scholarly journals Laboratory comparison of stool processing methods for Xpert® Ultra

2021 ◽  
Vol 11 (2) ◽  
pp. 55-57
Author(s):  
C. L. Jasumback ◽  
Q. Dlamini ◽  
J. Kahari ◽  
G. Maphalala ◽  
M. G. Dlamini ◽  
...  
Keyword(s):  
Error Rate ◽  
Healthy Adult ◽  
Disease Diagnosis ◽  
Invasive Procedures ◽  
Bacille Calmette Guerin ◽  
Processing Methods ◽  
Specific Symptoms ◽  
Relative Detection

TB disease diagnosis in children is difficult due to non-specific symptoms, paucibacillary disease and the need for invasive procedures to obtain diagnostic specimens. In many settings, these specimens are simply not collected and therefore stool, easily obtained, has emerged as a promising specimen for the diagnosis of child TB. In this study, stool from a healthy adult was spiked with known concentrations of bacille Calmette-Guérin vaccine and tested using the Xpert® Ultra assay to determine the relative detection and error rate associated with four different published stool processing methods.

Design of an Android-Based Tropical Disease Diagnosis Expert System Design Using a Combined Method of Forward Chanining and Backward Chaining

2015 ◽  
Vol 1 (1) ◽  
pp. 43-50
Author(s):  
Muhammad Fahmi Hidayah
Keyword(s):  
Expert System ◽  
Expert Systems ◽  
Disease Diagnosis ◽  
Reference Book ◽  
Combined Method ◽  
Specific Domain ◽  
Backward Chaining ◽  
Forward Chaining ◽  
Knowledge Based ◽  
Specific Symptoms

A doctor or medical scholar needs a reference book to learn how to diagnose tropical diseases. This reference book is sometimes a hassle if you have to carry it everywhere. This reference book is also impractical if you have to search it first to find the symptoms and diseases you want to study. So that we need a system to make it easier for doctors and medical scholars to study the science of diagnosis and look for symptoms and diseases. Expert systems are knowledge-based programs that provide expert quality solutions to problems in a specific domain. This expert system is used in the fields of medicine, agriculture, business, and others. Expert systems in the field of medicine make it easy to identify diseases suffered by patients through the symptoms present in the patient. This expert system helps doctors make diagnoses to convince doctors about the results of the diagnosis. The expert system in this study uses a combined method. The combined method is forward chaining and backward chaining. The forward chaining method is used to determine specific symptoms that appear, while the backward chaining method is used to trace general symptoms that arise from specific symptoms that have been previously selected. The result of combining these methods provides a diagnostic percentage of 100%. Meanwhile, the user's assessment of the system gives a good response.

scholarly journals Pilot Study on Exhaled Breath Analysis for a Healthy Adult Population in Hawaii

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3726
Author(s):  
Hunter R. Yamanaka ◽  
Cynthia Cheung ◽  
Jireh S. Mendoza ◽  
Danson J. Oliva ◽  
Kealina Elzey-Aberilla ◽  
...  
Keyword(s):  
Pilot Study ◽  
Prolonged Exposure ◽  
Healthy Adult ◽  
Adult Population ◽  
Acid Methyl Ester ◽  
Breath Analysis ◽  
Disease Diagnosis ◽  
Exhaled Breath ◽  
Testing Procedures ◽  
Range Finding

Fast diagnostic results using breath analysis are an anticipated possibility for disease diagnosis or general health screenings. Tests that do not require sending specimens to medical laboratories possess capabilities to speed patient diagnosis and protect both patient and healthcare staff from unnecessary prolonged exposure. The objective of this work was to develop testing procedures on an initial healthy subject cohort in Hawaii to act as a range-finding pilot study for characterizing the baseline of exhaled breath prior to further research. Using comprehensive two-dimensional gas chromatography (GC×GC), this study analyzed exhaled breath from a healthy adult population in Hawaii to profile the range of different volatile organic compounds (VOCs) and survey Hawaii-specific differences. The most consistently reported compounds in the breath profile of individuals were acetic acid, dimethoxymethane, benzoic acid methyl ester, and n-hexane. In comparison to other breathprinting studies, the list of compounds discovered was representative of control cohorts. This must be considered when implementing proposed breath diagnostics in new locations with increased interpersonal variation due to diversity. Further studies on larger numbers of subjects over longer periods of time will provide additional foundational data on baseline breath VOC profiles of control populations for comparison to disease-positive cohorts.

scholarly journals Knowledge Base Design for Diagnosis Pregnancy Problems

2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Farah Rifdah Arzumni ◽  
Rina Dewi Indahsari
Keyword(s):  
Expert System ◽  
Pregnant Women ◽  
Disease Diagnosis ◽  
Test Results ◽  
Backward Chaining ◽  
Decision Factors ◽  
System Diagnosis ◽  
Performance System ◽  
System Requirements ◽  
Specific Symptoms

