scholarly journals The Role of 3D Ultrasound in Assessment of Endometrial Receptivity and Follicular Vascularity to Predict the Quality Oocyte

Author(s):  
T. Zackova ◽  
I.Y. Jarvela ◽  
T. Mardesic
2010 ◽  
Vol 1 (1) ◽  
pp. 19-24
Author(s):  
Chaitanya B Nagori

ABSTRACT Background The assessment of the endometrial receptivity at the time of human chorionic gonadotrophin (hCG) is one of the key factors for success of all ART procedures. Aim To assess, if 3D and 3D power Doppler assessment of endometrial receptivity before giving hCG, helps improving pregnancy rates in superovulation with IUI cycles. Settings and Design A prospective randomized study of 2500 cycles of IUI was done over a period of twelve months for pre-hCG endometrial assessment. Method Endometrial assessment was done on Voluson 730 Expert, (Wipro GE) using transvaginal multifrequency volume probe 5 to 9 MHz. When follicles and endometrium were considered mature by 2D US and color Doppler, 3D and 3D power Doppler assessment of the endometrium was done before giving hCG. These values were evaluated for conception and nonconception groups. Results Conception rates were higher, when endometrial volume was between 3 and 7 cc. In our study, we have found endometrial FI > 20 and endometrial VFI > 40 as most optimum. Conclusions 3D ultrasound is accurate for volume assessment of endometrium. 3D and 3D PD, when used with 2D US and color Doppler for pre-hCG endometrial assessment, it would definitely improve implantation rates in IUI cycles.


Author(s):  
CB Nagori

ABSTRACT Assessment of the follicular maturity and endometrial receptivity and the time of hCG is one of the key factors for success of all ART procedures. Maturation of the follicle and the endometrium, ovulation and leutinization is a process of multiple biochemical, morphological and vascular changes. The vascular changes are reflection of the biochemical changes and can be studied by color Doppler. 3D ultrasound gives a better assessment of the follicular and endometrial size, that is the anatomical maturity, than 2D ultrasound and 3D power Doppler gives not only qualitative but also quantitative idea of global vascularity, that is the reflection of functional/physiological maturity. Follicular vascularity distribution and flow indices can be better parameters of follicular quality and can be more reliable parameters to decide the time of hCG and IUI. Endometrial assessment can be more meaningful if its morphology is studied more in detail along with abundance of its vascularity as well as flow indices. Thus, deciding correct time of hCG can improve conception rates in ART cycles. How to cite this article Panchal S, Nagori CB. Follicular Monitoring. Donald School J Ultrasound Obstet Gynecol 2012; 6(3):300-312.


Author(s):  
Daniela Menichini ◽  
Gianpiero Forte ◽  
Beatrice Orrù ◽  
Giuseppe Gullo ◽  
Vittorio Unfer ◽  
...  

Abstract. Vitamin D is a secosteroid hormone that plays a pivotal role in several metabolic and reproductive pathways in humans. Increasing evidence supports the role of vitamin D deficiency in metabolic disturbances and infertility in women with polycystic ovary syndrome (PCOS). Indeed, supplementation with vitamin D seems to have a beneficial role on insulin resistance and endometrial receptivity. On the other hand, exceedingly high levels of vitamin D appear to play a detrimental role on oocytes development and embryo quality. In the current review, we summarize the available evidence about the topic, aiming to suggest the best supplementation strategy in women with PCOS or, more generally, in those with metabolic disturbances and infertility. Based on the retrieved data, vitamin D seems to have a beneficial role on IR, insulin sensitivity and endometrial receptivity, but high levels and incorrect timing of administration seem to have a detrimental role on oocytes development and embryo quality. Therefore, we encourage a low dose supplementation (400–800 IU/day) particularly in vitamin D deficient women that present metabolic disturbances like PCOS. As far as the reproductive health, we advise vitamin D supplementation in selected populations, only during specific moments of the ovarian cycle, to support the luteal phase. However, ambiguities about dosage and timing of the supplementation still emerge from the clinical studies published to date and further studies are required.


Author(s):  
J. M. Puente ◽  
A. Fabris ◽  
J. Patel ◽  
A. Patel ◽  
M. Cerrillo ◽  
...  

2020 ◽  
Vol 8 (4) ◽  
pp. 55-55
Author(s):  
Arvind Burjoo ◽  
Xingping Zhao ◽  
Lingxiao Zou ◽  
Xinyi Liu ◽  
Lei Lei ◽  
...  

Antioxidants ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 957
Author(s):  
Seungjin Noh ◽  
Ara Go ◽  
Da Bin Kim ◽  
Minjeong Park ◽  
Hee Won Jeon ◽  
...  

Infertility, a couple’s inability to conceive after one year of unprotected regular intercourse, is an important issue in the world. The use of natural products in the treatment of infertility has been considered as a possible alternative to conventional therapies. The present study aimed to investigate the effects and the mechanisms of various natural products on infertility. We collected articles regarding infertility and natural products using the research databases PubMed and Google Scholar. Several natural products possess antioxidant properties and androgenic activities on productive factors and hormones. Antioxidants are the first defense barrier against free radicals produced by oxidative stress (OS). They remove reactive oxygen stress (ROS), reducing insulin resistance, total cholesterol, fat accumulation, and cancer growth. Moreover, various natural products increase endometrial receptivity and fertility ability showing androgenic activities on productive factors and hormones. For example, Angelica keiskei powder and Astragalus mongholicus extract showed anti-infertility efficacies in males and females, respectively. On the other hand, adverse effects and acute toxicity of natural products were also reported. Tripterygium glycoside decreased fertility ability both in males and females. Results indicate that management of infertility with natural products could be beneficial with further clinical trials to evaluate the safety and effect.


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