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1939 ◽  
Vol 33 (7) ◽  
pp. 18-25 ◽  
Author(s):  
Peter C. Goldmark
Psychiatry ◽  
2020 ◽  
Vol 18 (4) ◽  
pp. 16-25
Author(s):  
N. S. Karpova ◽  
O. S. Brusov ◽  
I. V. Oleichik ◽  
M. I. Faktor ◽  
N. S. Levchenko ◽  
...  

Background: currently, it has been proven that the pathogenesis of endogenous mental disorders is associated with the process of neuroinflammation in the brain of patients. It is also known that chronic neuroinflammation, accompanied by a violation the permeability of the blood-brain barrier. It is accompanied by the activation of platelets that generate procoagulant microparticles, which leads to a disturbance of the hemostasis system, causing an increase in blood clotting in patients. Objective: to investigate the dynamics of procoagulant activity of blood in patients with endogenous mental disorders before and after psychopharmacotherapy.Patients and methods: the study included 185 patients aged 16 to 64 years with the following mental disorders: schizophrenia with attack-like/attack-progressive/continuous type of course (F20.00–2), affective disease (F31.1–5; F32.0–3; F33.0–3), schizotypal disorder with affective fluctuations (F21.3–4). The thrombodynamic test (TD) was performed on T-2 Trombodynamis device according to the manufacturer’s instructions (Hemacore LLC, Moscow, Russia). All patients received standard pharmacotherapy according to their condition.Results: a significant decrease of procoagulant activity of spontaneous clots in the patients’ blood after psychopharmacological treatment is observed. Our data on the positive dynamics of changes in the values of TD test’s indicators in most of the examined patients suggest that a decrease in the coagulation activity of the patients’ blood as a result of treatment may be associated with the anti- inflammatory effect of antipsychotics and antidepressants.Conclusion: for the first time, it was shown that there is a positive dynamic in changing the values of the main parameters of the TD test in most patients with endogenous mental diseases. The results of TD tests can be the basis for monitoring the response to therapy.


Author(s):  
James Whitehead

The introductory chapter discusses the popular image of the ‘Romantic mad poet’ in television, film, theatre, fiction, the history of literary criticism, and the intellectual history of the twentieth century and its countercultures, including anti-psychiatry and psychoanalysis. Existing literary-historical work on related topics is assessed, before the introduction goes on to suggest why some problems or difficulties in writing about this subject might be productive for further cultural history. The introduction also considers at length the legacy of Michel Foucault’s Folie et Déraison (1961), and the continued viability of Foucauldian methods and concepts for examining literary-cultural representations of madness after the half-century of critiques and controversies following that book’s publication. Methodological discussion both draws on and critiques the models of historical sociology used by George Becker and Sander L. Gilman to discuss genius, madness, deviance, and stereotype in the nineteenth century. A note on terminology concludes the introduction.


Author(s):  
Tina Pippin

The Rapture is the sudden and hoped for event of the second coming of Jesus Christ in the clouds to raise true Christian believers to heaven. American popular culture has played with this scenario in a variety of genres (e.g., television, film, novels), most often in a satirical way. From the faith perspective, the Rapture is a major theme in Christian fiction (the Left Behind series) and follows a timeline of political and historical events. Representations of the Rapture in popular culture often reflect the current political climate and the psychological anxiety, isolation, and sense of persecution of believers.


2011 ◽  
Vol 71-78 ◽  
pp. 1933-1937
Author(s):  
Jia Yun Xu ◽  
Ji Chen ◽  
Xian Wei Qu ◽  
Wen Kai Gong

This paper takes a Chinese Changjiang River highway bridge as engineering background, and a kind of continuous three-dimensional (vertical, lateral and torsion)controllers which can apply in the large span cable-stayed bridge is presented. The controllers can control vertical, lateral and torsional response of bridge wind-induced vibration at the same time. Through comparative wind tunnel test of the bridge model with and without controllers, some important conclusions are made as follows: when the continuous three-dimensional controllers are installed on the bridge model, its flutter critical wind speed increases significantly (mostly increases 33.36%); Meanwhile, there is a certain degree of reduction in its RMS values of vertical, lateral and torsional angular displacement response.


1993 ◽  
Vol 76 (4) ◽  
pp. 510-518 ◽  
Author(s):  
Michael K. Shrout ◽  
Brad J. Potter ◽  
H. Michael Yurgalavage ◽  
Charles F. Hildebolt ◽  
Michael W. Vannier

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