The Impact of Nonlinear Editing on the Post-Production Process

SMPTE Journal ◽  
1996 ◽  
Vol 105 (10) ◽  
pp. 641-646 ◽  
Author(s):  
Michael F. Korpi ◽  
Corey P. Carbonara ◽  
Vincent E. Young
Vaccines ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 3
Author(s):  
Zoltán Kis ◽  
Cleo Kontoravdi ◽  
Robin Shattock ◽  
Nilay Shah

To overcome pandemics, such as COVID-19, vaccines are urgently needed at very high volumes. Here we assess the techno-economic feasibility of producing RNA vaccines for the demand associated with a global vaccination campaign. Production process performance is assessed for three messenger RNA (mRNA) and one self-amplifying RNA (saRNA) vaccines, all currently under clinical development, as well as for a hypothetical next-generation saRNA vaccine. The impact of key process design and operation uncertainties on the performance of the production process was assessed. The RNA vaccine drug substance (DS) production rates, volumes and costs are mostly impacted by the RNA amount per vaccine dose and to a lesser extent by the scale and titre in the production process. The resources, production scale and speed required to meet global demand vary substantially in function of the RNA amount per dose. For lower dose saRNA vaccines, global demand can be met using a production process at a scale of below 10 L bioreactor working volume. Consequently, these small-scale processes require a low amount of resources to set up and operate. RNA DS production can be faster than fill-to-finish into multidose vials; hence the latter may constitute a bottleneck.


Author(s):  
José Arredondo ◽  
Juan F. Aguirre‐Medina ◽  
José S. Meza ◽  
Jorge Cancino ◽  
Francisco Díaz‐Fleischer

2011 ◽  
Vol 314-316 ◽  
pp. 1944-1947 ◽  
Author(s):  
Jozef Maščeník ◽  
Stefan Gaspar

Production of components, necessary for the construction of the machine resp. or device is a demanding manufacturing process. One of the possibilities of increasing efficiency and production quality is the introduction of unconventional technologies to the production process. Knowing the dependence of the impact of non-conventional technologies on the mechanical properties of products and their subsequent verification is an important aspect when designing and manufacturing them. The article deals with the impact of used unconventional technology, that means laser, plasma and water jet on the roughness of a cutting edge and microhardness of material S 355 J2 G3.


2021 ◽  
Vol 894 (1) ◽  
pp. 012004
Author(s):  
S Hartini ◽  
B S Ramadan ◽  
R Purwaningsih ◽  
S Sumiyati ◽  
M A A Kesuma

Abstract Tofu contains various substances that are very good when consumed to improve people’s nutrition. In addition, tofu also has good taste. The problem is that the tofu production process produces products and non-product outputs in the form of waste that is very dangerous if directly disposed of in the environment. The BOD5 content of tofu small and medium-sized enterprises (SMEs) in Sugihmanik Village ranged from 3,667-4,933 mg/L and COD 7,668-9,736 mg/L. At the same time, the TSS values ranged from 701-1,189 mg/L. The BOD5 value in the river water content is 367 mg/L. It greatly exceeds the set Threshold Value. This study aims to measure the environmental impact using Life Cycle Assessment (LCA). LCA can identify the impact of each activity based on the impact category to identify the processes that contribute significantly to damaging the environment. This study found that the cooking and frying process had the highest impact, where the climate change category was the largest. Wastewater treatment plants, biogas from the biodigester as a substitute for electricity for water pumps, rice husks, and corn cobs are expected to reduce environmental impacts. The first section in your paper


2019 ◽  
Vol 11 (15) ◽  
pp. 4254 ◽  
Author(s):  
Munodawafa ◽  
Johl

Increased greenhouse gas (GHG) emissions in the past decades have created concerns about the environment. To stymie global warming and the deterioration of the natural environment, global CO2 emissions need to reach approximately 1.3 tons per capita by 2050. However, in Malaysia, CO2 output per capita—driven by fossil fuel consumption and energy production—is expected to reach approximately 12.1 tons by the year 2020. GHG mitigation strategies are needed to address these challenges. Cleaner production, through eco-innovation, has the potential to arrest CO2 emissions and buttress sustainable development. However, the cleaner production process has been hampered by lack of complete data to support decision making. Therefore, using the resource-based view, a preliminary study consisting of energy and utility firms is undertaken to understand the impact of big data analytics towards eco-innovation. Linear regression through SPSS Version 24 reveals that big data analytics could become a strong predictor of eco-innovation. This paper concludes that information and data are key inputs, and big data technology provides firms the opportunity to obtain information, which could influence its production process—and possibly help arrest increasing CO2 emissions.


DEDIKASI ◽  
2019 ◽  
Vol 21 (1) ◽  
Author(s):  
I Gede Nyoman Suta Waisnawa ◽  
I Made Sudana ◽  
Ida Bagus Swaputra

The results of the implementation of ergonomics in deco and shop camps were specifically focused onimproving work facilities, workplaces, layouts, work procedures, and work environment, increasing workers'comfort in conducting production activities, and utilizing space so that the production process becomes safe andflexible. Outputs that have been achieved included (1) workstations arranged in an efficient material flow layoutsupported by adequate work tools so it can optimize the achievement of production targets, (2) improvement of theprocess and procedures for completing work, (3) improvement and savings in the use of materials, machinery/tools,and humans, (4) utilization of humans’ efforts, (5) improving workspace arrangements that can provide acomfortable and safe working environment. The implementation of participatory ergonomics production capacitycan reach 456 pieces/year and shop production as many as 24 pieces/year, for example; tiger, bear, eagle, cow headetc. After the ergonomic intervention, the production capacity increased to 52 pieces/year. The impact of thisprogram was an increase in production capacity of Ari deco craftsmen (67.5%) and Kubu shop craftsmen (46.15%),while business partners' turnover was around 69.9%.


2017 ◽  
Vol 15 (3) ◽  
pp. 353
Author(s):  
Bojan Boshevski ◽  
Ile Mircheski

This paper presents the development process of a bicycle helmet through individual research, creation, presentation and analysis of the results of the most important product development stages. The quality of the development and manufacturing process of the protective equipment for extreme sports is an imperative for a successful product and its flawless function. The design of the bicycle helmet is made following the rules of the design in order to create a well-founded and functional product. After creating design sketches, a virtual prototype was developed in "SolidWorks" using the required ergonomic dimensions. 3D printed model of the human head with adapted ergonomic dimensions and the designed bicycle helmet was developed in order to verify the applied ergonomic measures. The virtual model will be used as an input in the finite element analysis of the helmet impact test based on the EN1078 standard and the aerodynamic simulations executed in "SolidWorks Simulation and Flow Simulation", for verification of the impact and aerodynamic properties. Virtual testing of aerodynamic features and the ability of the bicycle helmet to allow ventilation of the user's head indicate that the helmet performs its function in the desired way. Also, the virtual prototype will be used for the production process simulation in "SolidWorks Plastics" in order to analyze the production of the bicycle helmet. The polycarbonate helmet outer shell is subject to a number of simulations for the sake of analyzing the production process in order to obtain the desired characteristics of the polycarbonate outer shell and to avoid the disadvantages that occur in the manufacturing process. The main goal of this paper is to develop a safety bicycle helmet with improved ergonomic, validation of impact, aerodynamic characteristics and production process in order to produce a high quality product for mass use.


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