Association of Decreased Left Atrial Strain and Strain Rate with Stroke in Chronic Atrial Fibrillation

2011 ◽  
Vol 24 (5) ◽  
pp. 513-519 ◽  
Author(s):  
Jhih-Yuan Shih ◽  
Wei-Chuan Tsai ◽  
Yao-Yi Huang ◽  
Yen-Wen Liu ◽  
Chih-Chan Lin ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Strain Rate ◽  
Left Atrial ◽  
Chronic Atrial Fibrillation ◽  
Left Atrial Strain ◽  
Strain And Strain Rate ◽  
Atrial Strain

scholarly journals ASSOCIATION OF DECREASED LEFT ATRIAL STRAIN AND STRAIN RATE WITH STROKE IN CHRONIC ATRIAL FIBRILLATION

2010 ◽  
Vol 55 (10) ◽  
pp. A93.E879
Author(s):  
Jhih-Yuan Shih ◽  
Wei-Chuan Tsai ◽  
Yao-Yi Huang ◽  
Yen-Wen Liu ◽  
Chih-Chan Lin ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Strain Rate ◽  
Left Atrial ◽  
Chronic Atrial Fibrillation ◽  
Left Atrial Strain ◽  
Strain And Strain Rate ◽  
Atrial Strain

Abstract 5664: Left Atrial Strain In Patients With Atrial Fibrillation: Relationship To Fibrosis By Delayed Enhancement-MRI

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Suman S Kuppahally ◽  
Robert S Oakes ◽  
Eric N Fish ◽  
Eugene Kholmovski ◽  
Sathya Vijayakumar ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Strain Rate ◽  
Left Atrial ◽  
Delayed Enhancement ◽  
Left Atrial Strain ◽  
Chamber View ◽  
Strain And Strain Rate ◽  
Procedural Success ◽  
Atrial Strain

Introduction: The extent of left atrial (LA) wall fibrosis detected by delayed enhancement (DE)-cardiac MRI prior to catheter ablation of atrial fibrillation (AF) appears to predict procedural success. However, it is currently unknown how the degree of fibrosis affects atrial mechanical function. Methods: Prior to catheter ablation of AF, 31 patients underwent DE-CMRI and 2-dimensional transthoracic echocardiography. 3D segmentation of LA was performed and the degree of fibrosis was determined using a semi-automated quantification algorithm. Longitudinal mid-septal and mid-lateral LA wall velocity, strain and strain rate were measured during ventricular systole from the apical 4-chamber view by velocity vector imaging. Results : There was greater percent of fibrosis as LA maximum (R = 0.4, p = 0.05) and minimum (R=0.52, p = 0.008) volumes increased. Figure shows examples of DE-CMRI and strain curves (C) for two patients: Patient 1(A) with mild fibrosis and patient 2 (B) with extensive fibrosis. Patient 1 shows much larger strain than patient 2. Larger LA volumes correlated inversely with maximal LA mid-lateral systolic wall strain (p < 0.005). The percent fibrosis also correlated inversely with maximal LA mid-lateral systolic wall strain (R=0.56, p < 0.005) and the systolic strain rate (R = 0.58, p = 0.002). Conclusion: LA strain and strain rate can be assessed using standard echocardiographic gray scale images. LA strain is related to both atrial volumes and fibrosis, which are markers of atrial disease progression. This relationship may represent changes in the properties of LA substrate. These novel imaging approaches may be helpful in predicting outcomes in patients with AF.

Abstract 2250: Is Atrial Fibrillation in Hypertrophic Cardiomyopathy Due to Left Atrial Structural Remodeling as Determined by Speckle-Derived Atrial Strain Imaging?

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Ying Shan ◽  
Grace Lin ◽  
Toshinori Yuasa ◽  
Fletcher A Miller ◽  
Steve R Ommen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Hypertrophic Cardiomyopathy ◽  
Strain Rate ◽  
Left Atrial ◽  
Ventricular Outflow Tract ◽  
Left Ventricular ◽  
Left Atrial Strain ◽  
Structural Remodeling ◽  
Strain And Strain Rate ◽  
Atrial Strain

Background: Atrial fibrillation (AF) is common in HCM yet the mechanisms are poorly understood but are likely secondary to either the consequences of left atrial structural remodeling (LASR) or myopathy, or triggers arising from pulmonary and other thoracic veins. The presence and severity of LASR as characterized by left atrial strain (LA ϵ), and its relationship to AF in HCM, has not been determined. Therefore, we measured LA ϵ and strain rate (SR) in Pts with HCM both with (AF+) and without (AF−) prior AF and compared these measures to those in age and gender matched controls without HCM or AF. Methods: Two-dimensional speckle-derived LA longitudinal peak ϵ, SR during systole (SR S ), early (SR E ) and late diastole (SR A ) were measured at the basal and mid portions of the lateral, septal, and posterior LA walls using Vector Velocity Imaging during sinus rhythm and were averaged. Results: Mean age of Pts in each of the matched groups was 56 ± 2 years (16 males; 59%). Significant left ventricular outflow tract obstruction was present in all Pts with HCM. Diastolic dysfunction was similar in both HCM groups and worse when compared to controls. Peak LA 3 , SR S , SR E , and SR A for each group is shown (table 1 ). HCM was associated with significantly lower LA ϵ and SR compared to controls. Although LA size was increased in Pts with HCM when compared to controls there was no correlation between LA size and ϵ or SR (p>0.05 for all). No differences in LA ϵ and SR were found between AF+ versus AF− Pts. Conclusion: HCM is associated with LASR as determined by decreased LA ϵ and SR. However, LA ϵ and SR were similar in AF+ versus AF− Pts suggesting that the occurrence of AF in HCM is not due to LASR alone. Table 1. Left Atrial Strain and Strain Rate in Hypertrophic Cardiomyopathy

scholarly journals Left Atrial Strain and Strain Rate in Patients With Paroxysmal and Persistent Atrial Fibrillation

2010 ◽  
Vol 3 (3) ◽  
pp. 231-239 ◽  
Author(s):  
Suman S. Kuppahally ◽  
Nazem Akoum ◽  
Nathan S. Burgon ◽  
Troy J. Badger ◽  
Eugene G. Kholmovski ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Strain Rate ◽  
Left Atrial ◽  
Persistent Atrial Fibrillation ◽  
Left Atrial Strain ◽  
Strain And Strain Rate ◽  
Atrial Strain

scholarly journals Do left atrial strain and strain rate reflect intrinsic atrial function, or are they determined by left ventricular function?

2015 ◽  
pp. 539-548 ◽  
Author(s):  
Andrei Dumitru Margulescu ◽  
Emma Rees ◽  
Rose-Marie Coulson ◽  
Aled D. Rees ◽  
Dragos Vinereanu ◽  
...  
Keyword(s):  
Left Ventricular Function ◽  
Strain Rate ◽  
Ventricular Function ◽  
Left Atrial ◽  
Left Ventricular ◽  
Atrial Function ◽  
Left Atrial Strain ◽  
Strain And Strain Rate ◽  
Atrial Strain
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