In Indonesia, the death rate of pregnant women was still very high. Lack of knowledge about the perceived symptoms during pregnancy make pregnant women regardless of the specific symptoms that can be harmful and disease records indicate the causes of indirect maternal death in pregnant.  Moreover, the risk of pregnant mother mortality is also higher due to the delay in taking the decision factors for referenced. Based on the fact, the proposed solution in the form of expert system diagnosis of diseases of pregnant women using the method of Backward Chaining that can help recognize diseases during pregnancy to take place based on the perceived symptoms of pregnant women as well as references that should be targeted by the patient. The methods of the Backward Chaining have a performance system that is capable of running the functional needs and high accuracy percentage results. With the existence of a system of experts on pregnancy problems that use the Backward Chaining method can describe the level of confidence of an expert on the problem at hand. Based on the test results, obtained results 100% functionality of disease diagnosis expert system of pregnant women worked in accordance with a list of system requirements and the system.

Use of TEM in Plant Disease Diagnosis: A Xylem-Limited Bacterium Associated with Diseased ‘Toronto’ Creeping Bentgrass

1981 ◽  
Vol 39 ◽  
pp. 414-415
Author(s):  
Karen K. Baker ◽  
David L. Roberts
Keyword(s):  
Osmium Tetroxide ◽  
Plant Disease ◽  
Leaf Tissue ◽  
Infectious Agent ◽  
Creeping Bentgrass ◽  
Disease Diagnosis ◽  
Unknown Etiology ◽  
Agrostis Palustris ◽  
Putting Greens ◽  
Plant Disease Diagnosis

Plant disease diagnosis is most often accomplished by examination of symptoms and observation or isolation of causal organisms. Occasionally, diseases of unknown etiology occur and are difficult or impossible to accurately diagnose by the usual means. In 1980, such a disease was observed on Agrostis palustris Huds. c.v. Toronto (creeping bentgrass) putting greens at the Butler National Golf Course in Oak Brook, IL.The wilting symptoms of the disease and the irregular nature of its spread through affected areas suggested that an infectious agent was involved. However, normal isolation procedures did not yield any organism known to infect turf grass. TEM was employed in order to aid in the possible diagnosis of the disease.Crown, root and leaf tissue of both infected and symptomless plants were fixed in cold 5% glutaraldehyde in 0.1 M phosphate buffer, post-fixed in buffered 1% osmium tetroxide, dehydrated in ethanol and embedded in a 1:1 mixture of Spurrs and epon-araldite epoxy resins.

Perceptual Characteristics of Consonant Production in Apraxia of Speech and Aphasia

2019 ◽  
Vol 28 (4) ◽  
pp. 1411-1431 ◽  
Author(s):  
Lauren Bislick ◽  
William D. Hula
Keyword(s):  
Error Rate ◽  
Error Rates ◽  
Group Differences ◽  
Diagnostic Process ◽  
Apraxia Of Speech ◽  
Contextual Variables ◽  
Error Type ◽  
Type Distribution ◽  
Phonetic Features ◽  
Syllable Position

Purpose This retrospective analysis examined group differences in error rate across 4 contextual variables (clusters vs. singletons, syllable position, number of syllables, and articulatory phonetic features) in adults with apraxia of speech (AOS) and adults with aphasia only. Group differences in the distribution of error type across contextual variables were also examined. Method Ten individuals with acquired AOS and aphasia and 11 individuals with aphasia participated in this study. In the context of a 2-group experimental design, the influence of 4 contextual variables on error rate and error type distribution was examined via repetition of 29 multisyllabic words. Error rates were analyzed using Bayesian methods, whereas distribution of error type was examined via descriptive statistics. Results There were 4 findings of robust differences between the 2 groups. These differences were found for syllable position, number of syllables, manner of articulation, and voicing. Group differences were less robust for clusters versus singletons and place of articulation. Results of error type distribution show a high proportion of distortion and substitution errors in speakers with AOS and a high proportion of substitution and omission errors in speakers with aphasia. Conclusion Findings add to the continued effort to improve the understanding and assessment of AOS and aphasia. Several contextual variables more consistently influenced breakdown in participants with AOS compared to participants with aphasia and should be considered during the diagnostic process. Supplemental Material https://doi.org/10.23641/asha.9701690

Interleukin 10-induced thrombocytopenia in normal healthy adult volunteers: evidence for decreased platelet production

2000 ◽  
Vol 111 (1) ◽  
pp. 104-111 ◽  
Author(s):  
Jeffrey A. Sosman ◽  
Amit Verma ◽  
Steven Moss ◽  
Patricia Sorokin ◽  
Michael Blend ◽  
...  
Keyword(s):  
Healthy Adult ◽  
Interleukin 10 ◽  
Platelet Production ◽  
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