scholarly journals Evaluation of the healing progress of phlegmon related to type 2 diabetes treated with the local hyperbaric oxygen therapy

2018 ◽  
Vol 24 (3) ◽  
pp. 93-97 ◽  
Author(s):  
Jarosław Pasek ◽  
Grzegorz Cieślar ◽  
Aleksander Sieroń
2018 ◽  
Vol 12 (1) ◽  
pp. 80-85 ◽  
Author(s):  
Sarah Perren ◽  
Alfred Gatt ◽  
Nikolaos Papanas ◽  
Cynthia Formosa

Background and Aims: Several treatment modalities and protocols for ischaemic foot ulcers are available. However, little consensus exists on optimal treatment. The aim of this study was to compare Standard Wound Care (SWC) alone vs. SWC with adjunct hyperbaric oxygen therapy (HBOT) in the treatment of ischaemic Diabetic Foot Ulcers (DFUs). Patients and Methods: Twenty-six patients with Type 2 Diabetes Mellitus (T2DM) presenting with a newly diagnosed ischaemic foot ulcer were included. These were divided into group A (SWC with adjunct HBOT) and group B (SWC only). Participants were followed every week for 4 weeks and their ulcers were measured for their surface area and depth to assess any change in wound size. Results: Both treatment arms succeeded in reducing ulcer area and depth (p<0.001). However, ulcer area (p<0.001) and depth (p<0.001) exhibited superior improvement in group A. Conclusion : Adjunctive HBOT appears to improve wound healing in ischaemic DFUs and merits further study.


2022 ◽  
Vol 2022 ◽  
pp. 1-3
Author(s):  
D. Ricard-Gauthier ◽  
M.-A. Panchard ◽  
D. E. Huber

We hereby report the case of a 66-year-old obese patient (BMI 30) with type 2 diabetes, who presented a chronic vulvar lesion on the left labia majora following surgical drainage of an abscess. After multiple unsuccessful treatments by antibiotics and local wound care, we proposed a trial of hyperbaric oxygen therapy (HBOT). The patient fully recovered after 54 sessions at 2.5 ATA, 95 minutes each. HBOT has been studied for perineal lesion such as skin atrophy or necrosis caused by irradiation but not for vulvar nonhealing chronic lesions in the case of impaired vascularization caused by diabetes. This case is, to our knowledge, one of the first publications about the healing boost of HBOT in chronic vulvar wounds due to vascular impairment.


2013 ◽  
Vol 7 ◽  
pp. e5-e6
Author(s):  
Leonie Heilbronn ◽  
David Wilkinson ◽  
Mirjam Nolting ◽  
Mohd Mahadi ◽  
Ian Chapman

2007 ◽  
Vol 135 (11-12) ◽  
pp. 669-671 ◽  
Author(s):  
Predrag Brkic ◽  
Ana Mitrovic ◽  
Miodrag Rakic ◽  
Mirko Grajic ◽  
Tomislav Jovanovic

Introduction Phenotype match inherited by genes is in most cases present in monozygotic twins. Their phenotypic resemblance is unfortunately characterized by strong susceptibility for the development of chronic non-infectious diseases. One of the most common non-infectious chronic diseases that are phenotipically represented in twins is diabetes mellitus. Genetic imbalance is, in most cases, placed in 2, 3, 7, 8, 11, 12, 19 and 20 chromosomal pair of the human genome. CASE OUTLINE This study describes a pair of monozygotic twins, aged 54, who were diagnosed for diabetes type 2 ten years earlier. The first patient had trophic changes of muscles and skin tissues of the lower limb, and a necrotic wound on his right leg tibial region with the claudication distance of 50 m. After arteriography, he was referred by a vascular surgeon for hyperbaric oxygen therapy (HBO). HBO protocol implied 70 min. application of 100% oxygen at 2.5 absolute atmospheres. After the first series of HBO therapies consisting of 20 HBO treatments, claudication was eliminated and the necrotic wound healed. Next, surgical aortofemoral bypass was done. During the second HBO treatment, his monozygotic twin brother presented with angiopathic changes due to diabetes. In both patients, biochemical parameters corresponded to the expected level for diabetes type 2 imbalance, and the localization of the chromosomal defect (placed on 3, 11 and 19 chromosomal pair) was also in accordance with the respective disorder. After they were included into next 10 HBO treatments, Doppler imaging of the major arteries of limbs revealed normal findings. Conclusion Identical genetic impairment in monozygotic twins can lead to identical somatic changes with resultant consequences. HBO treatment of such patients associated with other therapeutic procedures (conducted by diabetologist, vascular surgeon and physiatrist) can postpone or prevent irreversible changes occurring due to blood vessel disorders.


Sign in / Sign up

Export Citation Format

Share Document