Incidence of Small Intestinal Lesions in Patients with Iron Deficiency Anemia

2011 ◽  
Vol 58 (109) ◽  
pp. 1240-1243 ◽  
Author(s):  
Atsuo Yamada ◽  
Hirotsugu Watabe ◽  
Yutaka Yamaji ◽  
Haruhiko Yoshida ◽  
Masao Omata ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Intestinal Lesions ◽  
Small Intestinal

Small Intestinal Lesions in Patients with Anemia on Hemodialysis: A Two-Center, Cross-Sectional Study

Digestion ◽  
2019 ◽  
Vol 101 (6) ◽  
pp. 730-736 ◽  
Author(s):  
Haruhiko Ozaki ◽  
Kazuhiro Ota ◽  
Yuichi Kojima ◽  
Satoshi Harada ◽  
Toshihisa Takeuchi ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Cross Sectional Study ◽  
Hemoglobin Level ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Blood Hemoglobin ◽  
Intestinal Lesions ◽  
Significant Difference ◽  
Small Intestinal

<b><i>Aim:</i></b> The number of patients on chronic dialysis in Japan is increasing every year, and the average age of these patients is also increasing annually. Iron deficiency is an important cause of anemia in patients on hemodialysis (HD). However, it has not been clarified whether these patients might have small intestinal mucosal lesions causing iron deficiency anemia. <b><i>Methods:</i></b> We conducted a cross-sectional study in ­asymptomatic patients on HD between April 2014 and ­December 2015. We performed small bowel capsule endoscopy (SBCE) and analyzed the relationship between small intestinal endoscopic findings and anemia. <b><i>Results:</i></b> SBCE was successfully completed in 39 eligible patients. Univariate analysis revealed that there was a significant difference in blood hemoglobin levels between the morbid SBCE-finding group (median 7.7 g/dL; range 6.7–9.2 g/dL) and the non-morbid SBCE-finding group (median 10.65 g/dL; range 6.4–13.1 g/dL; <i>p</i> = 0.0006, Mann-Whitney U test). On multivariate analysis, the blood hemoglobin level was an independent predictor of morbid SBCE findings (<i>p</i> = 0.0033). The cutoff value of blood hemoglobin level for the morbid SBCE finding was determined as 9.2 g/dL using receiver operating characteristic curve analysis. <b><i>Conclusions:</i></b> Patients on HD with anemia are at a high risk of small intestinal lesions. Since the control of small intestinal lesion may improve the anemia, these outcomes are significant factors for managing patients on HD.

Effects of iron therapy on pituitary gonadal axis and sperm parameters in adults with iron deficiency anemia (IDA)

2013 ◽  
Author(s):  
Ashraf Soliman ◽  
Mohamed Yassin ◽  
Osman Abdelrahmanm ◽  
Vincenzo Desanctis ◽  
Ahmed Elawwa
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Sperm Parameters ◽  
Iron Therapy ◽  
Deficiency Anemia
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