scholarly journals EP32.07: The role of multiple indicators measured by ultrasound in the prediction of endometrial receptivity during FET cycles

2019 ◽  
Vol 54 (S1) ◽  
pp. 433-433
Author(s):  
T. Hu ◽  
A. Zhu ◽  
J. Yu ◽  
J. Qian ◽  
Y. Jin ◽  
...  
Keyword(s):  
Endometrial Receptivity ◽  
Multiple Indicators

The role of vitamin D in metabolic and reproductive disturbances of polycystic ovary syndrome: A narrative mini-review

2020 ◽  
pp. 1-8
Author(s):  
Daniela Menichini ◽  
Gianpiero Forte ◽  
Beatrice Orrù ◽  
Giuseppe Gullo ◽  
Vittorio Unfer ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Embryo Quality ◽  
Polycystic Ovary ◽  
Vitamin D Supplementation ◽  
Endometrial Receptivity ◽  
Metabolic Disturbances ◽  
Ovary Syndrome ◽  
Beneficial Role

Abstract. Vitamin D is a secosteroid hormone that plays a pivotal role in several metabolic and reproductive pathways in humans. Increasing evidence supports the role of vitamin D deficiency in metabolic disturbances and infertility in women with polycystic ovary syndrome (PCOS). Indeed, supplementation with vitamin D seems to have a beneficial role on insulin resistance and endometrial receptivity. On the other hand, exceedingly high levels of vitamin D appear to play a detrimental role on oocytes development and embryo quality. In the current review, we summarize the available evidence about the topic, aiming to suggest the best supplementation strategy in women with PCOS or, more generally, in those with metabolic disturbances and infertility. Based on the retrieved data, vitamin D seems to have a beneficial role on IR, insulin sensitivity and endometrial receptivity, but high levels and incorrect timing of administration seem to have a detrimental role on oocytes development and embryo quality. Therefore, we encourage a low dose supplementation (400–800 IU/day) particularly in vitamin D deficient women that present metabolic disturbances like PCOS. As far as the reproductive health, we advise vitamin D supplementation in selected populations, only during specific moments of the ovarian cycle, to support the luteal phase. However, ambiguities about dosage and timing of the supplementation still emerge from the clinical studies published to date and further studies are required.

scholarly journals Role of Antioxidant Natural Products in Management of Infertility: A Review of Their Medicinal Potential

Antioxidants ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 957
Author(s):  
Seungjin Noh ◽  
Ara Go ◽  
Da Bin Kim ◽  
Minjeong Park ◽  
Hee Won Jeon ◽  
...  
Keyword(s):  
Natural Products ◽  
Antioxidant Properties ◽  
Endometrial Receptivity ◽  
Cancer Growth ◽  
Oxygen Stress ◽  
The World ◽  
Angelica Keiskei ◽  
Males And Females ◽  
One Year

Infertility, a couple’s inability to conceive after one year of unprotected regular intercourse, is an important issue in the world. The use of natural products in the treatment of infertility has been considered as a possible alternative to conventional therapies. The present study aimed to investigate the effects and the mechanisms of various natural products on infertility. We collected articles regarding infertility and natural products using the research databases PubMed and Google Scholar. Several natural products possess antioxidant properties and androgenic activities on productive factors and hormones. Antioxidants are the first defense barrier against free radicals produced by oxidative stress (OS). They remove reactive oxygen stress (ROS), reducing insulin resistance, total cholesterol, fat accumulation, and cancer growth. Moreover, various natural products increase endometrial receptivity and fertility ability showing androgenic activities on productive factors and hormones. For example, Angelica keiskei powder and Astragalus mongholicus extract showed anti-infertility efficacies in males and females, respectively. On the other hand, adverse effects and acute toxicity of natural products were also reported. Tripterygium glycoside decreased fertility ability both in males and females. Results indicate that management of infertility with natural products could be beneficial with further clinical trials to evaluate the safety and effect.

