scholarly journals Heavy Metals in Leaf, Stem Bark of Neem Tree (Azadirachta indica) and Roadside Dust in Maiduguri Metropolis, Borno State, Nigeria

2012 ◽  
Vol 2 (1) ◽  
Author(s):  
Joseph Clement Akan ◽  
Lawan Bukar Inuwa ◽  
Zaynab Muhammad Chellube ◽  
Babagana Lawan
Keyword(s):  
Heavy Metals ◽  
Azadirachta Indica ◽  
Stem Bark ◽  
Neem Tree ◽  
Roadside Dust

scholarly journals Heavy Metals contents in Neem Tree (Azadirachta indica) Parts and Surroundings

2019 ◽  
Vol 3 (8) ◽  
pp. 126-130
Author(s):  
Ideisan I Abu-Abdoun ◽  
Zohuir A Al-Balawna
Keyword(s):  
Heavy Metals ◽  
Azadirachta Indica ◽  
Neem Tree

Traditional, Pharmacological and Patenting Potential of Neem (Azadirachta indica): A Review

2017 ◽  
Vol 3 (4) ◽  
pp. 383-391
Author(s):  
Mohd Asif Khan ◽  
Shashi Bhooshan Tiwari ◽  
Himanshu Gupta ◽  
Huma Noor
Keyword(s):  
Azadirachta Indica ◽  
Indian Subcontinent ◽  
National Academy Of Sciences ◽  
Neem Tree ◽  
Commercial Plant ◽  
Pharmacological Potential ◽  
Pharmacologically Active ◽  
In The Beginning ◽  
Prevention And Cure ◽  
Academy Of Sciences

Since ancient time, herbal drugs were highly used in the prevention and cure of various human illnesses. In India, Azadirachta indica being commonly known as Neem or Margosa is one of the multi-functional trees; belonging to Meliaceae family. In 1992, the US National Academy of Sciences was published a report entitled ‘Neem- a tree for solving global problems’. It is still considered as ‘village dispensary’ throughout the India. There are two species of Azadirachta which have been investigated; Azadirachta indica that is found in the Indian subcontinent and Azadirachta excelsa Kack that is homegrown to Indonesia and Philippines. A large number of pharmacologically active substances have been identified and isolated from the different parts of neem including azadirachtin, meliacin, gedunin, salanin, nimbin, valassin and various other components which are derived from these main compounds. Many different studies have been evaluated and authenticated for its various traditional and pharmacological activities like itching, leprosy, wound healing, spermicidal, anti-inflammatory, insecticidal, antidiabetic and analgesic etc. In the beginning of 1979, patenting on neem was started by CSIR to separate the active compounds from neem oil. Its great implantation fights with soil erosion, global warming, deforestations and desertification world-wide. In 2002, World Neem Conference raised the neem tree as an industrial or commercial plant. This review is going to explore comprehensively; traditional, pharmacological potential along with patenting, environmental & industrial significant of various parts of neem tree with safety concerns.

Neem tree (Azadirachta indica) extract specifically suppresses the growth of tumors in H22-bearing Kunming mice

2016 ◽  
Vol 71 (7-8) ◽  
pp. 201-208 ◽  
Author(s):  
Zhenxiang He ◽  
Cuihua Jiang ◽  
Jian Zhang ◽  
Zhiqi Yin ◽  
Zengfang Yin ◽  
...  
Keyword(s):  
Body Weight ◽  
Survival Rate ◽  
Azadirachta Indica ◽  
Normal Liver ◽  
Positive Control ◽  
High Dose ◽  
Intragastric Administration ◽  
Neem Tree ◽  
Specific Cytotoxicity ◽  
The Right

Abstract Recently, neem tree (Azadirachta indica) extract (NTE) has been reported to have various antitumor activities against gastric, breast, prostate, and skin cancer, respectively. The current study was designed to evaluate the effect of NTE on hepatic cancer in a mouse model. The possible side effects elicited by NTE were also evaluated. The components in NTE were analyzed by liquid chromatography–mass spectrometry (LC-MS). H22 cells-bearing Kumming mice were generated by injecting H22 cells subcutaneously into the right forelimb armpit of the mice. Then the mice were treated daily for 27 days with NTE (150, 300, and 600 mg/kg body weight) by intragastric administration, using carboxymethyl cellulose (CMC, 1%) as blank control and cyclophosphamide (CTX, 20 mg/kg) as positive control. The antitumor effect of NTE was evaluated by assessment of survival rate, body weight, tumor volume and weight, tumor histology, thymus and spleen indexes, and liver histology. The tumor weight and volume in groups of NTE and CTX were significantly lower than those in the CMC group. The survival rate in the NTE group receiving the high dose (600 mg/kg) was significantly higher than that in the CTX and CMC groups. Compared with CTX, NTE was observed to have a tumor-specific cytotoxicity without impairing the normal liver tissue. Additionally, the higher indexes of thymus and spleen indicated that NTE could facilitate the growth of immune organs. The results indicate that NTE is a promising candidate for the antitumor treatment with high efficacy and safety.

HPTLC Fingerprint Profile and Preliminary Phyto-chemical analysis of Nimba (Azadirachta indica) Leaf and Stem Bark

2016 ◽  
Vol 8 (2) ◽  
pp. 65
Author(s):  
Ravi Sunder Prajapati ◽  
G.P. Richhariya ◽  
I. P. Tripathi ◽  
Ravindra Singh ◽  
Manoj Tripathi
Keyword(s):  
Chemical Analysis ◽  
Azadirachta Indica ◽  
Stem Bark
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