Vitamin D Supplementation in Patients with Iron Deficiency Anaemia: A Systematic Review and a Meta-Analysis

2018 ◽  
Vol 10 (1) ◽  
pp. 01-10 ◽  
Author(s):  
Roopa Satyanarayan Basutkar ◽  
Tenzin Tsundue ◽  
Hema Siva ◽  
Anju Rose ◽  
Sivasankaran Ponnusankar
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Meta Analysis ◽  
Vitamin D Supplementation ◽  
Deficiency Anaemia

scholarly journals Iron stores in pregnant women with sickle cell disease: a protocol for a systematic review and meta-analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e026497 ◽  
Author(s):  
Desmond Aroke ◽  
Benjamin Momo Kadia ◽  
Tsi Njim
Keyword(s):  
Systematic Review ◽  
Sickle Cell Disease ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Iron Deficiency Anaemia ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Cell Disease ◽  
Deficiency Anaemia

IntroductionSickle cell disease (SCD) is the most common inherited disease worldwide. The greatest disease burden is seen in sub-Saharan Africa. Early diagnosis and improved care of people living with SCD have led to an increase in the number of women with SCD reaching the reproductive age. Iron deficiency anaemia remains the most common cause of anaemia in pregnancy, affecting 51%–63% of pregnancies in Africa. However, the unavailability of guidelines on supplementation of iron in this pregnant subpopulation often leaves clinicians in a fix. We propose to conduct the first systematic review and possibly a meta-analysis on the prevalence, associated factors and maternal/fetal outcomes of iron deficiency anaemia among pregnant women with SCD.Methods and analysisWe will search the following electronic databases for studies on the iron status of pregnant women with SCD: PubMed, MEDLINE, EMBASE, Google Scholar, African Journals Online, African Index Medicus, Popline and the Cochrane Library. After the selection of eligible studies from the search output, review of full text, data extraction and data synthesis will be performed. Studies obtained from the review shall be evaluated for quality, risk of bias and heterogeneity. Appropriate statistical methods shall be used to pool prevalence estimates for matching studies globally and in subpopulations. This protocol has been reported as per the 2015 guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols.Ethics and disseminationThere is no requirement for ethical approval as the proposed study will use published data. The findings of this study will be published in a peer-reviewed journal and will be presented at conferences.Trial registration numberCRD42018109803.

Intravenous or oral iron for treating iron deficiency anaemia during pregnancy: systematic review and meta‐analysis

2019 ◽  
Vol 211 (8) ◽  
pp. 367-373 ◽  
Author(s):  
Alaa Qassim ◽  
Rosalie M Grivell ◽  
Amanda Henry ◽  
Giselle Kidson‐Gerber ◽  
Antonia Shand ◽  
...  
Keyword(s):  
Systematic Review ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Meta Analysis ◽  
Oral Iron ◽  
Deficiency Anaemia

PREVALENCE OF IRON-DEFICIENCY ANAEMIA IN BRAZILIAN CHILDREN UNDER FIVE YEARS OF AGE: A SYSTEMATIC REVIEW AND META-ANALYSIS

2020 ◽  
pp. 1-29
Author(s):  
Victor N.C. Silveira ◽  
Carolina A. Carvalho ◽  
Poliana C.A.F. Viola ◽  
Elma I.S. Magalhães ◽  
Luana L. Padilha ◽  
...  
Keyword(s):  
Systematic Review ◽  
Iron Deficiency ◽  
Low Income ◽  
Iron Deficiency Anaemia ◽  
Meta Analysis ◽  
Deficiency Anaemia ◽  
Children Under Five ◽  
Under Five ◽  
Pooled Prevalence ◽  
Brazilian Children

Abstract Iron-deficiency anaemia is considered an important public health problem both in wealthier countries and in those of medium and low income, especially in children under five years of age. The shortage of studies with national representativity in medium income countries, such as Brazil, prevents the knowledge of the current situation and its associated factors. We conducted a systematic review and meta-analysis to estimate the pooled prevalence of iron-deficiency anaemia in Brazilian children under five years of age and determined the factors involved in the variability of the estimates of prevalence. We collected 57 studies from the databases MEDLINE, LILACS, and Web of Science, along with the reference lists of included articles. We contacted authors for unpublished data. We did not restrict publication timespan and language. This systematic review and meta-analysis were reported according to the guidelines by PRISMA. The pooled prevalence of anaemia in children under five years of age in Brazil was 40.2% (CI95%: 36.0-44.8). The age range of the child and the period of data collection were associated with the anaemia prevalence. The pooled prevalence of anaemia was higher in children under 24 month of age (53.5% vs 30.7%; p<0.001) and in studies with data collected before 2004 (51.8% vs 32.6%; p=0.001). The efforts made by Brazilian government were successful in the reduction of anaemia in children under five years old in Brazil in the evaluated period. However, prevalence remains beyond acceptable levels for this populational group.

Vitamin D in Basketball Players: Current Evidence and Future Directions

2021 ◽  
pp. 194173812110193
Author(s):  
Emilija Stojanović ◽  
Dragan Radovanović ◽  
Tamara Hew-Butler ◽  
Dušan Hamar ◽  
Vladimir Jakovljević
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Body Composition ◽  
Physical Performance ◽  
Bone Health ◽  
Meta Analysis ◽  
Vitamin D Supplementation ◽  
Current Evidence ◽  
Basketball Players ◽  
Level Of Evidence

Context: Despite growing interest in quantifying and correcting vitamin D inadequacy in basketball players, a critical synthesis of these data is yet to be performed to overcome the low generalizability of findings from individual studies. Objective: To provide a comprehensive analysis of data in basketball pertaining to (1) the prevalence of vitamin D inadequacy; (2) the effects of vitamin D supplementation on 25-hydroxyvitamin D [25(OH)D] concentration (and its association with body composition), bone health, and performance; and (3) crucial aspects that warrant further investigation. Data Sources: PubMed, MEDLINE, ERIC, Google Scholar, SCIndex, and ScienceDirect databases were searched. Study Selection: After screening, 15 studies were included in the systematic review and meta-analysis. Study Design: Systematic review and meta-analysis. Level of Evidence: Level 3. Data Extraction: The prevalence of vitamin D inadequacy, serum 25(OH)D, body composition, stress fractures, and physical performance were extracted. Results: The pooled prevalence of vitamin D inadequacy for 527 basketball players in 14 studies was 77% ( P < 0.001; 95% CI, 0.70-0.84). Supplementation with 4000 IU/d and 4000 IU/wk (absolute mean difference [AMD]: 25.39 nmol/L; P < 0.001; 95% CI, 13.44-37.33), as well as 10,000 IU/d (AMD: 100.01; P < 0.001; 95% CI, 70.39-129.63) vitamin D restored 25(OH)D to normal concentrations. Body composition data revealed inverse correlations between changes in serum 25(OH)D (from pre- to postsupplementation) and body fat ( r = −0.80; very large). Data concerning positive impacts of vitamin D supplementation on bone health and physical performance remain sparse. Conclusion: The high proportion of vitamin D inadequacy underscores the need to screen for serum 25(OH)D in basketball players. Although supplementation restored vitamin D sufficiency, the beneficial effects on bone health and physical performance remain sparse. Adiposity can modulate 25(OH)D response to supplementation.

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