Role of Eosinophil Cationic Protein in Asthma and Confounding Factors.

10.5580/e4c ◽  
2010 ◽  
Vol 7 (2) ◽  
Keyword(s):  
Eosinophil Cationic Protein ◽  
Confounding Factors ◽  
Cationic Protein

The role of eosinophils and eosinophil cationic protein in oral cancer: A review

2011 ◽  
Vol 56 (4) ◽  
pp. 353-358 ◽  
Author(s):  
Michele Conceição Pereira ◽  
Denise Tostes Oliveira ◽  
Luiz Paulo Kowalski
Keyword(s):  
Oral Cancer ◽  
Eosinophil Cationic Protein ◽  
Cationic Protein

scholarly journals The Role of Eosinophil Cationic Protein in Patients with Mycoplasma pneumoniae Infection

2008 ◽  
Vol 71 (1) ◽  
pp. 37-39 ◽  
Author(s):  
Chun-Jen Chen ◽  
Miao-Chiu Hung ◽  
Kai-Liang Kuo ◽  
Jui-Lung Chung ◽  
Keh-Gong Wu ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Eosinophil Cationic Protein ◽  
Cationic Protein ◽  
Mycoplasma Pneumoniae Infection

Eosinophil-induced neurotoxicity: The role of eosinophil cationic protein/RNase 3

2010 ◽  
Vol 227 (1-2) ◽  
pp. 60-70 ◽  
Author(s):  
Susanna Navarro ◽  
Ester Boix ◽  
Claudi M. Cuchillo ◽  
M. Victòria Nogués
Keyword(s):  
Eosinophil Cationic Protein ◽  
Cationic Protein

Dissecting the role of eosinophil cationic protein in upper airway disease

2012 ◽  
Vol 12 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Jonas Bystrom ◽  
Smita Y. Patel ◽  
Kawa Amin ◽  
David Bishop-Bailey
Keyword(s):  
Eosinophil Cationic Protein ◽  
Upper Airway ◽  
Airway Disease ◽  
Cationic Protein ◽  
Upper Airway Disease

Role of Serum Eosinophil Cationic Protein in the Monitoring of Children with Bronchial Asthma and Rhinitis

1998 ◽  
Vol 12 (2) ◽  
pp. 129-138 ◽  
Author(s):  
WEN-YI LEE ◽  
MEI-HUI YANG ◽  
LI-CHEN CHEN ◽  
SYH-JAE LIN ◽  
JING-LONG HUANG
Keyword(s):  
Bronchial Asthma ◽  
Eosinophil Cationic Protein ◽  
Cationic Protein

Mechanisms of Eosinophil Cationic Protein Release in the Serum: Role of Adhesion Molecules

1999 ◽  
Vol 120 (1) ◽  
pp. 60-64 ◽  
Author(s):  
Yoshiko Kato ◽  
Takao Fujisawa ◽  
Akihiko Terada ◽  
Kosei Iguchi ◽  
Hitoshi Kamiya
Keyword(s):  
Adhesion Molecules ◽  
Eosinophil Cationic Protein ◽  
Protein Release ◽  
Cationic Protein

scholarly journals Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

2017 ◽  
Vol 214 (7) ◽  
pp. 2121-2138 ◽  
Author(s):  
Stefan Uderhardt ◽  
Jochen A. Ackermann ◽  
Tobias Fillep ◽  
Victoria J. Hammond ◽  
Johann Willeit ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Large Scale ◽  
Eosinophil Cationic Protein ◽  
Regulatory Elements ◽  
Cationic Protein ◽  
Thrombotic Disease ◽  
Predictive Risk Factor ◽  
Intravascular Thrombosis ◽  
Predictive Risk

Blood coagulation is essential for physiological hemostasis but simultaneously contributes to thrombotic disease. However, molecular and cellular events controlling initiation and propagation of coagulation are still incompletely understood. In this study, we demonstrate an unexpected role of eosinophils during plasmatic coagulation, hemostasis, and thrombosis. Using a large-scale epidemiological approach, we identified eosinophil cationic protein as an independent and predictive risk factor for thrombotic events in humans. Concurrent experiments showed that eosinophils contributed to intravascular thrombosis by exhibiting a strong endogenous thrombin-generation capacity that relied on the enzymatic generation and active provision of a procoagulant phospholipid surface enriched in 12/15-lipoxygenase–derived hydroxyeicosatetraenoic acid–phosphatidylethanolamines. Our findings reveal a previously unrecognized role of eosinophils and enzymatic lipid oxidation as regulatory elements that facilitate both hemostasis and thrombosis in response to vascular injury, thus identifying promising new targets for the treatment of thrombotic disease.

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