3D and 4D studies from human reproduction to perinatal medicine

2017 ◽  
Vol 45 (6) ◽  
Author(s):  
Sonal Panchal ◽  
Asim Kurjak ◽  
Chaitanya Nagori
Keyword(s):  
Prenatal Diagnosis ◽  
Congenital Malformations ◽  
Three Dimensional ◽  
Endometrial Receptivity ◽  
Human Reproduction ◽  
Fallopian Tubes ◽  
Perinatal Medicine ◽  
Tubal Patency ◽  
Pretreatment Assessment

AbstractThree-dimensional ultrasound (3D US) is a modality of choice for prenatal diagnosis of congenital malformations. But 3D-four-dimensional US(4D US) is of utmost importance also to achieve pregnancy. 3D US plays an important role for diagnosis of PCO, to assess ovarian reserve and response and thus to decide optimum stimulation protocols. It adds to the information on follicular maturity and endometrial receptivity, thus improving the chances to achieve pregnancy for patients under treatment for fertility. 3D hystero-contrast-salpingography (HyCoSy) has also proved itself to be one of the best modalities for assessment of tubal patency. In this article, the role of 3D and 4D US is discussed for the following. I. Pretreatment assessment of the females desiring fertility which includes assessment of uterus and fallopian tubes. II. Monitoring of infertile females undergoing treatment. III. Assessment of very early pregnancy – especially in abnormal locations.

scholarly journals Uterine fibroids and effiency of in vitro fertilization programs

2016 ◽  
Vol 65 (6) ◽  
pp. 79-87 ◽  
Author(s):  
Lyailya Kh Dzhemlikhanova ◽  
Dariko A Niauri ◽  
Zarina K Abdulkadyrova
Keyword(s):  
In Vitro Fertilization ◽  
Uterine Fibroids ◽  
Endometrial Receptivity ◽  
Female Infertility ◽  
Uterine Myoma ◽  
Vitro Fertilization ◽  
Etiologic Role

The aim of this review is to estimate etiologic role of uterine fibroids in female infertility; it based on the results of current studies of infertility in various cases of fibroids (submucous, intramural and subserous). In article was analyzed the efficiency of the treatment of infertility in women with uterine myoma in IVF programs.Conclusion: a detailed study of endometrial receptivity in women with uterine fibroids is necessary to for personalized strategy in patients with uterine fibroids (myoma) and infertility.

scholarly journals The role of the endometrial receptivity array (ERA) in patients who have failed euploid embryo transfers

2018 ◽  
Vol 35 (4) ◽  
pp. 683-692 ◽  
Author(s):  
J Tan ◽  
A Kan ◽  
J Hitkari ◽  
B Taylor ◽  
N Tallon ◽  
...  
Keyword(s):  
Endometrial Receptivity ◽  
Euploid Embryo

Chronic endometritis in women with endometriosis-associated infertility

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (3) ◽  
pp. 15-20
Author(s):  
Mekan R. Orazov ◽  
Victor E. Radzinsky ◽  
Snezhana V. Volkova ◽  
Marina B. Khamoshina ◽  
Ludmila M. Mikhaleva ◽  
...  
Keyword(s):  
Immune Response ◽  
Bacterial Contamination ◽  
Abdominal Cavity ◽  
Reproductive Function ◽  
Endometrial Receptivity ◽  
Reproductive Disorders ◽  
Chronic Endometritis ◽  
Common Features ◽  
Adaptation Mechanisms

The article highlights modern ideas about the role of the endometrium in the genesis of reproductive failures. A crucial place of chronic endometritis in the structure of the endometrial infertility factor in endometriosis is noted. Given the frequent association of chronic endometritis and endometriosis, common features of these diseases have been identified. The characteristic of endometrial microbiota in infertility, chronic endometritis and endometriosis is given. An extremely important area of scientific research is precisely the interaction between the microbiota of the endometrium and its immunity, and not just the confirmation of the presence of microorganisms in the endometrium. The modern aspects of the etiology and pathogenesis of chronic endometritis and endometriosis are described. The main pathogenetic determinants of chronic endometritis are the failure of adaptation mechanisms to the constant effects of microbes and, as a consequence, the decrease and inferiority of the immune response and the development of autoimmune reactions. The modern paradigm for the development and progression of endometriosis involves the presence of bacterial contamination of the endometrium and the abdominal cavity, which in turn becomes a trigger for genetically-epigenetic modifications of cells, launching different cascades that underlie reproductive function disorders. The pathogenetically significant relationship between chronic endometritis and endometriosis is highlighted. It was revealed that chronic endometritis can be both a cause and a consequence of endometriosis. Disorders of the endometrial receptivity in chronic endometritis associated with endometriosis, their importance in the implementation of endometrial infertility are described. The important role of the microbiome in the formation of reproductive disorders is noted.

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