scholarly journals The value of left atrial strain and strain rate in predicting left atrial appendage stasis in patients with nonvalvular atrial fibrillation

2018 ◽  
Vol 25 (1) ◽  
pp. 87-96 ◽  
Author(s):  
Meng-Ruo Zhu ◽  
Man Wang ◽  
Xin-Xin Ma ◽  
Dong-Yan Zheng ◽  
Yue-Li Zhang
Cardiology ◽  
2012 ◽  
Vol 121 (4) ◽  
pp. 255-260 ◽  
Author(s):  
Sakir Arslan ◽  
Ziya Simsek ◽  
Fuat Gundogdu ◽  
Enbiya Aksakal ◽  
Mehmet Emin Kalkan ◽  
...  

2010 ◽  
Vol 55 (10) ◽  
pp. A93.E879
Author(s):  
Jhih-Yuan Shih ◽  
Wei-Chuan Tsai ◽  
Yao-Yi Huang ◽  
Yen-Wen Liu ◽  
Chih-Chan Lin ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Yu Wang ◽  
Mingqi Li ◽  
Lishan Zhong ◽  
Siqi Ren ◽  
Hezhi Li ◽  
...  

Left atrial appendage (LAA) dysfunction identified by transesophageal echocardiography (TEE) is a powerful predictor of stroke in patients with atrial fibrillation (AF). The aim of our study is to assess if there is a correlation between the left atrial (LA) functional parameter and LAA dysfunction in the AF patients. This cross-sectional study included a total of 249 Chinese AF patients who did not have cardiac valvular diseases and were undergoing cardiac ablation. TEE was performed in all the patients who were categorized into two groups according to their left atrial appendage (LAA) function. A total of 120 of the 249 AF patients had LAA dysfunction. Univariate and multivariate logistic regression was conducted to assess the independent factors that correlated with the LAA dysfunction. Different predictive models for the LAA dysfunction were compared with the receiver operating characteristic (ROC) curve. The final ROC curve on the development and validation datasets was drawn based on the calculation of each area under the curves (AUC). Univariate and multivariate analysis showed that the peak left atrial strain (PLAS) was the most significant factor that correlated with the LAA dysfunction. PLAS did not show inferiority amongst all the models and revealed strong discrimination ability on both the development and validation datasets with AUC 0.818 and 0.817. Our study showed that a decrease in PLAS is independently associated with LAA dysfunction in the AF patients.


Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Suman S Kuppahally ◽  
Robert S Oakes ◽  
Eric N Fish ◽  
Eugene Kholmovski ◽  
Sathya Vijayakumar ◽  
...  

Introduction: The extent of left atrial (LA) wall fibrosis detected by delayed enhancement (DE)-cardiac MRI prior to catheter ablation of atrial fibrillation (AF) appears to predict procedural success. However, it is currently unknown how the degree of fibrosis affects atrial mechanical function. Methods: Prior to catheter ablation of AF, 31 patients underwent DE-CMRI and 2-dimensional transthoracic echocardiography. 3D segmentation of LA was performed and the degree of fibrosis was determined using a semi-automated quantification algorithm. Longitudinal mid-septal and mid-lateral LA wall velocity, strain and strain rate were measured during ventricular systole from the apical 4-chamber view by velocity vector imaging. Results : There was greater percent of fibrosis as LA maximum (R = 0.4, p = 0.05) and minimum (R=0.52, p = 0.008) volumes increased. Figure shows examples of DE-CMRI and strain curves (C) for two patients: Patient 1(A) with mild fibrosis and patient 2 (B) with extensive fibrosis. Patient 1 shows much larger strain than patient 2. Larger LA volumes correlated inversely with maximal LA mid-lateral systolic wall strain (p < 0.005). The percent fibrosis also correlated inversely with maximal LA mid-lateral systolic wall strain (R=0.56, p < 0.005) and the systolic strain rate (R = 0.58, p = 0.002). Conclusion: LA strain and strain rate can be assessed using standard echocardiographic gray scale images. LA strain is related to both atrial volumes and fibrosis, which are markers of atrial disease progression. This relationship may represent changes in the properties of LA substrate. These novel imaging approaches may be helpful in predicting outcomes in patients with AF.


2011 ◽  
Vol 24 (5) ◽  
pp. 513-519 ◽  
Author(s):  
Jhih-Yuan Shih ◽  
Wei-Chuan Tsai ◽  
Yao-Yi Huang ◽  
Yen-Wen Liu ◽  
Chih-Chan Lin ◽  
...  

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Ying Shan ◽  
Grace Lin ◽  
Toshinori Yuasa ◽  
Fletcher A Miller ◽  
Steve R Ommen ◽  
...  

Background: Atrial fibrillation (AF) is common in HCM yet the mechanisms are poorly understood but are likely secondary to either the consequences of left atrial structural remodeling (LASR) or myopathy, or triggers arising from pulmonary and other thoracic veins. The presence and severity of LASR as characterized by left atrial strain (LA ϵ), and its relationship to AF in HCM, has not been determined. Therefore, we measured LA ϵ and strain rate (SR) in Pts with HCM both with (AF+) and without (AF−) prior AF and compared these measures to those in age and gender matched controls without HCM or AF. Methods: Two-dimensional speckle-derived LA longitudinal peak ϵ, SR during systole (SR S ), early (SR E ) and late diastole (SR A ) were measured at the basal and mid portions of the lateral, septal, and posterior LA walls using Vector Velocity Imaging during sinus rhythm and were averaged. Results: Mean age of Pts in each of the matched groups was 56 ± 2 years (16 males; 59%). Significant left ventricular outflow tract obstruction was present in all Pts with HCM. Diastolic dysfunction was similar in both HCM groups and worse when compared to controls. Peak LA 3 , SR S , SR E , and SR A for each group is shown (table 1 ). HCM was associated with significantly lower LA ϵ and SR compared to controls. Although LA size was increased in Pts with HCM when compared to controls there was no correlation between LA size and ϵ or SR (p>0.05 for all). No differences in LA ϵ and SR were found between AF+ versus AF− Pts. Conclusion: HCM is associated with LASR as determined by decreased LA ϵ and SR. However, LA ϵ and SR were similar in AF+ versus AF− Pts suggesting that the occurrence of AF in HCM is not due to LASR alone. Table 1. Left Atrial Strain and Strain Rate in Hypertrophic Cardiomyopathy


2019 ◽  
Vol 131 (7-8) ◽  
pp. 156-164 ◽  
Author(s):  
Monika Jankajova ◽  
Lucia Kubikova ◽  
Gabriel Valocik ◽  
Peter Candik ◽  
Peter Mitro ◽  
...  

2010 ◽  
Vol 3 (3) ◽  
pp. 231-239 ◽  
Author(s):  
Suman S. Kuppahally ◽  
Nazem Akoum ◽  
Nathan S. Burgon ◽  
Troy J. Badger ◽  
Eugene G. Kholmovski ◽  
...  

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