scholarly journals Biology, cultivation, and medicinal functions of the mushroom Hericium erinaceum

2016 ◽  
Vol 50 (2) ◽  
Author(s):  
Sławomir Sokół ◽  
Iwona Golak-Siwulska ◽  
Krzysztof Sobieralski ◽  
Marek Siwulski ◽  
Katarzyna Górka
Keyword(s):  
Cognitive Abilities ◽  
Case Reports ◽  
Natural Habitats ◽  
Bioactive Substances ◽  
Edible Fungus ◽  
Parkinson’S Diseases ◽  
Health Promoting ◽  
Hericium Erinaceum

<em>Hericium erinaceum</em> (Bull.: Fr.) Pers. is an edible fungus of great significance in medicine. It is rarely found in Europe, in contrast, it is common in Japan and North America. Its fruitbodies have been well-known for hundreds of years in traditional Chinese medicine and cuisine. A cradle of <em>H. erinaceum</em> cultivation is Asia. In Eastern Europe is rare in natural habitats, but can be successfully cultivated. Both fruitbodies and mycelia are rich in active, health promoting substances. Tests of substances extracted from this mushroom carried out on animals and in vitro have given good results. They can be used in the treatment of cancer, hepatic disorders, Alzheimer’s and Parkinson’s diseases, wound healing. They improve cognitive abilities, support the nervous and immune systems. Promising results have been reported in clinical trials and case reports about the human treatment (e.g., recovery from schizophrenia, an improvement of the quality of sleep, alleviation of the menopause symptoms). The subject of this paper is to summarize information about the development of mycelium, the best conditions for cultivation of fruitbodies, bioactive substances and their use in medicine.

scholarly journals Quality of New Functional Powdered Beverages Enriched with Lyophilized Fruits—Potentially Bioaccessible Antioxidant Properties, Nutritional Value, and Consumer Analysis

2020 ◽  
Vol 10 (11) ◽  
pp. 3668 ◽  
Author(s):  
Justyna Bochnak-Niedźwiecka ◽  
Michał Świeca
Keyword(s):  
Antioxidant Capacity ◽  
Raw Materials ◽  
Antioxidant Properties ◽  
Reducing Power ◽  
In Vitro Digestion ◽  
In Vitro Bioaccessibility ◽  
Trolox Equivalent ◽  
Health Promoting

This study evaluates nutrients and health-promoting compounds responsible for antioxidant capacity in eight novel formulations based on lyophilized fruit and vegetable powders. The composition contained lyophilized carrot, pumpkin, lentil sprouts, raspberry, strawberry, and apple. The effect of functional additives on the antioxidant, nutritional, and functional characteristics of powdered beverages was determined in the powders and after rehydration followed by in vitro digestion. The antioxidant activity, phenols, vitamin C, and reducing power were significantly higher in the powders enriched with additives having potential functional properties. Furthermore, the analyses indicated that all the powdered formulations may be potential sources of total starch (100–112 mg/100 mL) and proteins (125–139 mg/100 mL). The designed powdered beverages after reconstitution exhibited high antioxidant content, reasonable consumer acceptance, and good in vitro bioaccessibility. The best results of antioxidant capacity were obtained for beverages enriched with raspberry, i.e., 10.4 mg Trolox equivalent (TE)/100 mL and 12.1 mg TE/100 mL rehydrated at 20 °C and 80 °C, respectively. Additionally, color characteristics were used as indicators of the quality of the powdered beverages. This research promotes the reduction of food waste, since whole plant tissues are used, thus allowing maximum exploitation of food raw materials; moreover, drying provides stable shelf life.

scholarly journals BioaccessibilityIn Vitroof Nutraceuticals from Bark of SelectedSalixSpecies

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Urszula Gawlik-Dziki ◽  
Danuta Sugier ◽  
Dariusz Dziki ◽  
Piotr Sugier
Keyword(s):  
Phenolic Acids ◽  
Sandy Soil ◽  
Genetic Factors ◽  
Antiradical Activity ◽  
Extraction System ◽  
Natural Habitats ◽  
Reducing Ability ◽  
Health Promoting ◽  
Extractable Compounds

