scholarly journals Gene Therapy of Melanoma Using Inactivated Sendai Virus Envelope Vector (HVJ-E) with Intrinsic Anti-Tumor Activities

10.5772/17492 ◽  
2011 ◽  
Author(s):  
Yasufumi Kaneda ◽  
Eiji Kiyohara ◽  
Toshihiro Nakajima ◽  
Toshimitsu Itai
Keyword(s):  
Gene Therapy ◽  
Sendai Virus ◽  
Virus Envelope

Studies of membrane fusion. VI. Mechanism of the membrane fusion and cell swelling stages of Sendai virus-mediated cell fusion

1980 ◽  
Vol 43 (1) ◽  
pp. 103-118
Author(s):  
S. Knutton
Keyword(s):  
Membrane Fusion ◽  
Cell Fusion ◽  
Sendai Virus ◽  
Freeze Fracture ◽  
Viral Envelope ◽  
Cell Swelling ◽  
Fusion Event ◽  
Virus Envelope ◽  
Membrane Rupture ◽  
Membrane Tubules

The membrane fusion and cell swelling stages of Sendai virus-mediated cell-cell fusion have been studied by thin-section and freeze-fracture electron microscopy. Sites of membrane fusion have been detected in human erythrocytes arrested at the membrane fusion stage of cell fusion and in virtually all cases a fused viral envelope or envelope components has been identified thus providing further direct evidence that cell-viral envelope-cell bridge formation is the membrane fusion event in Sendai virus-induced cell fusion. Radial expansion of a single virus bridge connecting 2 cells is sufficient to produce a fused cell. Membrane redistribution which occurs during this cell swelling stage of the fusion process is often accompanied by the formation of a system of membrane tubules in the plane of expansion of the virus bridge. The tubules originate from points of fusion between the bridging virus envelope and the erythrocyte membrane and also expand radially as cells swell. Ultimately membrane rupture occurs and the tubules appear to break down as small vesicles. When previously observed in cross-sectioned cells these membrane tubules were interpreted as sites of direct membrane fusion. The present study indicates that this interpretation is incorrect and shows that the tubules are generated subsequent to membrane fusion when 2 cells connected by a virus bridge are induced to swell. A mechanism to explain the formation of this system of membrane tubules is proposed.

Kinetics of Sendai virus envelope fusion with erythrocyte membranes and virus-induced hemolysis

Biochemistry ◽  
1979 ◽  
Vol 18 (23) ◽  
pp. 5088-5095 ◽  
Author(s):  
Douglas S. Lyles ◽  
Frank R. Landsberger
Keyword(s):  
Sendai Virus ◽  
Erythrocyte Membranes ◽  
Virus Envelope ◽  
Kinetics Of

Effect of membrane potential of fusion of sendai virus envelope with chick erythrocyte membrane and on virus-induced hemolysis

1988 ◽  
Vol 106 (6) ◽  
pp. 1748-1751
Author(s):  
V. A. Slepushkin ◽  
V. M. Chumakov ◽  
A. �. Kalmanson ◽  
S. M. Marchenko ◽  
A. G. Bukrinskaya
Keyword(s):  
Membrane Potential ◽  
Erythrocyte Membrane ◽  
Sendai Virus ◽  
Virus Envelope

scholarly journals Gene Therapy for Tracheal Stenosis Using Sendai Virus Vector

2015 ◽  
Vol 27 (2) ◽  
pp. 51-58
Author(s):  
Daisuke Mizokami ◽  
Koji Araki ◽  
Akihiro Shiotani
Keyword(s):  
Gene Therapy ◽  
Tracheal Stenosis ◽  
Sendai Virus ◽  
Virus Vector

W1862 Proteoliposomes Containing Sendai Virus F-Glycoprotein for Hepatocyte-Targeted Gene Therapy of the Gunn Rat Model of Crigler-Najjar Syndrome Type 1

2008 ◽  
Vol 134 (4) ◽  
pp. A-840 ◽  
Author(s):  
Xia Wang ◽  
Debi P. Sarkar ◽  
Prashant Mani ◽  
Clifford J. Steer ◽  
Betsy T. Kren ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Rat Model ◽  
Sendai Virus ◽  
Syndrome Type ◽  
Gunn Rat ◽  
Targeted Gene Therapy

Interactions of human lymphoblasts with targeted vesicles containing Sendai virus envelope proteins

1989 ◽  
Vol 185 (1) ◽  
pp. 122-131 ◽  
Author(s):  
O. Sechoy ◽  
M. Vidal ◽  
J.R. Philippot ◽  
A. Bienvenue
Keyword(s):  
Sendai Virus ◽  
Envelope Proteins ◽  
Virus Envelope
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