipid Rafts ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Sigma 1

Direct effect of sevoflurane on breast cancer cell function in vitro

2010 ◽  
Vol 27 ◽  
pp. 1
Author(s):  
P. Ecimovic ◽  
B. McHugh ◽  
D. Murray ◽  
P. Doran ◽  
D. Buggy
Keyword(s):  
Breast Cancer ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Direct Effect ◽  
Cell Function

scholarly journals Effect of anaesthetic technique on oestrogen receptor-negative breast cancer cell function in vitro †

2009 ◽  
Vol 103 (5) ◽  
pp. 685-690 ◽  
Author(s):  
C.A. Deegan ◽  
D. Murray ◽  
P. Doran ◽  
P. Ecimovic ◽  
D.C. Moriarty ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Oestrogen Receptor ◽  
Cell Function ◽  
Anaesthetic Technique

scholarly journals Direct effect of morphine on breast cancer cell function in vitro : role of the NET1 gene

2011 ◽  
Vol 107 (6) ◽  
pp. 916-923 ◽  
Author(s):  
P. Ecimovic ◽  
D. Murray ◽  
P. Doran ◽  
J. McDonald ◽  
D.G. Lambert ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Direct Effect ◽  
Cell Function

Xenon and breast cancer cell function in-vitro

2014 ◽  
Vol 31 ◽  
pp. 160
Author(s):  
S. A. Ash ◽  
G. Valchev ◽  
P. Crowley ◽  
H. G. Gallagher ◽  
D. J. Buggy
Keyword(s):  
Breast Cancer ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cell Function
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