scholarly journals NMR Spectroscopy for Studying Interactions of Bioactive Molecules

Author(s):  
Predrag Novak ◽  
Tomislav Jednačak
2018 ◽  
Vol 14 ◽  
pp. 1446-1451 ◽  
Author(s):  
Dandan Li ◽  
Naoya Oku ◽  
Atsumi Hasada ◽  
Masafumi Shimizu ◽  
Yasuhiro Igarashi

Exploration of rhizobacteria of the genus Burkholderia as an under-tapped resource of bioactive molecules resulted in the isolation of two new antimicrobial 2-alkyl-4-quinolones. (E)-2-(Hept-2-en-1-yl)quinolin-4(1H)-one (1) and (E)-2-(non-2-en-1-yl)quinolin-4(1H)-one (3) were isolated from the culture broth of strain MBAF1239 together with four known alkylquinolones (2 and 4–6), pyrrolnitrin (7), and BN-227 (8). The structures of 1 and 3 were unambiguously characterized using NMR spectroscopy and mass spectrometry. Compounds 1–8 inhibited the growth of the marine bacterium Tenacibaculum maritimum, an etiological agent of skin ulcers in marine fish, offering new opportunities to develop antibacterial drugs for fish farming.


1999 ◽  
Vol 96 (12) ◽  
pp. 1739-1744 ◽  
Author(s):  
T. S. UNTIDT, S. J. GLASER, C. GRIESIN

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
A Booker ◽  
D Frommenwiler ◽  
C Umealajekwu ◽  
D Johnston ◽  
E Reich ◽  
...  

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
S Groscurth ◽  
T Kühn ◽  
P Kessler ◽  
V Rukachaisirikul

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