scholarly journals Detection of Superoxide Anion Radical in a Stratum Corneum Intercellular Lipid Model Using an Electrochemical Sensor

2011 ◽  
Vol 60 (12) ◽  
pp. 647-654 ◽  
Author(s):  
Teruhisa Kaneko ◽  
Chihiro Kaise ◽  
Yoko Kimoto ◽  
Shota Suzuki ◽  
Takeshi Kondo ◽  
...  
NANO ◽  
2017 ◽  
Vol 12 (01) ◽  
pp. 1750006 ◽  
Author(s):  
Jujie Ren ◽  
Miao Zhai ◽  
Min Cui ◽  
Liujia Li ◽  
Congcong Yu ◽  
...  

A superoxide anion radical (O[Formula: see text] nonenzymatic electrochemical sensor based on PtRuCu ternary alloy nanoparticles/electrochemically reduced graphene oxide (ERGO) composite modified glassy carbon electrode (PtRuCu/ERGO/GCE) was developed. ERGO and PtRuCu/ERGO composites were characterized by scanning electron microscopy. The prepared PtRuCu/ERGO/GCE showed remarkable performance toward the electrocatalytic reduction of (O[Formula: see text]. The sensor possessed a high sensitivity of 1725[Formula: see text]A[Formula: see text][Formula: see text][Formula: see text]mM[Formula: see text][Formula: see text]cm[Formula: see text], a wide linear range of 7.5–330[Formula: see text][Formula: see text]M ([Formula: see text]0.993) and a low detection limit of 0.7[Formula: see text][Formula: see text]M ([Formula: see text]/[Formula: see text]), as well as excellent selectivity, reproducibility and stability, which can be attributed to the synergistic effect of ERGO and PtRuCu ternary alloy nanoparticles. Therefore, the prepared sensor is promising for electrochemical determination of O[Formula: see text].


2019 ◽  
Vol 855 ◽  
pp. 113653 ◽  
Author(s):  
Huanhuan Zhang ◽  
Xuan Cai ◽  
Hongli Zhao ◽  
Wenqian Sun ◽  
Zhenxing Wang ◽  
...  

2009 ◽  
Vol 47 (7) ◽  
pp. 1039-1048 ◽  
Author(s):  
Motoki Fujita ◽  
Ryosuke Tsuruta ◽  
Shunji Kasaoka ◽  
Kenji Fujimoto ◽  
Ryo Tanaka ◽  
...  

2015 ◽  
Vol 22 (37) ◽  
pp. 4234-4256 ◽  
Author(s):  
Renan Chiste ◽  
Marisa Freitas ◽  
Adriana Mercadante ◽  
Eduarda Fernandes

2014 ◽  
Vol 12 (3) ◽  
pp. 377-385 ◽  
Author(s):  
Vesna Šaponjac ◽  
Dragana Četojević-Simin ◽  
Gordana Ćetković ◽  
Jasna Čanadanović-Brunet ◽  
Sonja Djilas ◽  
...  

AbstractGround spice paprika was extracted with hexane, by conventional Soxhlet procedure (SX oleoresin), and with supercritical carbon dioxide at three different pressures — 20, 30 and 40 MPa (SF20, SF30 and SF40 oleoresins). The effect of extraction method and conditions on the colour intesity of paprika oleoresins, content of α-tocopherol, as well as antioxidant and antiproliferative activity was examined. Hexane showed highest selectivity for paprika pigments (886.02 ASTA), while α-tocopherol showed highest solubility (3846.9 mg kg−1) in supercritical carbon dioxide at 20 MPa. All paprika oleoresins exhibited good superoxide anion radical scavenging activity SF30 being the best superoxide anion radical scavenger. Cell growth activity was evaluated in vitro in human cell lines:cervix epitheloid carcinoma (HeLa), breast adenocarcinoma (MCF7) and colon adenocarcinoma (HT-29). The highest antiproliferative activity was exhibited by SX in MCF7 cell line (IC50=14.28 mg mL−1). Extract SF40 produced significant and selective antiproliferative action towards HeLa cell line. These results suggest that paprika oleoresins, due to high antiradical and tumor cell-inhibiting activity, can be regarded as functional food ingredients.


Sign in / Sign up

Export Citation Format

Share Document