The aim of this study was to investigate and to compare the extractability, bioaccessibility, and bioavailabilityin vitroof antioxidative compounds from bark of selectedSalixspecies:S. alba (SA), S. daphnoides (SD), S. purpurea (SP),andS. daphnoides x purpurea (SDP)hybrid willow clones originating from their natural habitats and cultivated on the sandy soil. The highest amount of phenolic glycosides was found in the bark ofSDPandSD. The best source of phenolics was bark ofSDP. The highest content of flavonoids were found inSDbark samples, whereas the highest concentration of bioaccessible and bioavailable phenolic acids was determined inSDPbark. Bark of all testedSalixspecies showed significant antiradical activity. This properties are strongly dependent on extraction system and genetic factors. Regardless ofSalixgenotypes, the lowest chelating power was found for chemically-extractable compounds. Bark of allSalixspecies contained ethanol-extractable compounds with reducing ability. Besides this, high bioaccessibility and bioavailabilityin vitroofSalixbark phytochemicals were found. Obtained results indicate that extracts from bark testedSalixgenotypes can provide health promoting benefits to the consumers; however, this problem requires further study.

scholarly journals Bioactive Phenolic Compounds from Primula veris L.: Influence of the Extraction Conditions and Purification

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 997
Author(s):  
Maria Tarapatskyy ◽  
Aleksandra Gumienna ◽  
Patrycja Sowa ◽  
Ireneusz Kapusta ◽  
Czesław Puchalski
Keyword(s):  
Selective Extraction ◽  
Bioactive Substances ◽  
Plant Extraction ◽  
Primula Veris ◽  
Health Promoting ◽  
Phase Liquid ◽  
Efficient Extraction ◽  
Ethanol Extracts ◽  
The Individual

Our experiments may help to answer the question of whether cowslip (Primula veris L.) is a rich source of bioactive substances that can be obtained by efficient extraction with potential use as a food additive. A hypothesis assumed that the type of solvent used for plant extraction and the individual morphological parts of Primula veris L. used for the preparation of herbal extracts will have key impacts on the efficiency of the extraction of bioactive compounds, and thus, the health-promoting quality of plant concentrates produced. Most analysis of such polyphenolic compound contents in extracts from Primula veris L. has been performed by using chromatography methods such as ultra-performance reverse-phase liquid chromatography (UPLC−PDA−MS/MS). Experiments demonstrated that the most effective extraction agent for fresh study material was water at 100 °C, whereas for dried material it was 70% ethanol. The richest sources of polyphenolic compounds were found in cowslip primrose flowers and leaves. The aqueous and ethanol extracts from Primula veris L. were characterized by a quantitatively rich profile of polyphenolic substances, and a high antioxidative potential. Selective extraction with the use of mild conditions and neutral solvents is the first step to obtaining preparations from cowslip primrose with a high content of bioactive substances.

scholarly journals Viburnum opulus L.—A Review of Phytochemistry and Biological Effects

Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3398
Author(s):  
Dominika Kajszczak ◽  
Małgorzata Zakłos-Szyda ◽  
Anna Podsędek
Keyword(s):  
Biological Effects ◽  
In Vivo Studies ◽  
Chemical Compositions ◽  
Viburnum Opulus ◽  
Natural Habitats ◽  
Gram Positive Bacteria ◽  
North Asia ◽  
Health Promoting

Viburnum opulus (VO) is a valuable decorative, medicinal, and food plant. This deciduous shrub is found in natural habitats in Europe, Russia, and some regions in North Africa and North Asia. The VO is traditionally used to treat aliments such as cough, colds, tuberculosis, rheumatic aches, ulcers, stomach, and kidney problems, among others. Many of the health-promoting properties of VO are associated with antioxidant activity, which has been demonstrated in both in vitro and in vivo studies. The results of in vitro studies show the antimicrobial potential of VO, especially against Gram-positive bacteria. In cell-based studies, VO demonstrated anti-inflammatory, anti-obesity, anti-diabetic, osteogenic, cardio-protective, and cytoprotective properties. The applicability of VO in the treatment of urinary tract diseases, endometriosis, and some cancers has been confirmed in in vivo studies. The health benefits of VO result from the presence of bioactive components such as phenolic compounds, vitamin C, carotenoids, iridoids, and essential oils. The aim of this review is to present an overview of the botanical characteristics, chemical compositions, including bioactive compounds, and pro-health properties of VO different morphological parts.

