scholarly journals Assessment Of The Factors Affecting The Clinical Performance Of Direct Posterior Restorations

2016 ◽  
Vol 37 (2) ◽  
pp. 99-106
Author(s):  
Esra Uzer Çelik ◽  
Başak Yazkan ◽  
Ayşe Tuğçe Tunaç
Keyword(s):  
Clinical Performance ◽  
Factors Affecting ◽  
Posterior Restorations

scholarly journals Machine Learning Approaches to Predict Hepatotoxicity Risk in Patients Receiving Nilotinib

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3300
Author(s):  
Jung-Sun Kim ◽  
Ji-Min Han ◽  
Yoon-Sook Cho ◽  
Kyung-Hee Choi ◽  
Hye-Sun Gwak
Keyword(s):  
Machine Learning ◽  
Risk Factors ◽  
Odds Ratio ◽  
Clinical Performance ◽  
Area Under The Curve ◽  
High Dose ◽  
Learning Approaches ◽  
Factors Affecting ◽  
H2 Blockers ◽  
Increased Risk

Background: Although nilotinib hepatotoxicity can cause severe clinical conditions and may alter treatment plans, risk factors affecting nilotinib-induced hepatotoxicity have not been investigated. This study aimed to elucidate the factors affecting nilotinib-induced hepatotoxicity. Methods: This retrospective cohort study was performed on patients using nilotinib from July of 2015 to June of 2020. We estimated the odds ratio and adjusted odds ratio from univariate and multivariate analyses, respectively. Several machine learning models were developed to predict risk factors of hepatotoxicity occurrence. The area under the curve (AUC) was analyzed to assess clinical performance. Results: Among 353 patients, the rate of patients with grade I or higher hepatotoxicity after nilotinib administration was 40.8%. Male patients and patients who received nilotinib at a dose of ≥300 mg had a 2.3-fold and a 3.5-fold increased risk for hepatotoxicity compared to female patients and compared with those who received <300 mg, respectively. H2 blocker use decreased hepatotoxicity by 11.6-fold. The area under the curve (AUC) values of machine learning methods ranged between 0.61–0.65 in this study. Conclusion: This study suggests that the use of H2 blockers was a reduced risk of nilotinib-induced hepatotoxicity, whereas male gender and a high dose were associated with increased hepatotoxicity.

scholarly journals Clinical Performance of a Bioactive Restorative Material vs a Glass Hybrid Restorative in Posterior Restorations in High-risk Caries Patients

2021 ◽  
Vol 12 (4) ◽  
pp. 292-300
Author(s):  
Hassan Hassanein ◽  
Mai Akah ◽  
Heba Hamza ◽  
Mona M Eissa ◽  
Mai M Yousry ◽  
...  
Keyword(s):  
High Risk ◽  
Clinical Performance ◽  
Restorative Material ◽  
Posterior Restorations

Early clinical performance of resin cements in glass-ceramic posterior restorations in adult vital teeth: A systematic review and meta-analysis

2020 ◽  
Vol 123 (1) ◽  
pp. 61-70
Author(s):  
Samantha Jéssica Lopes Sousa ◽  
Deborah Lousan do Nascimento Poubel ◽  
Liliana Vicente Melo de Lucas Rezende ◽  
Fabiana Tolentino Almeida ◽  
Isabela Porto de Toledo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Glass Ceramic ◽  
Clinical Performance ◽  
Meta Analysis ◽  
Resin Cements ◽  
Posterior Restorations

Clinical performance and factors affecting the physical fit of a soft toric frequent replacement contact lens

2002 ◽  
Vol 85 (6) ◽  
pp. 350-357 ◽  
Author(s):  
Miu Kit Wong BScHons Optom ◽  
Tsui Tsui Lee BScHons Optom ◽  
Man Tat Poon BScHons Optom ◽  
Pauline Cho PhD
Keyword(s):  
Contact Lens ◽  
Clinical Performance ◽  
Factors Affecting

scholarly journals Ageing of Dental Composites Based on Methacrylate Resins—A Critical Review of the Causes and Method of Assessment

Polymers ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 882 ◽  
Author(s):  
Agata Szczesio-Wlodarczyk ◽  
Jerzy Sokolowski ◽  
Joanna Kleczewska ◽  
Kinga Bociong
Keyword(s):  
Clinical Performance ◽  
Dental Materials ◽  
Fatigue Tests ◽  
Dental Composite ◽  
Ageing Process ◽  
Inorganic Filler ◽  
Factors Affecting ◽  
Dental Resins ◽  
Oral Environment

The paper reviews the environmental factors affecting ageing processes, and the degradation of resins, filler, and the filler-matrix interface. It discusses the current methods of testing materials in vitro. A review of literature was conducted with the main sources being PubMed. ScienceDirect, Mendeley, and Google Scholar were used as other resources. Studies were selected based on relevance, with a preference given to recent research. The ageing process is an inherent element of the use of resin composites in the oral environment, which is very complex and changes dynamically. The hydrolysis of dental resins is accelerated by some substances (enzymes, acids). Bonds formed between coupling agent and inorganic filler are prone to hydrolysis. Methods for prediction of long-term behaviour are not included in composite standards. Given the very complex chemical composition of the oral environment, ageing tests based on water can only provide a limited view of the clinical performance of biomaterial. Systems that can reproduce dynamic changes in stress (thermal cycling, fatigue tests) are better able to mimic clinical conditions and could be extremely valuable in predicting dental composite clinical performance. It is essential to identify procedure to determine the ageing process of dental materials.

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