scholarly journals The Concept of Metabolic Syndrome: Contribution of Visceral Fat Accumulation and Its Molecular Mechanism

2011 ◽  
Vol 18 (8) ◽  
pp. 629-639 ◽  
Author(s):  
Yuji Matsuzawa ◽  
Tohru Funahashi ◽  
Tadashi Nakamura
Keyword(s):  
Metabolic Syndrome ◽  
Molecular Mechanism ◽  
Visceral Fat ◽  
Fat Accumulation ◽  
Visceral Fat Accumulation

scholarly journals Population Approaches Targeting Metabolic Syndrome Focusing on Japanese Trials

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1430 ◽  
Author(s):  
Hitoshi Nishizawa ◽  
Iichiro Shimomura
Keyword(s):  
Primary Care ◽  
Metabolic Syndrome ◽  
Visceral Fat ◽  
Behavioral Interventions ◽  
Lifestyle Modification ◽  
Task Force ◽  
Clinical Importance ◽  
Fat Accumulation ◽  
Screening Programs ◽  
Visceral Fat Accumulation

The clinical importance of assessment of metabolic syndrome lies in the selection of individuals with multiple risk factors based on visceral fat accumulation, and helping them to reduce visceral fat. Behavioral modification by population approach is important, which adds support to the personal approach. The complexity of visceral fat accumulation requires multicomponent and multilevel intervention. Preparation of food and physical environments could be useful strategies for city planners. Furthermore, actions on various frameworks, including organizational, community, and policy levels, have been recently reported. There are universal public health screening programs and post-screening health educational systems in Japan, and diseases management programs in Germany. Understanding one’s own health status is important for motivation for lifestyle modification. The U.S. Preventive Services Task Force recommends that primary care practitioners screen all adults for obesity and offer behavioral interventions and intensive counseling. Established evidence-based guidelines for behavioral counseling are needed within the primary care setting.

scholarly journals Bifidobacterium adolescentis supplementation ameliorates visceral fat accumulation and insulin sensitivity in an experimental model of the metabolic syndrome

2011 ◽  
Vol 107 (10) ◽  
pp. 1429-1434 ◽  
Author(s):  
Jinjin Chen ◽  
Ren Wang ◽  
Xiao-Fang Li ◽  
Rui-Liang Wang
Keyword(s):  
Metabolic Syndrome ◽  
Insulin Sensitivity ◽  
Visceral Fat ◽  
The Other ◽  
Standard Diet ◽  
Fat Pad ◽  
Bifidobacterium Adolescentis ◽  
Fat Accumulation ◽  
Visceral Fat Accumulation ◽  
The Metabolic Syndrome

The aim of the present study was to investigate the effects of Bifidobacterium adolescentis (Bif) supplementation on visceral fat accumulation and insulin sensitivity of the metabolic syndrome in HF-diet-fed rats. Adult male Wistar rats (n 10 per group) were fed four different experimental diets for 12 weeks as follows: standard diet; high-fat (HF) diet; a mix of HF diet and Bif; a mix of standard diet and Bif. Liver, mesenteric fat, epididymal fat, retroperitoneal fat, and inguinal fat, pancreas and triceps surae in all four groups of the rats were weighed, while liver steatosis and insulin sensitivity were evaluated at the end point of the study. As the number of intestinal Bifidobacterium species decreased obviously, fat pad weight and body weight increased significantly in the HF group compared with in the other three groups (P <0·05). Addition of Bif led to a reduction in body weight and fat pad weight (P <0·05). With an increase in liver weight, more severe steatosis of hepatocytes was observed in the HF group compared with in the other three groups. A significant decrease of the glucose infusion rate and pancreas weight was found in the HF group (P <0·05). This deleterious effect was alleviated when Bif was added to the diets. Bifidobacterium supplementation ameliorated visceral fat accumulation and insulin sensitivity of the metabolic syndrome in HF-diet-fed rats.

scholarly journals Systemic Oxidative Stress is Associated With Visceral Fat Accumulation and the Metabolic Syndrome

2006 ◽  
Vol 70 (11) ◽  
pp. 1437-1442 ◽  
Author(s):  
Koichi Fujita ◽  
Hitoshi Nishizawa ◽  
Tohru Funahashi ◽  
Iichiro Shimomura ◽  
Michio Shimabukuro
Keyword(s):  
Oxidative Stress ◽  
Metabolic Syndrome ◽  
Visceral Fat ◽  
Fat Accumulation ◽  
Visceral Fat Accumulation ◽  
Systemic Oxidative Stress ◽  
The Metabolic Syndrome
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