scholarly journals Association between maternal diabetes mellitus and the risk of congenital malformations: A meta-analysis of cohort studies

2015 ◽  
Vol 9 (4) ◽  
pp. 274-281 ◽  
Author(s):  
Enfa Zhao ◽  
Yafei Zhang ◽  
Xianling Zeng ◽  
Baomin Liu
Keyword(s):  
Diabetes Mellitus ◽  
Cohort Studies ◽  
Congenital Malformations ◽  
Meta Analysis ◽  
Maternal Diabetes ◽  
Maternal Diabetes Mellitus

Hydrops Fetalis and Congenital Syphilis

PEDIATRICS ◽  
1972 ◽  
Vol 49 (2) ◽  
pp. 285-287
Author(s):  
Stephen I. Bulova ◽  
Elias Schwartz ◽  
William V. Harrer
Keyword(s):  
Diabetes Mellitus ◽  
Congenital Malformations ◽  
Congenital Syphilis ◽  
Maternal Diabetes ◽  
Hydrops Fetalis ◽  
Red Cell ◽  
Alpha Thalassemia ◽  
Fetal Malformations ◽  
Congenital Nephrosis ◽  
Maternal Diabetes Mellitus

Hydrops fetalis is associated most commonly with erythroblastosis fetalis due to fetal-maternal incompatibility of the red cell Rh antigens. Many nonimmunologic disorders, including infections, homozygous alpha thalassemia, maternal diabetes mellitus, fetal malformations, the twin transfusion syndrome, and congenital nephrosis, may cause a similar syndrome. Although congenital syphilis has been mentioned as a cause of hydrops fetalis, reports of the association antedate the use of immunologic methods capable of detecting isoimmunization. We report here an hydropic infant with syphilis in whom there was no evidence of Coombs-positive hemolytic anemia, alpha thalassemia, or severe congenital malformations. See table in the PDF file See image in the PDF file

Congenital Heart Disease and Maternal Diabetes Mellitus

2018 ◽  
Vol 1 (4) ◽  
pp. 32-39
Author(s):  
Nabil Z Seyidov ◽  
Andreas Petropoulos ◽  
A Khudiyeva ◽  
İ İsmailova
Keyword(s):  
Diabetes Mellitus ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Malformations ◽  
Congenital Heart ◽  
Early Stage ◽  
Maternal Diabetes ◽  
Healthy Population ◽  
Maternal Diabetes Mellitus ◽  
Diabetic Mothers

Diabetes mellitus is a relatively common illness that can complicate pregnancy and result in an increased incidence of congenital malformations. Offspring of diabetic mothers suffering from type IDDM have a fivefold incidence of congenital malformations compared to pregnancies in the general healthy population. Specifically, the pattern of congenital heart disease (CHD) encountered among this group, with an emphasis on abnormalities of laterality, looping and conotruncal septation, suggesting that the maternal metabolic state affects cardiogenesis at a very early stage of the developmental period, prior to 7 weeks of gestation. Although many have been written on the effect of diabetes in pregnant women, less is known for the effects of type II DM and gestational diabetes mellitus (GDM) and its role in provoking CHD. Aim of this paper is to review the literature regarding the types of CHD seen in offspring of mothers suffering from different types of diabetes mellitus, maternal types 1 and 2 and gestational and to comment on the incidences and any differences found in the types of detected CHD.

Congenital Heart Disease and Maternal Diabetes Mellitus

2018 ◽  
Vol 1 (3) ◽  
pp. 32-39
Author(s):  
Andreas Petropoulos ◽  
A Khudiyeva ◽  
İ İsmailova
Keyword(s):  
Diabetes Mellitus ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Malformations ◽  
Congenital Heart ◽  
Early Stage ◽  
Maternal Diabetes ◽  
Healthy Population ◽  
Maternal Diabetes Mellitus ◽  
Diabetic Mothers

