Is Any Factor Influence On Hepatitis B Vaccination Response In Hemodialysis Patients?

10.5580/2649 ◽  
2006 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Hepatitis B ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccination ◽  
Vaccination Response

scholarly journals Hepatitis B Vaccination Response in Hemodialysis Patients: The Impact of Dialysis Shift

2021 ◽  
pp. 1-8
Author(s):  
Maggie Han ◽  
Xiaoling Ye ◽  
Sharon Rao ◽  
Schantel Williams ◽  
Stephan Thijssen ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Multivariate Regression ◽  
Clinical Laboratory ◽  
Seroconversion Rate ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccination ◽  
Start Time ◽  
Vaccination Response ◽  
Dialysis Vintage ◽  
The Impact

<b><i>Background/Aims:</i></b> Hepatitis B (HB) vaccination in hemodialysis patients is important as they are at a higher risk of contracting HB. However, hemodialysis patients have a lower HB seroconversion rate than their healthy counterparts. As better sleep has been associated with better seroconversion in healthy populations and early hemodialysis start has been linked to significant sleep-wake disturbances in hemodialysis patients, we examined if hemodialysis treatment start time is associated with HB vaccination response. <b><i>Methods:</i></b> Demographics, standard-of-care clinical, laboratory, and treatment parameters, dialysis shift data, HB antigen status, HB vaccination status, and HB titers were collected from hemodialysis patients in Fresenius clinics from January 2010 to December 2015. Patients in our analysis received 90% of dialysis treatments either before or after 8:30 a.m., were negative for HB antigen, and received a complete series of HB vaccination (Engerix B® or Recombivax HB™). Univariate and multivariate regression models examined whether dialysis start time is a predictor of HB vaccination response. <b><i>Results:</i></b> Patients were 65 years old, 57% male, and had a HD vintage of 10 months. Patients whose dialysis treatments started before 8:30 a.m. were more likely to be younger, male, and have a greater dialysis vintage. Patients receiving Engerix B® and starting dialysis before 8:30 a.m. had a significantly higher seroconversion rate compared to patients who started dialysis after 8:30 a.m. Early dialysis start was a significant predictor of seroconversion in univariate and multivariate regression including male gender, but not in multivariate regression including age, neutrophil-to-lymphocyte ratio, and vintage. <b><i>Conclusion:</i></b> While better sleep following vaccination is associated with seroconversion in the general population, this is not the case in hemodialysis patients after multivariate adjustment. In the context of end-stage kidney disease, early dialysis start is not a significant predictor of HB vaccination response. The association between objectively measured postvaccination sleep duration and seroconversion rate should be investigated.

Effect of Oral Levamisole Supplementation to Hepatitis B Vaccination on the Rate of Immune Response in Chronic Hemodialysis Patients

Nephron ◽  
2000 ◽  
Vol 84 (3) ◽  
pp. 291-292 ◽  
Author(s):  
M. Deniz Ayli ◽  
Cüneyt Ensari ◽  
Meltem Ayli ◽  
Fahri Mandiroglu ◽  
Suat Mut
Keyword(s):  
Immune Response ◽  
Hepatitis B ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Hepatitis B Vaccination

scholarly journals 77 Late results of hepatitis B vaccination in hemodialysis patients

2006 ◽  
Vol 10 ◽  
pp. S43
Author(s):  
M. Zubkin ◽  
E. Balakirev ◽  
V. Chervinko ◽  
F. Baranova ◽  
V. Taranov ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Late Results ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccination

Antibody Level after Hepatitis B Vaccination in Hemodialysis Patients: Influence of Hepatitis C Virus Infection

1996 ◽  
Vol 16 (2) ◽  
pp. 95-97 ◽  
Author(s):  
Juan F. Navarro ◽  
Jos&eacute; L. Teruel ◽  
Maria L. Mateos ◽  
Roberto Marcen ◽  
Joaqu&iacute;n Ortu&ntilde;o
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis B ◽  
Antibody Level ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccination ◽  
Hepatitis C Virus Infection
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