Physico-Chemical Stability of Flaxseed Oil with Natural Antioxidant Mixtures during Heating

Irwandi JASWIR; David D. KITTS; Yaakob B. Che MAN; Torla H. HASSAN

doi:10.5650/jos.54.71

Microencapsulation of Flaxseed Oil—State of Art

Processes ◽

10.3390/pr9020295 ◽

2021 ◽

Vol 9 (2) ◽

pp. 295

Author(s):

Asma Yakdhane ◽

Sabrine Labidi ◽

Donia Chaabane ◽

Anita Tolnay ◽

Arijit Nath ◽

...

Keyword(s):

Fatty Acids ◽

Gum Arabic ◽

Tween 80 ◽

Flaxseed Oil ◽

Review Article ◽

Wall Material ◽

Physico Chemical ◽

Comprehensive Information ◽

The Matrix

Microencapsulation is a well-known technology for the lipid delivery system. It prevents the oxidation of fatty acids and maintains the quality of lipid after extraction from oil seed and processing. In flaxseed oil, the amount of ω-3 and ω-6 polyunsaturated fatty acids are 39.90–60.42% and 12.25–17.44%, respectively. A comprehensive review article on the microencapsulation of flaxseed oil has not been published yet. Realizing the great advantages of flaxseed oil, information about different technologies related to the microencapsulation of flaxseed oil and their characteristics are discussed in a comprehensive way, in this review article. To prepare the microcapsule of flaxseed oil, an emulsion of oil-water is performed along with a wall material (matrix), followed by drying with a spray-dryer or freeze-dryer. Different matrices, such as plant and animal-based proteins, maltodextrin, gum Arabic, and modified starch are used for the encapsulation of flaxseed oil. In some cases, emulsifiers, such as Tween 80 and soya lecithin are used to prepare flaxseed oil microcapsules. Physico-chemical and bio-chemical characteristics of flaxseed oil microcapsules depend on process parameters, ratio of oil and matrix, and characteristics of the matrix. As an example, the size of the microcapsule, prepared with spray-drying and freeze-drying ranges between 10–400 and 20–5000 μm, respectively. It may be considered that the comprehensive information on the encapsulation of flaxseed oil will boost the development of functional foods and biopharmaceuticals.

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Physico‐chemical stability of Plasma‐Lyte 148® and Plasma‐Lyte 148® + 5% Glucose with eight common intravenous medications

Pediatric Anesthesia ◽

10.1111/pan.13554 ◽

2019 ◽

Vol 29 (2) ◽

pp. 186-192

Author(s):

Rachael Dawson ◽

Andrew Wignell ◽

Paul Cooling ◽

David Barrett ◽

Harish Vyas ◽

...

Keyword(s):

Chemical Stability ◽

Physico Chemical

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Physico-chemical stability of casein micelles cross-linked by transglutaminase as a function of acidic pH

Food Structure ◽

10.1016/j.foostr.2018.100103 ◽

2019 ◽

Vol 19 ◽

pp. 100103 ◽

Cited By ~ 6

Author(s):

Márcio H. Nogueira ◽

Guilherme M. Tavares ◽

Naaman F. Nogueira Silva ◽

Federico Casanova ◽

Paulo C. Stringheta ◽

...

Keyword(s):

Chemical Stability ◽

Acidic Ph ◽

Casein Micelles ◽

Physico Chemical

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Evaluations about the physico-chemical stability of docetaxel and irinotecan pre-diluted and diluted solutions: pharmaco-economic perspectives

Drugs and Therapy Studies ◽

10.4081/dts.2013.e6 ◽

2013 ◽

Vol 3 (1) ◽

pp. 6 ◽

Cited By ~ 1

Author(s):

Mariarita Laforgia ◽

Anna Elisa Quatrale ◽

Nicola A. Colabufo ◽

Amalia Azzariti ◽

Angelo Paradiso ◽

...

Keyword(s):

Chemical Stability ◽

Mobile Phase ◽

Ammonium Acetate ◽

Physical Stability ◽

Experimental Conditions ◽

Phase Gradient ◽

Methanol Mixture ◽

Physico Chemical ◽

Starting Point ◽

Economic Perspectives

Several clinically used anticancer drugs are well-known as far as their pharmacologic properties are concerned, but scarcely ever the interest towards their physico-chemical characteristics in solution led to practical acknowledgement in their management. Thanks to the Units for Centralized Anticancer Drug Handling, the importance to evaluate the concentration of saturation (physical stability) or the possible transformations undergone by a drug in solution (chemical stability) has become the starting point for avoiding useless wasting drugs and economic resources. By HPLC experiments we have demonstrated that the solutions of two drugs, docetaxel and irinotecan, are particularly stable at different concentrations and times of analyses in our experimental conditions. The best mobile phase for docetaxel was water/methanol/acetonitrile in 42/32/26 volumetric ratio: for halving concentrations (0.72-0.36-0.18-0.09 mg/mL) in NaCl 0.9%, the highest value gave a six-day and the three lower concentrations a fourteen-day stability, when storage occurred at room temperature and light protected. Elution of irinotecan was possible through an analysis in mobile phase gradient: at t0 a 20% ammonium acetate 10 mM and 80% methanol mixture, and after 5 min, a 80% ammonium acetate 10 mM and 20% methanol mixture. The physico-chemical stability was showed for five days, for any concentration of analysis when storage occurred at 2-8°C and light protected.

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