The Evaluation Of The Role Of Hyperbaric Oxygen Therapy In Preventing The Ischemia-Reperfusion Injury Following Experimental Testicular Torsion

10.5580/f5a ◽  
2005 ◽  
Vol 2 (2) ◽  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Testicular Torsion ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion

scholarly journals Effect of hyperbaric oxygen therapy on the intestinal ischemia reperfusion injury

2011 ◽  
Vol 26 (6) ◽  
pp. 463-469 ◽  
Author(s):  
Rosemary Aparecida Furlan Daniel ◽  
Vinícius Kannen Cardoso ◽  
Emanuel Góis Jr ◽  
Rogério Serafim Parra ◽  
Sérgio Britto Garcia ◽  
...  
Keyword(s):  
Cell Viability ◽  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Intestinal Ischemia ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Exact Nature ◽  
Intestinal Tissue

PURPOSE: Adequate tissue oxygenation is essential for healing. Hyperbaric oxygen therapy (HBOT) has potential clinical applications to treat ischemic pathologies, however the exact nature of any protective effects are unclear at present. We therefore investigated the potential role of HBOT in modulating the ischemia/reperfusion (I/R) injury response in intestinal model of I/R injury. METHODS: Male Wistar rats were subjected to surgery for the induction of intestinal ischemia followed by reperfusion. HBOT was provided before and/or after intestinal ischemia. Cell viability in the intestinal tissue was assessed using the MTT assay and by measuring serum malondealdehyde (MDA). Microvascular density and apoptosis were evaluated by immunohistochemistry. RESULTS: The results indicate that HBOT treatment pre- and post-ischemia reduces lesion size to the intestinal tissue. This treatment increases cell viability and reduces the activation of caspase-3, which is associated with increased number of tissue CD34 cells and enhanced VEGF expression. CONCLUSION: The hyperbaric oxygen therapy can limit tissue damage due to ischemia/reperfusion injury, by inducing reparative signaling pathways.

Effects of hyperbaric oxygen therapy on the rat intestinal mucosa apoptosis caused by ischemia-reperfusion injury

Microsurgery ◽  
2007 ◽  
Vol 27 (4) ◽  
pp. 224-227 ◽  
Author(s):  
Paulo Roberto Bertoletto ◽  
Djalma José Fagundes ◽  
Manuel De Jesus Simões ◽  
Celina T.F. Oshima ◽  
Edna Frasson De Souza Montero ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Intestinal Mucosa ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion

EFFECT OF HYPERBARIC OXYGEN THERAPY ON TESTICULAR ISCHEMIA-REPERFUSION INJURY

1998 ◽  
pp. 601-604
Author(s):  
JOHM M. KOLSKI ◽  
PETER J. MAZOLEWSKI ◽  
LINDA L. STEPHENSON ◽  
JOHN TEXTER ◽  
VICTOR E. GRIGORIEV ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Testicular Ischemia

EFFECT OF HYPERBARIC OXYGEN THERAPY ON TESTICULAR ISCHEMIA-REPERFUSION INJURY

1998 ◽  
Vol 160 (2) ◽  
pp. 601-604 ◽  
Author(s):  
JOHM M. KOLSKI ◽  
PETER J. MAZOLEWSKI ◽  
LINDA L. STEPHENSON ◽  
JOHN TEXTER ◽  
VICTOR E. GRIGORIEV ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Testicular Ischemia

Hyperbaric Oxygen Therapy Attenuates Renal Ischemia/Reperfusion Injury in Rats

2007 ◽  
Vol 78 (1) ◽  
pp. 82-85 ◽  
Author(s):  
Emrullah Solmazgul ◽  
Gunalp Uzun ◽  
Hakan Cermik ◽  
Enes M. Atasoyu ◽  
Secil Aydinoz ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Renal Ischemia ◽  
Renal Ischemia Reperfusion Injury

scholarly journals Effects of hyperbaric oxygen therapy as hepatic preconditioning in rats submitted to hepatic ischemia/reperfusion injury

2014 ◽  
Vol 29 (suppl 2) ◽  
pp. 61-66 ◽  
Author(s):  
Daniele Moraes Losada ◽  
Agnaldo Bruno Chies ◽  
Omar Feres ◽  
Eleazar Chaib ◽  
Luiz Augusto Carneiro D'Albuquerque ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Hepatic Ischemia ◽  
Hepatic Ischemia Reperfusion

scholarly journals Hyperbaric oxygen therapy aggravates liver reperfusion injury in rats

2008 ◽  
Vol 23 (4) ◽  
pp. 315-321 ◽  
Author(s):  
Cristiano Xavier Lima ◽  
Marcelo Dias Sanches ◽  
João Baptista de Rezende Neto ◽  
Roberto Carlos de Oliveira e Silva ◽  
Mauro Martins Teixeira ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Ambient Air ◽  
Myeloperoxidase Activity ◽  
Ischemia And Reperfusion ◽  
Liver Ischemia

PURPOSE: To evaluate the effects of hyperbaric oxygen (HO) therapy in the protection against liver ischemia/reperfusion injury. METHODS: Thirty-two male Wistar rats were divided into four groups of eight animals each: group A - laparotomy and liver manipulation, group B - liver ischemia and reperfusion, group C - HO pretreatment for 60 min followed by liver ischemia and reperfusion, and group D - pretreatment with ambient air at 2.5 absolute atmospheres for 60 min followed by liver ischemia and reperfusion. Plasma was assayed for aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LDH). Intra-arterial blood pressure was monitored continuously. Myeloperoxidase activity in the liver and lung was assessed 30 min after reperfusion. RESULTS: Plasma AST, ALT and LDH increased after reperfusion in all animals. Plasma ALT values and myeloperoxidase activity in the liver parenchyma were higher in HO-pretreated animals than in groups A, B and D. HO had a negative hemodynamic effect during liver reperfusion. CONCLUSION: Liver preconditioning with hyperbaric oxygen therapy aggravated liver ischemia/reperfusion injury in rats as demonstrated by plasma ALT and liver myeloperoxidase activity.

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