scholarly journals Green Oxidation Reactions of Drugs Catalyzed by Bio-inspired Complexes as an Efficient Methodology to Obtain New Active Molecules

10.5772/13524 ◽  
2011 ◽  
Author(s):  
Emerson Henrique de Faria ◽  
Gustavo Pimenta ◽  
Frederico Matias ◽  
Marcio Luis Andrade e Silva ◽  
Ademar Alves da Silva Filho ◽  
...  
Keyword(s):  
Oxidation Reactions ◽  
Green Oxidation ◽  
Green Oxidation Reactions

Green Oxidation Reactions by Polyoxometalate-Based Catalysts: From Molecular to Solid Catalysts

2010 ◽  
Vol 53 (13-14) ◽  
pp. 876-893 ◽  
Author(s):  
Noritaka Mizuno ◽  
Keigo Kamata ◽  
Kazuya Yamaguchi
Keyword(s):  
Oxidation Reactions ◽  
Solid Catalysts ◽  
Green Oxidation ◽  
Green Oxidation Reactions

“Green” oxidation reactions—application to carbohydrate chemistry

2003 ◽  
Vol 5 (6) ◽  
pp. 679-681 ◽  
Author(s):  
Ewan C. Boyd ◽  
Ray V. H. Jones ◽  
Peter Quayle ◽  
Anita J. Waring
Keyword(s):  
Oxidation Reactions ◽  
Carbohydrate Chemistry ◽  
Green Oxidation ◽  
Green Oxidation Reactions

Pillared Clay Catalysts in Green Oxidation Reactions

2010 ◽  
pp. 301-318 ◽  
Author(s):  
M.A. Vicente ◽  
R. Trujillano ◽  
K.J. Ciuffi ◽  
E.J. Nassar ◽  
S.A. Korili ◽  
...  
Keyword(s):  
Pillared Clay ◽  
Oxidation Reactions ◽  
Green Oxidation ◽  
Clay Catalysts ◽  
Green Oxidation Reactions

scholarly journals Green oxidation of indoles using halide catalysis

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Jun Xu ◽  
Lixin Liang ◽  
Haohao Zheng ◽  
Yonggui Robin Chi ◽  
Rongbiao Tong
Keyword(s):  
Chemical Synthesis ◽  
Human Health ◽  
Waste Prevention ◽  
Oxidation Reactions ◽  
Oxidation Method ◽  
Hazardous Chemical ◽  
Green Oxidation ◽  
Oxidative Rearrangement ◽  
Nitrogen Containing Compounds ◽  
By Products

Abstract Oxidation of indoles is a fundamental organic transformation to deliver a variety of synthetically and pharmaceutically valuable nitrogen-containing compounds. Prior methods require the use of either organic oxidants (meta-chloroperoxybenzoic acid, N-bromosuccinimide, t-BuOCl) or stoichiometric toxic transition metals [Pb(OAc)4, OsO4, CrO3], which produced oxidant-derived by-products that are harmful to human health, pollute the environment and entail immediate purification. A general catalysis protocol using safer oxidants (H2O2, oxone, O2) is highly desirable. Herein, we report a unified, efficient halide catalysis for three oxidation reactions of indoles using oxone as the terminal oxidant, namely oxidative rearrangement of tetrahydro-β-carbolines, indole oxidation to 2-oxindoles, and Witkop oxidation. This halide catalysis protocol represents a general, green oxidation method and is expected to be used widely due to several advantageous aspects including waste prevention, less hazardous chemical synthesis, and sustainable halide catalysis.