scholarly journals MEDICINAL PROPERTIES OF HERICIUM ERINACEUS

2021 ◽  
Vol 6 (10(60)) ◽  
pp. 3-8
Author(s):  
Bulat Musulmanbekovich Aikeshev ◽  
Ayaulym Arystanbay
Keyword(s):  
Cognitive Abilities ◽  
Edible Mushroom ◽  
Biologically Active ◽  
Medicinal Mushrooms ◽  
Hericium Erinaceus ◽  
Parkinson’S Diseases ◽  
History Of ◽  
Medicinal Properties ◽  
History Of Use

Medicinal mushrooms have become an attractive topic due to their bioactive compounds potentially useful for therapeutic use. Among the growing popularity of medicinal mushrooms is Hericium erinaceus. Hericium erinaceus is a medicinal edible mushroom with a long history of use in traditional Chinese medicine as well as in other countries of the East. Along with this, several of its biologically active compounds served as the basis for the creation of nutritional supplements. Its fruiting bodies and mycelium are rich in active substances that promote health. Tests of substances extracted from this fungus in animals and in vitro have given good results. They are beginning to be used in the treatment of cancer, liver diseases, Alzheimer’s and Parkinson’s diseases, and wound healing. They improve cognitive abilities, support the nervous and immune systems.

Bioactive Peptides Sensitize Cells to Anticancer Effects of Oxaliplatin in Human Colorectal Cancer Xenografts in Nude Mice

2019 ◽  
Vol 26 (7) ◽  
pp. 512-522
Author(s):  
Xian Li ◽  
Long Xia ◽  
Xiaohui Ouyang ◽  
Qimuge Suyila ◽  
Liya Su ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Nude Mice ◽  
Low Dose ◽  
Bioactive Peptides ◽  
Human Colorectal Cancer ◽  
Short Term ◽  
Hct 116

<P>Background: Despite new agent development and short-term benefits in patients with Colorectal Cancer (CRC), metastatic CRC cure rates have not improved due to high rates of oxaliplatin resistance and toxicity. There is an urgent need for effective tools to prevent and treat CRC and reduce morbidity and mortality of CRC patients. Exploring the effects of bioactive peptides on the antitumor to CRC was of vital importance to the clinical application. </P><P> Objective: This study aimed to investigate the therapeutic impact of Anticancer Bioactive Peptides (ACBP) on anticancer effect of oxaliplatin (LOHP) in human colorectal cancer xenografts models in nude mice. </P><P> Methods: HCT-116 cells were cultured in vitro via CCK-8 assays and the absorbance was measured at 450 nm. Apoptosis and cell cycle were assessed by Flow Cytometry (FCM) in vitro. HCT-116 human colorectal cancer cells inoculated subcutaneously in nude mice of treatment with PBS (GG), ACBP, LOHP, ACBP+LOHP (A+L) in vivo. The quality of life was assessed by dietary amount of nude mice, the weight of nude mice, inhibition rates, tumor weight and tumor volume. Immunohistochemistry and RT-qPCR method was conducted to determine the levels of apoptosisregulating proteins/genes in transplanted tumors. </P><P> Results: ACBP induced substantial reductions in viable cell numbers and apoptosis of HCT116 cells in combined with LOHP in vitro. Compared with the control GG group, ACBP combined low dose oxaliplatin (U) group demonstrated significantly different tumor volume, the rate of apoptosis, the expression levels of Cyt-C, caspase-3,8,9 proteins and corresponding RNAs (P<0.05). The expression of pro-apoptotic proteins in the cytoplasm around the nucleus was significantly enhanced by ACBP. Short term intermittent use of ACBP alone indicted a certain inhibitory effect on tumor growth, and improve the quality of life of tumor bearing nude mice. </P><P> Conclusion: ACBP significantly increased the anti-cancer responses of low dose oxaliplatin (L-LOHP), thus, significantly improving the quality of life of tumor-bearing nude mice.</P>

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