Effect of Pioglitazone, Quercetin, and Hydroxy Citric Acid on the Lipid Profile and Lipoproteins in Experimentally Induced Non-alcoholic Steatohepatitis (NASH)

2014 ◽  
Vol 48 (1) ◽  
pp. 32-38
Author(s):  
Surapaneni Krishna Mohan ◽  
Mallika Jainu
Keyword(s):  
Citric Acid ◽  
Lipid Profile ◽  
Alcoholic Steatohepatitis ◽  
Experimentally Induced

scholarly journals Effect of Cholesterol and Niacin Supplementation on Serum Lipid Profile in Experimentally Induced Renal Dysfunction in Wistar Rats

2019 ◽  
Vol 8 (8) ◽  
pp. 1019-1028
Author(s):  
Pallavi Khajuria Pratiksha Raghuwanshi ◽  
Aditi Lal Koul Ankur Rastogi ◽  
Dibyendu Chakarborty Vishav Pratap Singh ◽  
Sumeet Kour V.S. Wazir
Keyword(s):  
Lipid Profile ◽  
Renal Dysfunction ◽  
Serum Lipid ◽  
Wistar Rats ◽  
Serum Lipid Profile ◽  
Experimentally Induced

scholarly journals Effect of Wheatgrass (Triticum aestivum) Juice on High Density Lipoprotein (HDL) Level in Experimentally Induced Dyslipidaemic Male Long Evans Rat

2015 ◽  
Vol 3 (1) ◽  
pp. 18-24
Author(s):  
Rokhsana Dil Afroz ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Md Ismail Khan ◽  
Tuhin Jahan
Keyword(s):  
Triticum Aestivum ◽  
Lipid Profile ◽  
Cholesterol Level ◽  
Hdl Cholesterol ◽  
High Density ◽  
Lipid Lowering ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Long Evans ◽  
Experimentally Induced

Background: Evidence shows that high density lipoproteins (HDLs) may exert multiple anti-atherogenic and anti-thrombotic effects that together decrease the risk of cardiovascular morbidity in hyperlipidaemic state. Experimental studies showed that fresh wheatgrass (Triticum aestivum Linn.) juice exerts lipid lowering effect as well as increases HDL-cholesterol level in rats. Objective: The present study was done to observe the effect of wheatgrass juice on serum HDL-cholesterol on experimentally induced dyslipidaemic rats evident by reduced HDL-cholesterol level. Materials and method: This experimental study was carried out in the Department of Pharmacology & Therapeutics, Dhaka Medical College, Dhaka, from July 2009 to June 2010. A total number of 48 healthy adult male Long Evans rats, age ranging from 2-3 months, and weighing from 140-200 grams were used for the present study. Six rats were taken in each group of total 8 groups treated differently with 1 control group. Rats of the first 5 groups were sacrificed at 29th day and their lipid profile was measured. Rests of the rats were sacrificed at 57th day and their lipid profile was measured. Results: Mean HDL-cholesterol of the group of rats treated with 10 mL/kg grass juice and 1% cholesterol diet, with 10 mL/kg grass juice and with 20 mL/kg grass juice were significantly increased (P<0.05, P<0.05, P<0.01 respectively). The mean HDL-cholesterol of the group treated with Atorvastatin for 28 days were also significantly increased (P<0.001).Conclusion: The present experiment showed that HDL-cholesterol level is increased by ingestion of wheat grass juice in experimental animals. Therefore, it provides the initial step for demonstrating cardio-protective effect of wheatgrass juice by increasing HDL-cholesterol level in blood in dyslipidaemic state. DOI: http://dx.doi.org/10.3329/dmcj.v3i1.22235 Delta Med Col J. Jan 2015; 3(1): 18-24

scholarly journals Grapeseed polyphenol + ∂‐tocotrienol favorably alters lipid profile in C57BL/6J mice with diet‐ induced non‐alcoholic steatohepatitis (829.28)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Melissa Mendez ◽  
Parakat Vijayagopal ◽  
Shanil Juma ◽  
Chandan Prasad ◽  
Vicky Imrhan
Keyword(s):  
Lipid Profile ◽  
Alcoholic Steatohepatitis

scholarly journals Effect of Ethanol Extract of Glycine Max (Soy Bean) on Serum Lipid Profile of Fat-Fed Hyperlipidemic Rats

2018 ◽  
Vol 10 (1) ◽  
pp. 21-26
Author(s):  
K Sharmin ◽  
R Ahmed ◽  
A Momtaz ◽  
SA Chowdhury ◽  
NA Maya ◽  
...  
Keyword(s):  
Glycine Max ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Serum Lipid Profile ◽  
Lipid Lowering ◽  
Control Group ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Experimentally Induced

Hypercholesterolemia is one of the important causes of cardiovascular disease related mortality and morbidity and recently it has become a significant issue in public health problem of developing countries. The purpose of the study was to see the effect of glycine max (soy bean) on serum lipid profile of experimentally induced hyperlipidemic rats. Hypercholesterolemia was induced by high cholesterol diet containing 1% cholesterol in olive oil. This study was done on 24 long Norwegian rats (Rattus norvegicus) weighing about 200-210 gram. For convenience, the study was divided into Experiment I and Experiment II. In experiment I, 12 rats were divided into two groups- Group A (n = 6, control group) fed on laboratory diet and Group B (n=6) fed on laboratory diet and soy bean extract for 35 days. In experiment II, the remaining 12 rats were divided into 2 groups, Group C (n=6) were fed on laboratory diet and high cholesterol diet (HCD) for 35 days and Group D (n=6) were fed laboratory diet and high cholesterol diet on initial 10 days and soy bean extract was added along with high cholesterol diet for next 25 days. Serum TC, TG, LDL-C and HDL-C were measured after 35 days. HCD increased TG, TC and LDL-C significantly in group C. Glycine max (soy bean) treated group showed that it decreased plasma TC, TG and LDL-C in experimentally induced hyperlipidemic rats but Glycine max (soy bean) did not show any significant lipid lowering effect in normolipidemic rats. The results of this experimental study indicate that Glycine max can act as a cholesterol lowering agent and thereby can improve cardiovascular functions.Bangladesh J Med Biochem 2017; 10(1): 21-26

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