Small Intestinal Lesions in Patients with Anemia on Hemodialysis: A Two-Center, Cross-Sectional Study

Digestion ◽  
2019 ◽  
Vol 101 (6) ◽  
pp. 730-736 ◽  
Author(s):  
Haruhiko Ozaki ◽  
Kazuhiro Ota ◽  
Yuichi Kojima ◽  
Satoshi Harada ◽  
Toshihisa Takeuchi ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Cross Sectional Study ◽  
Hemoglobin Level ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Blood Hemoglobin ◽  
Intestinal Lesions ◽  
Significant Difference ◽  
Small Intestinal

<b><i>Aim:</i></b> The number of patients on chronic dialysis in Japan is increasing every year, and the average age of these patients is also increasing annually. Iron deficiency is an important cause of anemia in patients on hemodialysis (HD). However, it has not been clarified whether these patients might have small intestinal mucosal lesions causing iron deficiency anemia. <b><i>Methods:</i></b> We conducted a cross-sectional study in ­asymptomatic patients on HD between April 2014 and ­December 2015. We performed small bowel capsule endoscopy (SBCE) and analyzed the relationship between small intestinal endoscopic findings and anemia. <b><i>Results:</i></b> SBCE was successfully completed in 39 eligible patients. Univariate analysis revealed that there was a significant difference in blood hemoglobin levels between the morbid SBCE-finding group (median 7.7 g/dL; range 6.7–9.2 g/dL) and the non-morbid SBCE-finding group (median 10.65 g/dL; range 6.4–13.1 g/dL; <i>p</i> = 0.0006, Mann-Whitney U test). On multivariate analysis, the blood hemoglobin level was an independent predictor of morbid SBCE findings (<i>p</i> = 0.0033). The cutoff value of blood hemoglobin level for the morbid SBCE finding was determined as 9.2 g/dL using receiver operating characteristic curve analysis. <b><i>Conclusions:</i></b> Patients on HD with anemia are at a high risk of small intestinal lesions. Since the control of small intestinal lesion may improve the anemia, these outcomes are significant factors for managing patients on HD.

scholarly journals Iron deficiency anemia among hospitalized children in a rural teaching hospital: a cross sectional study

2018 ◽  
Vol 5 (4) ◽  
pp. 1631
Author(s):  
Inderpreet Santokh ◽  
Bablu Kumar Gaur ◽  
Raghvendra Narayan ◽  
Baljeet Maini ◽  
A. K. Bharadwaj
Keyword(s):  
Socioeconomic Status ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Cross Sectional Study ◽  
Hemoglobin Level ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Low Socioeconomic

Background: Iron deficiency anemia is the most common nutritional deficiency disorder in the world. The present study was conducted to know the prevalence and severity of iron deficiency anemia among of 6 months to 60 months old children. A large proportion of iron deficiency is preventable with appropriate and timely intervention.Methods: This cross-sectional study was done on 100 children clinically suggestive of anemia with hemoglobin level less than 11gm/dl admitted in pediatrics ward of tertiary care hospital. 5 ml of blood sample was taken and complete hemogram, peripheral blood film and serum ferritin estimation was done. Case were studied in reference to history, age, clinical examination, hemoglobin level and confirmation of iron deficiency anemia was done by serum ferritin levels.Results: The prevalence of iron deficiency anemia in present study was 56%. It was most prevalent in the age group of 6 to 24 months. Exclusively breastfed children showed higher prevalence of iron deficiency anemia in present study, however no statistical correlation was found. Low Serum ferritin levels have statistically significant result with socioeconomic status, with as many as 69.4% suffering from iron deficiency anemia belonging to low socioeconomic status.Conclusions: Prevalence of iron deficiency anemia remains alarmingly high and major health problem in our country. All anemia are not iron deficiency anemia. Low socioeconomic status is a huge hurdle in child health and greatly influences prevalence of iron deficiency anemia. Serum ferritin is a most sensitive marker of iron deficiency anemia, helps diagnose it early in its course, which can be missed on clinical or routine blood investigations.

scholarly journals Association between Helicobacter Pylori Infection and Iron Deficiency Anemia: A Cross Sectional Study

