scholarly journals Lipid Peroxidation Inhibitory Activity In vitro of Mezzetia parviflora Becc. Wood Bark Polar extract

2017 ◽  
Vol 9 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Mufidah Murdifin ◽  
Ermina Pakki ◽  
Gemini Alam ◽  
Marianti A. Manggau ◽  
Lukman Muslimin ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Inhibitory Activity ◽  
Wood Bark ◽  
Lipid Peroxidation Inhibitory Activity

IN VITRO LIPID PEROXIDATION INHIBITORY AND ANTI-ARTHRITIC ACTIVITIES OF SOME INDIAN MEDICINAL PLANTS

INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (06) ◽  
pp. 31-35
Author(s):  
A. A Rege ◽  
◽  
P. R. Juvekar ◽  
A. R. Juvekar
Keyword(s):  
Lipid Peroxidation ◽  
Liver Mitochondria ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum ◽  
Rat Liver Mitochondria ◽  
Total Phenolic ◽  
Lipid Peroxidation Inhibitory Activity ◽  
Gallic Acid Equivalent ◽  
Indian Medicinal Plants

Anti-lipid peroxidation effect of aqueous extracts of Ocimum sanctum, Tinospora cordifolia and Withania somnifera was evaluated against Fe2+-ascorbic acid-induced lipid peroxidation using rat liver mitochondria as model system, whereas, anti-arthritic activity was evaluated by proteinase inhibitory assay. O. sanctum showed potent anti-lipid peroxidation and anti-arthritic activities. T. cordifolia exhibited moderate anti-lipid peroxidation activity, but considerable anti-arthritic activity, whereas, W. somnifera revealed least lipid peroxidation inhibitory activity and considerable anti-arthritic activity. Besides, Folin-Ciocalteu reagent in terms of gallic acid equivalent achieved the total phenolic content and the trend was found to be O. sanctum > T. cordifolia > W. somnifera.

scholarly journals Inhibitory Activity of the Extract from Broussonetia papyrifera Fruits to Cellular Lipid Peroxidation in vitro

2014 ◽  
Vol 26 (1) ◽  
pp. 201-204
Author(s):  
Yang Li ◽  
Xiaoya Shang ◽  
Weining Niu ◽  
Chunlan Xu ◽  
Chuanguang Qin
Keyword(s):  
Lipid Peroxidation ◽  
Inhibitory Activity ◽  
Cellular Lipid ◽  
Broussonetia Papyrifera

scholarly journals Inhibition of microsomal lipid peroxidation by glutathione and glutathione transferases B and AA. Role of endogenous phospholipase A2

1984 ◽  
Vol 220 (1) ◽  
pp. 243-252 ◽  
Author(s):  
K H Tan ◽  
D J Meyer ◽  
J Belin ◽  
B Ketterer
Keyword(s):  
Lipid Peroxidation ◽  
Phospholipase A2 ◽  
Rat Liver ◽  
Inhibitory Activity ◽  
Liver Microsomes ◽  
Supernatant Fraction ◽  
Rat Liver Microsomes ◽  
Microsomal Lipid Peroxidation ◽  
Soluble Supernatant

Lipid peroxidation in vitro in rat liver microsomes (microsomal fractions) initiated by ADP-Fe3+ and NADPH was inhibited by the rat liver soluble supernatant fraction. When this fraction was subjected to frontal-elution chromatography, most, if not all, of its inhibitory activity could be accounted for by the combined effects of two fractions, one containing Se-dependent glutathione (GSH) peroxidase activity and the other the GSH transferases. In the latter fraction, GSH transferases B and AA, but not GSH transferases A and C, possessed inhibitory activity. GSH transferase B replaced the soluble supernatant fraction as an effective inhibitor of lipid peroxidation in vitro. If the microsomes were pretreated with the phospholipase A2 inhibitor p-bromophenacyl bromide, neither the soluble supernatant fraction nor GSH transferase B inhibited lipid peroxidation in vitro. Similarly, if all microsomal enzymes were heat-inactivated and lipid peroxidation was initiated with FeCl3/sodium ascorbate neither the soluble supernatant fraction nor GSH transferase B caused inhibition, but in both cases inhibition could be restored by the addition of porcine pancreatic phospholipase A2 to the incubation. It is concluded that the inhibition of microsomal lipid peroxidation in vitro requires the consecutive action of phospholipase A2, which releases fatty acyl hydroperoxides from peroxidized phospholipids, and GSH peroxidases, which reduce them. The GSH peroxidases involved are the Se-dependent GSH peroxidase and the Se-independent GSH peroxidases GSH transferases B and AA.

Lipid peroxidation inhibitory activity of some constituents isolated from the stem bark ofEucalyptus globulus

2000 ◽  
Vol 23 (2) ◽  
pp. 147-150 ◽  
Author(s):  
Bong-Sik Yun ◽  
In-Kyoung Lee ◽  
Jong-Pyung Kim ◽  
Sung-Hyun Chung ◽  
Gyu-Seop Shim ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Inhibitory Activity ◽  
Stem Bark ◽  
Lipid Peroxidation Inhibitory Activity

Limonoids from Meliaceae with Lipid Peroxidation Inhibitory Activity

2011 ◽  
Vol 6 (6) ◽  
pp. 1934578X1100600 ◽  
Author(s):  
Robert G. Fowles ◽  
Baldwin S. Mootoo ◽  
Russel S. Ramsewak ◽  
William F. Reynolds ◽  
Muraleedharan G. G. Nair
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Inhibitory Activity ◽  
Natural Compounds ◽  
Lipid Peroxidation Inhibitory Activity ◽  
Positive Controls

In this study the antioxidant activity of natural limonoids from Meliaceae swietenolide (1), 3,6-O,O-diacetylswietenolide (2), swietenine (3), swietemahonin G (4) and 2-hydroxyswietenine (5) were investigated along with the semisynthetic analogues (6-25) of compounds 1, 3-4. Lipid peroxidation (LPO) inhibitory assays revealed 85.6, 13.3, 77.3, 61.2 and 24.6 % inhibition for the natural compounds 1-5. Excellent antioxidant activity was seen for the semisynthetic analogues 10 (98.3 %), 16-17, 21-22 and 25 (100 %), which were more active than the positive controls BHA (91.3 %) and TBHQ (95.7 %).

QSAR Analysis of the Lipid Peroxidation Inhibitory Activity with Structure and Energetics of 36 Flavonoids Derivatives

2006 ◽  
Vol 53 (6) ◽  
pp. 1251-1261 ◽  
Author(s):  
Hsien-Ren Liao ◽  
Yeong-Sheng Chang ◽  
Ling-Ling Yang ◽  
Yu-Chun Lin ◽  
Yu-Ma Chou ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Inhibitory Activity ◽  
Qsar Analysis ◽  
Lipid Peroxidation Inhibitory Activity
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