Diabetes mellitus is a relatively common illness that can complicate pregnancy and result in an increased incidence of congenital malformations. Offspring of diabetic mothers suffering from type IDDM have a fivefold incidence of congenital malformations compared to pregnancies in the general healthy population. Specifically, the pattern of congenital heart disease (CHD) encountered among this group, with an emphasis on abnormalities of laterality, looping and conotruncal septation, suggesting that the maternal metabolic state affects cardiogenesis at a very early stage of the developmental period, prior to 7 weeks of gestation. Although many have been written on the effect of diabetes in pregnant women, less is known for the effects of type II DM and gestational diabetes mellitus (GDM) and its role in provoking CHD. Aim of this paper is to review the literature regarding the types of CHD seen in offspring of mothers suffering from different types of diabetes mellitus, maternal types 1 and 2 and gestational and to comment on the incidences and any differences found in the types of detected CHD.

scholarly journals Non-autoimmune diabetes mellitus and the risk of virus infections: a systematic review and meta-analysis of case-control and cohort studies

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Eric Lontchi-Yimagou ◽  
Charly Feutseu ◽  
Sebastien Kenmoe ◽  
Alexandra Lindsey Djomkam Zune ◽  
Solange Fai Kinyuy Ekali ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Cohort Studies ◽  
H1n1 Virus ◽  
Autoimmune Diabetes ◽  
Meta Analysis ◽  
Case Control ◽  
Cochrane Central Register ◽  
Virus Infections ◽  
Autoimmune Diabetes Mellitus

AbstractA significant number of studies invoked diabetes as a risk factor for virus infections, but the issue remains controversial. We aimed to examine whether non-autoimmune diabetes mellitus enhances the risk of virus infections compared with the risk in healthy individuals without non-autoimmune diabetes mellitus. In this systematic review and meta-analysis, we assessed case-control and cohort studies on the association between non-autoimmune diabetes and viruses. We searched PubMed, Embase, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, and Web of Science with no language restriction, to identify articles published until February 15, 2021. The main outcome assessment was the risk of virus infection in individuals with non-autoimmune diabetes. We used a random-effects model to pool individual studies and assessed heterogeneity (I2) using the χ2 test on Cochrane’s Q statistic. This study is registered with PROSPERO, number CRD42019134142. Out of 3136 articles identified, we included 68 articles (90 studies, as the number of virus and or diabetes phenotype varied between included articles). The summary OR between non-autoimmune diabetes and virus infections risk were, 10.8(95% CI: 10.3–11.4; 1-study) for SARS-CoV-2; 3.6(95%CI: 2.7–4.9, I2 = 91.7%; 43-studies) for HCV; 2.7(95% CI: 1.3–5.4, I2 = 89.9%, 8-studies;) for HHV8; 2.1(95% CI: 1.7–2.5; 1-study) for H1N1 virus; 1.6(95% CI: 1.2–2.13, I2 = 98.3%, 27-studies) for HBV; 1.5(95% CI: 1.1–2.0; 1-study) for HSV1; 3.5(95% CI: 0.6–18.3 , I2 = 83.9%, 5-studies) for CMV; 2.9(95% CI: 1–8.7, 1-study) for TTV; 2.6(95% CI: 0.7–9.1, 1-study) for Parvovirus B19; 0.7(95% CI: 0.3–1.5 , 1-study) for coxsackie B virus; and 0.2(95% CI: 0–6.2; 1-study) for HGV. Our findings suggest that, non-autoimmune diabetes is associated with increased susceptibility to viruses especially SARS-CoV-2, HCV, HHV8, H1N1 virus, HBV and HSV1. Thus, these viruses deserve more attention from diabetes health-care providers, researchers, policy makers, and stakeholders for improved detection, overall proper management, and efficient control of viruses in people with non-autoimmune diabetes.

scholarly journals 288 Assessing in vivo placental function in pregnancies complicated by maternal diabetes mellitus

2021 ◽  
Vol 224 (2) ◽  
pp. S188-S189
Author(s):  
Stacey Gold ◽  
Catherine Lopez ◽  
Jessica L. Quistorff ◽  
Sarah Downs ◽  
Sara Iqbal ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Maternal Diabetes ◽  
Placental Function ◽  
Maternal Diabetes Mellitus
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