Prognostic value of serum galactomannan in mixed ICU patients: a retrospective observational study

2014 ◽  
Vol 46 (3) ◽  
pp. 145-154 ◽  
Author(s):  
Suzanne Teering ◽  
Annelies Verreth ◽  
Anneleen Peeters ◽  
Niels Van Regenmortel ◽  
Inneke De Laet ◽  
...  
Critical Care ◽  
2012 ◽  
Vol 16 (S1) ◽  
Author(s):  
S Teering ◽  
A Verreth ◽  
W Verlinden ◽  
J Jacobs ◽  
S Pilate ◽  
...  

Cureus ◽  
2022 ◽  
Author(s):  
Chukwuemeka Umeh ◽  
Laura Tuscher ◽  
Sobiga Ranchithan ◽  
Kimberly Watanabe ◽  
Rahul Gupta

2021 ◽  
pp. 084653712110028
Author(s):  
Vibeeshan Jegatheeswaran ◽  
Michael W. K. Chan ◽  
Sumon Chakrabarti ◽  
Adrian Fawcett ◽  
Yingming Amy Chen

Purpose: Coronavirus disease (COVID-19) has been associated with neurologic sequelae and neuroimaging abnormalities in several case series previously. In this study, the neuroimaging findings and clinical course of adult patients admitted with COVID-19 to a tertiary care hospital network in Canada were characterized. Methods: This is a retrospective observational study conducted at a tertiary hospital network in Ontario, Canada. All adult patients with PCR-confirmed COVID-19 admitted from February 1, 2020 to July 22, 2020 who received neuroimaging related to their COVID-19 admission were included. CT and MR images were reviewed and categorized by fellowship-trained neuroradiologists. Demographic and clinical data were collected and correlated with imaging findings. Results: We identified 422 patients admitted with COVID-19 during the study period. 103 (24.4%) met the inclusion criteria and were included: 30 ICU patients (29.1%) and 73 non-ICU patients (70.9%). A total of 198 neuroimaging studies were performed: 177 CTs and 21 MRIs. 17 out of 103 imaged patients (16.8%) had acute abnormalities on neuroimaging: 10 had macrohemorrhages (58.8%), 9 had acute ischemia (52.9%), 4 had SWI abnormalities (23.5%), and 1 had asymmetric sulcal effacement suggesting possible focal encephalitis (5.8%). ICU patients were more likely to have positive neuroimaging findings, more specifically acute ischemia and macrohemorrhages ( P < 0.05). Macrohemorrhages were associated with increased mortality ( P < 0.05). Conclusion: Macrohemorrhages, acute ischemia and SWI abnormalities were the main neuroimaging abnormalities in our cohort of hospitalized COVID-19 patients. Acute ischemia and hemorrhage were associated with worse clinical status.


Aging ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 4794-4810
Author(s):  
Wang Zhang ◽  
Ling Sang ◽  
Jiaran Shi ◽  
Ming Zhong ◽  
Li Jiang ◽  
...  

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.


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