scholarly journals Nanotechnology and mesenchymal stem cells with chondrocytes in prevention of partial growth plate arrest in pigs

2012 ◽  
Vol 156 (2) ◽  
pp. 128-134 ◽  
Author(s):  
Ladislav Planka ◽  
Robert Srnec ◽  
Petr Rauser ◽  
David Stary ◽  
Eva Filova ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Growth Plate

Characterisation of ovine bone marrow derived mesenchymal stem cells and autologous application to growth plate cartilage defect

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S159
Author(s):  
R.C. McCarty ◽  
S. Gronthos ◽  
A.C. Zannettino ◽  
B.K. Foster ◽  
C.J. Xian
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Growth Plate ◽  
Cartilage Defect ◽  
Growth Plate Cartilage

Changes in the avascular area of the meniscus using mesenchymal stem cells and growth plate chondrocytes in a pig model

2021 ◽  
Author(s):  
Ryszard Tomaszewski ◽  
Magdalena Rost‐Roszkowska ◽  
Grażyna Wilczek ◽  
Artur Gap ◽  
Łukasz Wiktor
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Growth Plate ◽  
Pig Model ◽  
Growth Plate Chondrocytes ◽  
Avascular Area

scholarly journals Prevention of Bone Bridge Formation Using Transplantation of the Autogenous Mesenchymal Stem Cells to Physeal Defects: An Experimental Study in Rabbits

2007 ◽  
Vol 76 (2) ◽  
pp. 253-263 ◽  
Author(s):  
L. Plánka ◽  
A. Nečas ◽  
P. Gál ◽  
H. Kecová ◽  
E. Filová ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Growth Plate ◽  
Valgus Deformity ◽  
Type I ◽  
Repair Capacity ◽  
Left Femur ◽  
Bone Bridge ◽  
Bridge Formation ◽  
The Right

Physeal cartilage is known to have poor self-repair capacity after injury. Evaluation of the ability of cultured mesenchymal stem cells to repair damaged physis is the topic of current research. In 10 immature New Zealand white rabbits autogenous mesenchymal stem cells were transplanted into a iatrogenic physeal defect in a lateral portion of the distal growth plate of the right femur. The same defect without stem cells transplantation in the left femoral distal physis served as a control. In our study, we used our own technique of implantation of MSCs with a newly modified gel scaffold (New Composite Hyaluronate/Collagen Type I/Fibrin Scaffold). The rabbits were euthanized 4 months after transplantation. Bone length discrepancy and valgus deformity were measured from femoral radiographs. Healing of the defect was investigated histologically. The ability of mesenchymal stem cells to survive and promote cartilage healing in the physeal defect was assessed by immunofluorescence. Average difference in femur length measured from surgery to euthanasia (4 months) was 0.61 ± 0.19 cm after preventive transplantation of MSCs in the right femur, but only 0.11 ± 0.07 cm in the left femur. Average angular (valgus) deformity of the right femur with MSCs preventively transplanted to iatrogenically damaged distal femoral physis was 1.2 ± 0.72 °. Valgus deformity in the left femur was 5.4 ± 2.5 °. Prophylactic transplantation of autogenous mesenchymal stem cells to iatrogenically damaged distal growth plate of the rabbit femur prevented a bone bridge formation and resulted in healing of the physeal defect with hyaline cartilage. Immunofluorescence examination showed that the chondrocytes newly formed in growth zone are the result of implanted MSCs differentiation. Femur growth in traumatized physis was maintained even after transplantation of autogenous MSCs. As compared with the opposite femur (with physeal defect but without transplanted MSCs), the bone showed no significant shortening or valgus deformity (p = 0.018).

Proliferation and multi-differentiation potentials of human mesenchymal stem cells on thermoresponsive PDMS surfaces grafted with PNIPAAm

2010 ◽  
Vol 30 (6) ◽  
pp. 455-455 ◽  
Author(s):  
Dongyan Shi ◽  
Dan Ma ◽  
Feiqing Dong ◽  
Chen Zong ◽  
Liyue Liu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells

1417: Mesenchymal Stem Cells Alone or Modified with ENOS Restore Erectile Function in the Aged Rat: Cell-Based Gene Therapy for Erectile Dysfunction

2004 ◽  
Vol 171 (4S) ◽  
pp. 373-373
Author(s):  
Trinity J. Bivalacqua ◽  
Mustafa F. Usta ◽  
Hunter C. Champion ◽  
Weiwen Deng ◽  
Philip J. Kadowitz ◽  
...  
Keyword(s):  
Stem Cells ◽  
Gene Therapy ◽  
Mesenchymal Stem Cells ◽  
Erectile Dysfunction ◽  
Erectile Function ◽  
Aged Rat

Placenta mesenchymal stem cells on a chorion scaffold as a potential osteogenic graft for peripartal bone regeneration

2008 ◽  
Vol 68 (S 01) ◽  
Author(s):  
S Mohr ◽  
BC Portmann-Lanz ◽  
A Schoeberlein ◽  
R Sager ◽  
DV Surbek
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Regeneration
Sign in / Sign up

Export Citation Format

Share Document