Hyperbaric Oxygen Therapy Attenuates Renal Ischemia/Reperfusion Injury in Rats

2007 ◽  
Vol 78 (1) ◽  
pp. 82-85 ◽  
Author(s):  
Emrullah Solmazgul ◽  
Gunalp Uzun ◽  
Hakan Cermik ◽  
Enes M. Atasoyu ◽  
Secil Aydinoz ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Renal Ischemia ◽  
Renal Ischemia Reperfusion Injury

scholarly journals Effect of hyperbaric oxygen therapy on the intestinal ischemia reperfusion injury

2011 ◽  
Vol 26 (6) ◽  
pp. 463-469 ◽  
Author(s):  
Rosemary Aparecida Furlan Daniel ◽  
Vinícius Kannen Cardoso ◽  
Emanuel Góis Jr ◽  
Rogério Serafim Parra ◽  
Sérgio Britto Garcia ◽  
...  
Keyword(s):  
Cell Viability ◽  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Intestinal Ischemia ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Exact Nature ◽  
Intestinal Tissue

PURPOSE: Adequate tissue oxygenation is essential for healing. Hyperbaric oxygen therapy (HBOT) has potential clinical applications to treat ischemic pathologies, however the exact nature of any protective effects are unclear at present. We therefore investigated the potential role of HBOT in modulating the ischemia/reperfusion (I/R) injury response in intestinal model of I/R injury. METHODS: Male Wistar rats were subjected to surgery for the induction of intestinal ischemia followed by reperfusion. HBOT was provided before and/or after intestinal ischemia. Cell viability in the intestinal tissue was assessed using the MTT assay and by measuring serum malondealdehyde (MDA). Microvascular density and apoptosis were evaluated by immunohistochemistry. RESULTS: The results indicate that HBOT treatment pre- and post-ischemia reduces lesion size to the intestinal tissue. This treatment increases cell viability and reduces the activation of caspase-3, which is associated with increased number of tissue CD34 cells and enhanced VEGF expression. CONCLUSION: The hyperbaric oxygen therapy can limit tissue damage due to ischemia/reperfusion injury, by inducing reparative signaling pathways.

Effects of hyperbaric oxygen therapy on the rat intestinal mucosa apoptosis caused by ischemia-reperfusion injury

Microsurgery ◽  
2007 ◽  
Vol 27 (4) ◽  
pp. 224-227 ◽  
Author(s):  
Paulo Roberto Bertoletto ◽  
Djalma José Fagundes ◽  
Manuel De Jesus Simões ◽  
Celina T.F. Oshima ◽  
Edna Frasson De Souza Montero ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Intestinal Mucosa ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion

EFFECT OF HYPERBARIC OXYGEN THERAPY ON TESTICULAR ISCHEMIA-REPERFUSION INJURY

1998 ◽  
pp. 601-604
Author(s):  
JOHM M. KOLSKI ◽  
PETER J. MAZOLEWSKI ◽  
LINDA L. STEPHENSON ◽  
JOHN TEXTER ◽  
VICTOR E. GRIGORIEV ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Testicular Ischemia
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