scholarly journals Synthesis of Polymeric Reconstituted Hemoglobins as Superoxide Dismutase Mimics Designed for Long-term Circulation Maintenance

2005 ◽  
Vol 54 (7) ◽  
pp. 413-418 ◽  
Author(s):  
Makoto YUASA ◽  
Kenichi OYAIZU ◽  
Takamitsu HAYASHI ◽  
Aritomo YAMAGUCHI
Keyword(s):  
Superoxide Dismutase ◽  
Superoxide Dismutase Mimics

scholarly journals Manganese-Based Superoxide Dismutase Mimics Modify Both Acute and Long-Term Outcome Severity in aDrosophila melanogasterModel of Classic Galactosemia

2014 ◽  
Vol 20 (15) ◽  
pp. 2361-2371 ◽  
Author(s):  
Patricia P. Jumbo-Lucioni ◽  
Emily L. Ryan ◽  
Marquise L. Hopson ◽  
Heather M. Bishop ◽  
Tin Weitner ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Classic Galactosemia ◽  
Outcome Severity ◽  
Superoxide Dismutase Mimics

Immunolocalization of antioxidant enzymes in testis of rams submitted to long-term heat stress

Zygote ◽  
2019 ◽  
Vol 27 (6) ◽  
pp. 432-435
Author(s):  
Thais Rose dos Santos Hamilton ◽  
Gabriela Esteves Duarte ◽  
José Antonio Visintin ◽  
Mayra Elena Ortiz D’Ávila Assumpção
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Antioxidant Enzymes ◽  
Heat Stress ◽  
Glutathione Peroxidase ◽  
Cell Types ◽  
Treated Group ◽  
Oxidative Balance ◽  
Testicular Cells

SummaryLong-term heat stress (HS) induced by testicular insulation generates oxidative stress (OS) on the testicular environment; consequently activating antioxidant enzymes such as superoxide dismutase (SOD), glutathione reductase (GR) and glutathione peroxidase (GPx). The aim of this work was to immunolocalize antioxidant enzymes present in different cells within the seminiferous tubule when rams were submitted to HS. Rams were divided into control (n = 6) and treated group (n = 6), comprising rams subjected to testicular insulation for 240 h. After the testicular insulation period, rams were subjected to orchiectomy. Testicular fragments were submitted to immunohistochemistry for staining against SOD, GR and GPx enzymes. We observed immunolocalization of GPx in more cell types of the testis after HS and when compared with other enzymes. In conclusion, GPx is the main antioxidant enzyme identified in testicular cells in an attempt to maintain oxidative balance when HS occurs.

Modification of inflammatory response to implanted biomedical materialsin vivo by surface bound superoxide dismutase mimics

2000 ◽  
Vol 51 (4) ◽  
pp. 549-560 ◽  
Author(s):  
Kishore Udipi ◽  
Richard L. Ornberg ◽  
K. Bruce Thurmond ◽  
Steven L. Settle ◽  
Denis Forster ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Inflammatory Response ◽  
Superoxide Dismutase Mimics

scholarly journals The activity of the first line enzymes of the antioxidant defence in the liver of pubertal rats during stress

2012 ◽  
Vol 58 (5) ◽  
pp. 573-578 ◽  
Author(s):  
Y.V. Volkova ◽  
L.L. Sukhova ◽  
V.V. Davydov ◽  
A.V. Goloborodko
Keyword(s):  
Superoxide Dismutase ◽  
Glutathione Peroxidase ◽  
Immobilization Stress ◽  
First Line ◽  
Short Term ◽  
Antioxidant Defence ◽  
Defence Enzymes ◽  
Antioxidant Defence Enzymes

The purpose of the work was to study the activity of the first line antioxidant defence enzymes in postmitochondrial fraction of liver of pubertal rats during immobilization stress. During short-term immobilization the activity of catalase and glutathione peroxidase (GPx) decreased. Long-term immobilization was accompanied by activation of GPx and superoxide dismutase in the liver postmitochondrial fraction of late pubertal and adult animals, but not early pubertal rats.

Short-term and long-term variability of indices related to nutritional status. I: Ca, Cu, Fe, Mg, and Zn.

1989 ◽  
Vol 35 (3) ◽  
pp. 369-373 ◽  
Author(s):  
S K Gallagher ◽  
L K Johnson ◽  
D B Milne
Keyword(s):  
Superoxide Dismutase ◽  
Nutritional Status ◽  
Iron Status ◽  
Short Term ◽  
Free Living ◽  
Analytical Technique ◽  
Metabolic Unit ◽  
Biological Component ◽  
Analytical Variation

Abstract Five free-living women (ages 28-38 y) and five women (ages 23-44 y) residing in a metabolic unit and eating a constant diet were assessed for variation in indices related to mineral nutrition. Blood was sampled once a month for five months, once a week for five weeks, and once a day for five days to assess analytical and biological variability. Analytical variability was determined by using concurrently run duplicate control samples prepared from plasma or serum pools. Of the measured indices, serum ferritin varied most, with intra-individual variance of 4.72% to 18.0%. Much of this variance may have been because of changes in iron status or in the analytical technique used. Intra-individual month-to-month variance for other indices ranged from 17% for superoxide dismutase (EC 1.15.1.1) to 1.5% for calcium. Correction for long-term analytical variation indicated that most of the variance was associated with the biological component. The higher biological variabilities of some indices, including ferritin or superoxide dismutase, need to be considered when nutritional status is being evaluated or when serial observations are made over a protracted period in clinical studies or trials.

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