Mechanism of Oxidation Reactions of Bromine

1958 ◽  
Vol 14 (5_6) ◽  
pp. 357-360
Author(s):  
K. C. Grover ◽  
R. C. Mehrotra
Keyword(s):  
Oxidation Reactions ◽  
Mechanism Of Oxidation

Mechanism of Oxidation Reactions of Bromine

1958 ◽  
Vol 14 (5_6) ◽  
pp. 345-356 ◽  
Author(s):  
K. C. Grover ◽  
R. C. Mehrotra
Keyword(s):  
Oxidation Reactions ◽  
Mechanism Of Oxidation

Thermo-Oxidative Decomposition of Lovage (Levisticum officinale) and Davana (Artemisia pallens) Essential Oils under Simulated Tobacco Heating Product Conditions

2020 ◽  
Vol 29 (1) ◽  
pp. 27-43
Author(s):  
Emma Jakab ◽  
Zoltán Sebestyén ◽  
Bence Babinszki ◽  
Eszter Barta-Rajnai ◽  
Zsuzsanna Czégény ◽  
...  
Keyword(s):  
Low Temperature ◽  
Essential Oils ◽  
Relative Yield ◽  
Gas Chromatography Mass Spectrometry ◽  
Intramolecular Rearrangement ◽  
Oxidation Reactions ◽  
Pyrolysis Gas ◽  
Oxidative Decomposition ◽  
Oxidative Pyrolysis ◽  
Artemisia Pallens

SummaryThe thermo-oxidative decomposition of lovage (Levisticum officinale) and davana (Artemisia pallens) essential oils has been studied by pyrolysis-gas chromatography/mass spectrometry in 9% oxygen and 91% nitrogen atmosphere at 300 °C to simulate low-temperature tobacco heating conditions. Both lovage and davana oils contain numerous chemical substances; the main components of both oils are various oxygen-containing compounds. Isobenzofuranones are the most important constituents of lovage oil, and their relative intensity changed significantly during oxidative pyrolysis. (Z)-ligustilide underwent two kinds of decomposition reactions: an aromatization reaction resulting in the formation of butylidenephthalide and the scission of the lactone ring with the elimination of carbon dioxide or carbon monoxide. Davanone is the main component of davana oil, which did not decompose considerably during low-temperature oxidative pyrolysis. However, the relative yield of the second most intensive component, bicyclogermacrene, reduced markedly due to bond rearrangement reactions. Davana ether underwent oxidation reactions leading to the formation of various furanic compounds. The changes in the composition of both essential oils could be interpreted in terms of bond splitting, intramolecular rearrangement mechanisms and oxidation reactions of several constituents during low-temperature oxidative pyrolysis. The applied thermo-oxidative method was found to be suitable to study the stability of the essential oils and monitor the decomposition products under simulated tobacco heating conditions. In spite of the complicated composition of the essential oils, no evidence for interaction between the oil components was found. [Beitr. Tabakforsch. Int. 29 (2020) 27–43]

Oxidase Catalysis via an Aerobically Generated Dess-Martin Periodinane Analogue

2018 ◽  
Author(s):  
Asim Maity ◽  
Sung-Min Hyun ◽  
Alan Wortman ◽  
David Powers
Keyword(s):  
Chemical Synthesis ◽  
Aerobic Oxidation ◽  
Substrate Oxidation ◽  
Oxidation Catalysis ◽  
Hypervalent Iodine ◽  
Oxidation Reactions ◽  
Broad Array ◽  
Oxidation Chemistry ◽  
Reactive Oxidants

<p>Hypervalent iodine(V) reagents, such as Dess-Martin periodinane (DMP) and 2-iodoxybenzoic acid (IBX), are broadly useful oxidants in chemical synthesis. Development of strategies to access these reagents from O2 would immediately enable use of O2 as a terminal oxidant in a broad array of substrate oxidation reactions. Recently we disclosed the aerobic synthesis of I(III) reagents by intercepting reactive oxidants generated during aldehyde autoxidation. Here, we couple aerobic oxidation of iodobenzenes with disproportionation of the initially generated I(III) compounds to generate I(V) reagents. The aerobically generated I(V) reagents exhibit substrate oxidation chemistry analogous to that of DMP. Further, the developed aerobic generation of I(V) has enabled the first application of I(V) intermediates in aerobic oxidation catalysis.</p>

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