Virtual File Systems for Dynamic Content in Digital Production Workflows: A Novel Approach to Integration of Video Applications and MAM Based Archives

Author(s):  
Dmitry Klimov ◽  
Jan Weigner
2019 ◽  
Vol 2019 ◽  
pp. 1-19
Author(s):  
Z. Yu ◽  
Y. Zuo ◽  
W. C. Xiong

Software transactional memory is an effective mechanism to avoid concurrency bugs in multithreaded programs. However, two problems hinder the adoption of such traditional systems in the wild world: high human cost for equipping programs with transaction functionality and low compatibility with I/O calls and conditional variables. This paper presents Convoider to solve these problems. By intercepting interthread operations and designating code among them as transactions in each thread, Convoider automatically transactionalizes target programs without any source code modification and recompiling. By saving/restoring stack frames and CPU registers on beginning/aborting a transaction, Convoider makes execution flow revocable. By turning threads into processes, leveraging virtual memory protection and customizing memory allocation/deallocation, Convoider makes memory manipulations revocable. By maintaining virtual file systems and redirecting I/O operations onto them, Convoider makes I/O effects revocable. By converting lock/unlock operations to no-ops, customizing signal/wait operations on condition variables, and committing memory changes transactionally, Convoider makes deadlocks, data races, and atomicity violations impossible. Experimental results show that Convoider succeeds in transparently transactionalizing twelve real-world applications with averagely incurring only 28% runtime overhead and perfectly avoid 94% of thirty-one concurrency bugs used in our experiments. This study can help efficiently transactionalize legacy multithreaded applications and effectively improve the runtime reliability of them.


Author(s):  
Sasi Palarivattom ◽  
Kayamkulam Kochunni

In recent years, much research has been devoted to the evaluation of checksums; nevertheless, few have simulated the construction of RPCs. In this position paper, we prove the development of robots. We motivate a novel approach for the improvement of hash tables (Intwist), which we use to prove that evolutionary programming can be made wireless, cacheable, and semantic. In conclusion, our experiences with in twist and real-time archetypes show that the Turing machine and journaling file systems can interfere to overcome this quagmire. We considered how gigabit switches can be applied to the construction of operating systems. in twist has set a precedent for signed algorithms, and we expect that leading analysts will explore our system for years to come. One potentially profound shortcoming of in twist is that it might allow Internet QoS; we plan to address this in future work.


2014 ◽  
Vol 7 (6) ◽  
pp. 7427-7459
Author(s):  
D. C. Wong ◽  
C. E. Yang ◽  
J. S. Fu ◽  
K. Wong ◽  
Y. Gao

Abstract. Data intensive simulations are often limited by their I/O performance, and novel techniques need to be developed in order to overcome this limitation. The software package, pnetCDF which works with parallel file systems, was developed to address this issue by providing parallel I/O capability. This study examines the performance of a novel approach which performs data aggregation along either row or column dimension of MPI processes on a spatially decomposed domain, and then applies the pnetCDF parallel I/O paradigm. The test was done with three different domain sizes which represent small, moderately large, and large data domains, using a small-scale Community Multi-scale Air Quality model (CMAQ) mock-up code. The examination includes comparing I/O performance with traditional serial I/O technique, straight application of pnetCDF, and the data aggregation along row and column dimension before applying pnetCDF. After the comparison, "optimal" I/O configurations of this novel approach were quantified. Data aggregation along the row dimension (pnetCDFcr) works better than along the column dimension (pnetCDFcc) although it may perform slightly worse than the straight pnetCDF method with a small number of processors. When the number of processors becomes larger, pnetCDFcr out performs pnetCDF significantly. If the number of processors keeps increasing, pnetCDF reaches a point where the performance is even worse than the serial I/O technique. This new technique has also been tested for a real application where it performs two times better than the straight pnetCDF paradigm.


2015 ◽  
Vol 50 ◽  
pp. 590-595 ◽  
Author(s):  
Miss. J. Vini ◽  
Rachel Nallathamby ◽  
C.R. Rene Robin

2015 ◽  
Vol 126 (14) ◽  
pp. 28-33
Author(s):  
Divya Diwakar ◽  
Sushil Chaturvedi ◽  
S.K. Shrivastava

2019 ◽  
Vol 476 (24) ◽  
pp. 3705-3719 ◽  
Author(s):  
Avani Vyas ◽  
Umamaheswar Duvvuri ◽  
Kirill Kiselyov

Platinum-containing drugs such as cisplatin and carboplatin are routinely used for the treatment of many solid tumors including squamous cell carcinoma of the head and neck (SCCHN). However, SCCHN resistance to platinum compounds is well documented. The resistance to platinum has been linked to the activity of divalent transporter ATP7B, which pumps platinum from the cytoplasm into lysosomes, decreasing its concentration in the cytoplasm. Several cancer models show increased expression of ATP7B; however, the reason for such an increase is not known. Here we show a strong positive correlation between mRNA levels of TMEM16A and ATP7B in human SCCHN tumors. TMEM16A overexpression and depletion in SCCHN cell lines caused parallel changes in the ATP7B mRNA levels. The ATP7B increase in TMEM16A-overexpressing cells was reversed by suppression of NADPH oxidase 2 (NOX2), by the antioxidant N-Acetyl-Cysteine (NAC) and by copper chelation using cuprizone and bathocuproine sulphonate (BCS). Pretreatment with either chelator significantly increased cisplatin's sensitivity, particularly in the context of TMEM16A overexpression. We propose that increased oxidative stress in TMEM16A-overexpressing cells liberates the chelated copper in the cytoplasm, leading to the transcriptional activation of ATP7B expression. This, in turn, decreases the efficacy of platinum compounds by promoting their vesicular sequestration. We think that such a new explanation of the mechanism of SCCHN tumors’ platinum resistance identifies novel approach to treating these tumors.


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