Increased Energy Metabolism and Suppressed Body Fat Accumulation in Mice by a Low Concentration of Conjugated Linoleic Acid

2001 ◽  
Vol 65 (10) ◽  
pp. 2200-2204 ◽  
Author(s):  
Koichiro OHNUKI ◽  
Satoshi HARAMIZU ◽  
Kengo ISHIHARA ◽  
Tohru FUSHIKI
Keyword(s):  
Linoleic Acid ◽  
Energy Metabolism ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Fat Accumulation ◽  
Low Concentration

Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake

1999 ◽  
Vol 276 (4) ◽  
pp. R1172-R1179 ◽  
Author(s):  
James P. DeLany ◽  
Fawn Blohm ◽  
Alycia A. Truett ◽  
Joseph A. Scimeca ◽  
David B. West
Keyword(s):  
Body Composition ◽  
Linoleic Acid ◽  
Food Intake ◽  
Conjugated Linoleic Acid ◽  
Energy Intake ◽  
Body Fat ◽  
Metabolic Effects ◽  
Protein Accumulation ◽  
High Fat ◽  
Fat Accumulation

Recent reports have demonstrated that conjugated linoleic acid (CLA) has effects on body fat accumulation. In our previous work, CLA reduced body fat accumulation in mice fed either a high-fat or low-fat diet. Although CLA feeding reduced energy intake, the results suggested that some of the metabolic effects were not a consequence of the reduced food intake. We therefore undertook a study to determine a dose of CLA that would have effects on body composition without affecting energy intake. Five doses of CLA (0.0, 0.25, 0.50, 0.75, and 1.0% by weight) were studied in AKR/J male mice ( n = 12/group; age, 39 days) maintained on a high-fat diet (%fat 45 kcal). Energy intake was not suppressed by any CLA dose. Body fat was significantly lower in the 0.50, 0.75, and 1.0% CLA groups compared with controls. The retroperitoneal depot was most sensitive to the effects of CLA, whereas the epididymal depot was relatively resistant. Higher doses of CLA also significantly increased carcass protein content. A time-course study of the effects of 1% CLA on body composition showed reductions in fat pad weights within 2 wk and continued throughout 12 wk of CLA feeding. In conclusion, CLA feeding produces a rapid, marked decrease in fat accumulation, and an increase in protein accumulation, at relatively low doses without any major effects on food intake.

scholarly journals Weak effect of trans-10, cis-12-conjugated linoleic acid on body fat accumulation in adult hamsters

2009 ◽  
Vol 102 (11) ◽  
pp. 1583 ◽  
Author(s):  
Jonatan Miranda ◽  
Itziar Churruca ◽  
Alfredo Fernández-Quintela ◽  
Victor Manuel Rodríguez ◽  
María Teresa Macarulla ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Weak Effect ◽  
Fat Accumulation

Effects of conjugated linoleic acid on body fat accumulation and serum lipids in hamsters fed an atherogenic diet

2003 ◽  
Vol 59 (3) ◽  
pp. 193-199 ◽  
Author(s):  
V. Navarro ◽  
A. Zabala ◽  
M. T. Macarulla ◽  
A. Fernández-Quintela ◽  
V. M. Rodríguez ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Serum Lipids ◽  
Atherogenic Diet ◽  
Fat Accumulation

Effects of conjugated linoleic acid on serum leptin concentration, body-fat accumulation, and β-oxidation of fatty acid in OLETF rats

Nutrition ◽  
2001 ◽  
Vol 17 (5) ◽  
pp. 385-390 ◽  
Author(s):  
Shaikh Mizanoor Rahman ◽  
Yu-Ming Wang ◽  
Hiroaki Yotsumoto ◽  
Jae-Young Cha ◽  
Seo-Young Han ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Serum Leptin ◽  
Fat Accumulation ◽  
Oletf Rats

Conjugated Linoleic Acid Combined with Physical Activity Reduces Body Fat Accumulation But Does Not Modify Lean Body Mass in Male and Female Wistar Rats

2012 ◽  
Vol 15 (4) ◽  
pp. 406-412 ◽  
Author(s):  
Jocelem Mastrodi Salgado ◽  
Tânia Rachel Baroni Ferreira ◽  
Carlos M. Donado-Pestana ◽  
Omer Cavalcanti de Almeida ◽  
Aline Mouro Ribeiro das Neves ◽  
...  
Keyword(s):  
Physical Activity ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Wistar Rats ◽  
Male And Female ◽  
Fat Accumulation ◽  
Female Wistar Rats

Conjugated Linoleic Acid (CLA) Prevents Body Fat Accumulation and Weight Gain in an Animal Model

2007 ◽  
Vol 72 (8) ◽  
pp. S612-S617 ◽  
Author(s):  
Y. Park ◽  
K.J. Albright ◽  
J.M. Storkson ◽  
W. Liu ◽  
M.W. Pariza
Keyword(s):  
Animal Model ◽  
Weight Gain ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Fat Accumulation

scholarly journals A Supplement Containing Trans-10, Cis-12 Conjugated Linoleic Acid Reduces Milk Fat Yield but Does Not Alter Organ Weight or Body Fat Deposition in Lactating Ewes

2010 ◽  
Vol 140 (11) ◽  
pp. 1949-1955 ◽  
Author(s):  
Liam A. Sinclair ◽  
Weerasinghe M. P. B. Weerasinghe ◽  
Robert G. Wilkinson ◽  
Michael J. de Veth ◽  
Dale E. Bauman
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Milk Fat ◽  
Fat Deposition ◽  
Organ Weight ◽  
Fat Yield

Effects of conjugated linoleic acid (CLA) on fat accumulation, activity, and proteomics analysis in Caenorhabditis elegans

2018 ◽  
Vol 249 ◽  
pp. 193-201 ◽  
Author(s):  
Peiyi Shen ◽  
Jonathan C. Kershaw ◽  
Yiren Yue ◽  
Ou Wang ◽  
Kee-Hong Kim ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Caenorhabditis Elegans ◽  
Conjugated Linoleic Acid ◽  
Proteomics Analysis ◽  
Fat Accumulation
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