scholarly journals Effects of Conjugated Linoleic Acid (CLA) on Abdominal Fat Accumulation. Comparison with Other Dietary Oils.

2001 ◽  
Vol 50 (2) ◽  
pp. 129-132 ◽  
Author(s):  
Mahoko HAMURA ◽  
Satoshi KUDO
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Abdominal Fat ◽  
Fat Accumulation ◽  
Dietary Oils

Effects of conjugated linoleic acid (CLA) on fat accumulation, activity, and proteomics analysis in Caenorhabditis elegans

2018 ◽  
Vol 249 ◽  
pp. 193-201 ◽  
Author(s):  
Peiyi Shen ◽  
Jonathan C. Kershaw ◽  
Yiren Yue ◽  
Ou Wang ◽  
Kee-Hong Kim ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Caenorhabditis Elegans ◽  
Conjugated Linoleic Acid ◽  
Proteomics Analysis ◽  
Fat Accumulation

Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake

1999 ◽  
Vol 276 (4) ◽  
pp. R1172-R1179 ◽  
Author(s):  
James P. DeLany ◽  
Fawn Blohm ◽  
Alycia A. Truett ◽  
Joseph A. Scimeca ◽  
David B. West
Keyword(s):  
Body Composition ◽  
Linoleic Acid ◽  
Food Intake ◽  
Conjugated Linoleic Acid ◽  
Energy Intake ◽  
Body Fat ◽  
Metabolic Effects ◽  
Protein Accumulation ◽  
High Fat ◽  
Fat Accumulation

Recent reports have demonstrated that conjugated linoleic acid (CLA) has effects on body fat accumulation. In our previous work, CLA reduced body fat accumulation in mice fed either a high-fat or low-fat diet. Although CLA feeding reduced energy intake, the results suggested that some of the metabolic effects were not a consequence of the reduced food intake. We therefore undertook a study to determine a dose of CLA that would have effects on body composition without affecting energy intake. Five doses of CLA (0.0, 0.25, 0.50, 0.75, and 1.0% by weight) were studied in AKR/J male mice ( n = 12/group; age, 39 days) maintained on a high-fat diet (%fat 45 kcal). Energy intake was not suppressed by any CLA dose. Body fat was significantly lower in the 0.50, 0.75, and 1.0% CLA groups compared with controls. The retroperitoneal depot was most sensitive to the effects of CLA, whereas the epididymal depot was relatively resistant. Higher doses of CLA also significantly increased carcass protein content. A time-course study of the effects of 1% CLA on body composition showed reductions in fat pad weights within 2 wk and continued throughout 12 wk of CLA feeding. In conclusion, CLA feeding produces a rapid, marked decrease in fat accumulation, and an increase in protein accumulation, at relatively low doses without any major effects on food intake.

scholarly journals Thetrans-10,cis-12 isomer of conjugated linoleic acid reduces hepatic triacylglycerol content without affecting lipogenic enzymes in hamsters

2004 ◽  
Vol 92 (3) ◽  
pp. 383-389 ◽  
Author(s):  
Amaia Zabala ◽  
Itziar Churruca ◽  
M. Teresa Macarulla ◽  
Víctor M. Rodríguez ◽  
Alfredo Fernández-Quintela ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Regulatory Element ◽  
Liver Weight ◽  
Liver Fat ◽  
Mrna Levels ◽  
Lipogenic Enzymes ◽  
Fat Accumulation ◽  
Triacylglycerol Content ◽  
Hepatic Triacylglycerol

Conjugated linoleic acid (CLA) refers to the positional and geometric dienoic isomers of linoleic acid. The dietary intake of CLA has been associated with changes in lipid metabolism. The aim of the present work was to assess the effects of the two main isomers of CLA on sterol regulatory element binding protein (SREBP)-1a and SREBP-1c mRNA levels, as well as on mRNA levels and the activities of several lipogenic enzymes in liver. For this purpose hamsters were fed an atherogenic diet supplemented with 5 g linoleic acid,cis-9,trans-11 ortrans-10,cis-12 CLA/kg diet for 6 weeks. Thetrans-10,cis-12 isomer intake produced significantly greater liver weight, but also significantly decreased liver fat accumulation. No changes in mRNA levels of SREBP-1a, SREBP-1c and lipogenic enzymes, or in the activities of these enzymes, were observed. There was no effect of feedingcis-9,trans-11 CLA. These results suggest that increased fat accumulation in liver does not occur on the basis of liver enlargement produced by feeding thetrans-10,cis-12 isomer of CLA in hamsters. The reduction in hepatic triacylglycerol content induced by this isomer was not attributable to changes in lipogenesis.

Effects of fatty acid sources on conjugated linoleic acid (CLA) and other fatty acids in dairy milk

2007 ◽  
Vol 2007 ◽  
pp. 20-20
Author(s):  
Nonthasak Piamphon ◽  
Chalong Wachirapakorn ◽  
Metha Wanapat ◽  
Chainarong Nawanukrow
Keyword(s):  
Oleic Acid ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Groundnut Oil ◽  
Rumen Microbes ◽  
Dietary Oils ◽  
Dairy Milk ◽  
Plant Sources

Conjugated linoleic acid (CLA) is aniticarcinogenic, antiatherogenic and antidiabetogenic actives. Research has therefore focused on methods of increasing CLA content in milk fat. Amount of CLA in milk fat was highly related to biohydrogenation of unsaturated fatty acid of rumen microbes. (Bauman et al., 1999). Linoleic acid (C18:2) were the precursors of CLA synthesis. The CLA was also synthesized in the mammary gland of lactating ruminants, using oleic acid (C18:1) as a precursor and activity of delta 9-desaturase (Griinari and Bauman, 1999). Linoleic acid is high in soybean oil (SO) (54.4%) and tuna oil (TO) (20.3%) while oleic acid is high in pork oil (PO) (43.5%) and groundnut oil (GO) (40.7%). Therefore, the objective of this experiment was to compare the increasing of CLA and fatty acid composition in milk fat form cows fed dietary oils obtained from either animal or plant sources.

scholarly journals Weak effect of trans-10, cis-12-conjugated linoleic acid on body fat accumulation in adult hamsters

2009 ◽  
Vol 102 (11) ◽  
pp. 1583 ◽  
Author(s):  
Jonatan Miranda ◽  
Itziar Churruca ◽  
Alfredo Fernández-Quintela ◽  
Victor Manuel Rodríguez ◽  
María Teresa Macarulla ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Weak Effect ◽  
Fat Accumulation

Isomer-Specific Effect of Conjugated Linoleic Acid on Inflammatory Adipokines Associated with Fat Accumulation in 3T3-L1 Adipocytes

2006 ◽  
Vol 9 (3) ◽  
pp. 307-312 ◽  
Author(s):  
In-Sook Ahn ◽  
Bong-Hyuk Choi ◽  
Jung-Heun Ha ◽  
Jae-Min Byun ◽  
Hyun-Gil Shin ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Specific Effect ◽  
Fat Accumulation
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