2020 ◽  
Vol 38 (2) ◽  
pp. 68-78
Author(s):  
Anisur Rahman ◽  
ASMA Raihan ◽  
Dewan Saifuddin Ahmed ◽  
Mohammad Enamul Karim ◽  
Atia Saeed ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Deficiency Anaemia ◽  
Cross Sectional Study ◽  
Hemoglobin Level ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Erosive Gastritis ◽  
Cross Sectional ◽  
H Pylori

Background: Helicobacter pylori (H. pylori) remains one of the most common worldwide human infections and is associated with a number of important upper gastrointestinal (GI) conditions including chronic gastritis, peptic ulcer disease, gastric carcinoma and special type of lymphoma. Anaemia is a common disorder in developing countries and the commonest cause is iron deficiency. There are many causes for high prevalence of this disorder in our society, many are well-known and investigated while some are new and not well established. Although H. pylori associates peptic ulcers and gastric malignancy can cause bleeding, resulting in iron deficiency, but majority of patients infected with H. pylori does not have ulcer or malignancy. They usually have chronic gastritis that is not associated with GI bleeding. About 35% of iron deficiency anaemia cases remain unexplained after a gastrointestinal evaluation. Recently investigation focused on the role of H. pylori, in the development of extra-gastrointestinal diseases including Iron deficiency anaemia. Methodology: This observational, cross sectional study was carried out at BSMMU, Dhaka from July 2010 to October 2011 to find out the association between H. pylori infection and iron deficiency anemia in Bangladeshi adults. Patients with dyspepsia and indication of upper GI endoscopy were initially enrolled in the study and finally a total of 168 subjects were included based on inclusion and exclusion criteria. Result: Among 168 patients, 105 (62.5%) were male and 63(37.5%) were female with the mean age of 33.25 years. On endoscopy, 147(87.5%) of the patients had normal findings and 21(12.5 %) had erosive gastritis. None of them had hemorrhagic erosive gastritis. Among 168 patients, 115(68.45%) were positive and 53(31.55%) were negative for H. pylori by rapid urease test. In our study, we have found a significant low mean serum ferritin level (P<0.001) in H. pylori infected patients. This result is consistent with most of previous data concerning the effect of H. pylori infection on iron metabolism. This study has also revealed a significant (P<0.001) lower value of mean MCV and MCH in H. pylori positive patients. Regarding hemoglobin value, our study has showed no significant (P>0.05) different in hemoglobin level according to H. pylori status. Conclusion: Though there was no significant low hemoglobin level in our study, mean hemoglobin level was low in H. pylori positive patient. In our study H. pylori was not significantly associated with iron deficiency anemia but it was significantly associated with iron deficiency. J Bangladesh Coll Phys Surg 2020; 38(2): 68-78

scholarly journals Contributing factors to iron deficiency anemia in women in Jordan: A single-center cross-sectional study

PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0205868 ◽  
Author(s):  
Muhammad Awidi ◽  
Hisham Bawaneh ◽  
Hadil Zureigat ◽  
Muna AlHusban ◽  
Abdalla Awidi
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Cross Sectional Study ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Single Center ◽  
Contributing Factors ◽  
Cross Sectional

Iron deficiency anemia in an Egyptian pediatric population: A cross-sectional study

2015 ◽  
Vol 14 (1) ◽  
pp. 25 ◽  
Author(s):  
EmanFawzy Halawa ◽  
SamarMohamed Sabry ◽  
Dalia Ahmed ◽  
MohamedM. E. Al Ghwass
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Pediatric Population ◽  
Cross Sectional Study ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Impact of iron deficiency anemia on chronic periodontitis and superoxide dismutase activity: a cross-sectional study

2014 ◽  
Vol 44 (2) ◽  
pp. 57 ◽  
Author(s):  
Souvik Chakraborty ◽  
Shikha Tewari ◽  
Rajinder Kumar Sharma ◽  
Satish Chander Narula ◽  
Pratap Singh Ghalaut ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Chronic Periodontitis ◽  
Cross Sectional Study ◽  
Superoxide Dismutase Activity ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Cross Sectional
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