scholarly journals Leiomyosarcoma of the epididymis: 2 cases and review of the literature

2013 ◽  
Vol 5 (6) ◽  
pp. 121
Author(s):  
Victor T.H. Yuen ◽  
Shane D. Kirby ◽  
Young Chi Woo
Keyword(s):  
Blood Flow ◽  
Differential Diagnosis ◽  
Spermatic Cord ◽  
Community Hospital ◽  
Primary Treatment ◽  
High Ligation ◽  
High Grade ◽  
Review Of The Literature ◽  
Important Differential Diagnosis

Paratesticular leiomyosarcomas are rare. We report two cases ofleiomyosarcoma of the epididymis diagnosed and treated in aregional community hospital in Canada in 2009 and 2010. Bothpatients were males of ages 58 and 75, respectively. They presentedwith painless masses which, on ultrasonography, appeared to besolid masses demonstrating blood flow. Each patient underwenttrans-scrotal resection of the affected epididymis. Pathologicalexamination of trans-scrotal epididymectomy specimens confirmedthe diagnosis of high-grade leiomyosarcoma. Leiomyosarcoma isan important differential diagnosis for paratesticular masses in theelderly male; the primary treatment is radical inguinal orchiectomywith high ligation of the spermatic cord.

scholarly journals Paratesticular sarcomas: a case series and literature review

2019 ◽  
Vol 11 ◽  
pp. 175628721881802 ◽  
Author(s):  
Robert Anthony Keenan ◽  
Aisling U. Nic An Riogh ◽  
Andrea Stroiescu ◽  
Adrian Fuentes ◽  
Joan Heneghan ◽  
...  
Keyword(s):  
Spermatic Cord ◽  
Case Series ◽  
Radical Resection ◽  
High Ligation ◽  
High Grade ◽  
Soft Tissue Tumours ◽  
Rare Tumours ◽  
Well Differentiated ◽  
Grade One ◽  
Scrotal Trauma

Paratesticular soft tissue tumours are remarkably rare entities, with malignant subtypes accounting for approximately 30%. Due to the paucity of cases, a consensus on the best treatment has not yet been reached, presenting a diagnostic and therapeutic challenge for clinicians. Although rare, three such cases presented to the care of our institution serving a population of approximately 400,000 in the space of 13 months. These were three gentlemen, aged 54, 82 and 86 years old, presenting with left sided testicular swellings. Ultrasound in each case confirmed an extratesticular mass. Only the second gentleman complained of associated pain, however he had experienced scrotal trauma in the preceding weeks. Only one patient had suspicions of metastatic disease, with a 9 mm pulmonary nodule on computed tomography. All patients underwent a radical inguinal orchidectomy with high ligation of the spermatic cord, in keeping with best accepted guidelines. Histology confirmed a well-differentiated liposarcoma, a dedifferentiated liposarcoma and a leiomyosarcoma respectively, all high grade. One gentleman returned to theatre for re-excision of margins. Our case series emphasises the need for full multidisciplinary team specialist sarcoma input, as well as radical resection with judicious margins in order to reduce the risk of local recurrence, in the treatment of these rare tumours.

scholarly journals Isolated Ventricular Noncompaction Syndrome in a Nigerian Male: Case Report and Review of the Literature

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Indrani S. Bhattacharya ◽  
Marc Dweck ◽  
Andrew Gardner ◽  
Mark Jones ◽  
Mark Francis
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Cardiac Failure ◽  
Facial Dysmorphism ◽  
Review Of The Literature ◽  
Ventricular Noncompaction ◽  
Important Differential Diagnosis

Isolated ventricular non-compaction cardiomyopathy (IVNC) is a rare, morphologically distinct primary genetic cardiomyopathy, which is now gaining prominence as an important differential diagnosis in patients presenting with cardiac failure. We describe a case report of a Nigerian male with facial dysmorphism presenting with cardiac failure. This is followed by a review of the literature with focus on the diagnosis of this condition, which may be difficult especially in non-Caucasian populations.

Onychomatricoma with Onychomycosis: A Case Report and Review of the Literature

2021 ◽  
pp. 1-5
Author(s):  
Thomas Novoa Gomes Jaeger ◽  
Clarissa Canella ◽  
Andreia Pizarro Leverone ◽  
Robertha Carvalho Nakamura
Keyword(s):  
Differential Diagnosis ◽  
Benign Neoplasm ◽  
Conservative Surgery ◽  
Review Of The Literature ◽  
Fungal Treatment ◽  
Tissue Microenvironment ◽  
Important Differential Diagnosis ◽  
Aged Woman ◽  
Middle Aged Woman ◽  
Oral Terbinafine

Onychomatricoma is a primary benign neoplasm of the nail matrix. Currently, a limited number of cases have been reported, so it is still considered a rare neoplasia. However, it is debatable if this condition is underdiagnosed and underreported. Onychomycosis is an important differential diagnosis of onychomatricoma, and sometimes, both these conditions may even coexist in the same nail. As the tumor grows, tissue microenvironment is more vulnerable to dermatophytes. Probably, the altered keratin appears to be susceptible to fungal invasion. Careful clinical assessment and dermoscopic evaluation help nailing the diagnosis. Usually, total nail avulsion is the preferred therapeutic approach when they coexist. Herein, we present a case of a middle-aged woman with onychomycosis and onychomatricoma affecting a single fingernail. The proposed therapy was oral terbinafine for 6 months followed by a conservative surgery. There were dramatic changes in dermoscopic features after fungal treatment, which, to our knowledge, have not been previously reported.

Langerhans Cell Histiocytosis of the Adult Cervical Spine: A Case Report and Literature Review

2018 ◽  
Vol 80 (01) ◽  
pp. 049-052 ◽  
Author(s):  
Ekkehard Hewer ◽  
Christian Ulrich ◽  
Ralph Schär
Keyword(s):  
Differential Diagnosis ◽  
Cervical Spine ◽  
Langerhans Cell Histiocytosis ◽  
Osteolytic Lesion ◽  
Rare Condition ◽  
Langerhans Cell ◽  
Review Of The Literature ◽  
Young Adult Patient ◽  
Important Differential Diagnosis

AbstractA 36-year-old man was diagnosed with Langerhans cell histiocytosis (LCH) of the cervical spine with a unifocal expansive osteolytic lesion of C4. The surgical management with a 2-year follow-up and a review of the literature on LCH of the cervical spine are presented. Although a rare condition, LCH is an important differential diagnosis of any osteolytic lesion in the cervical spine with localized pain in a young adult patient. Review of the literature suggests a higher prevalence of LCH lesions affecting the cervical spine as compared with the thoracic or lumbar spine than historically reported.

scholarly journals Giant Phyllodes Tumor: A Case Report and Review of the Literature?

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Bueno Carolina ◽  
Steim Jéssica ◽  
Roque Fernanda ◽  
Sato Alan ◽  
Chambô Danielle ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Perineural Invasion ◽  
Standard Treatment ◽  
Immunohistochemical Analysis ◽  
Phyllodes Tumor ◽  
Left Breast ◽  
Definitive Diagnosis ◽  
High Grade ◽  
Review Of The Literature ◽  
Malignant Phyllodes Tumor

Phyllodes tumor is a rare, fast-growing, fibroepithelial neoplasm of the breast that can be classified as benign, borderline or malignant. The case reported here refers to a 25-year old patient with a lump on her left breast that grew rapidly in the postpartum period, reaching 21 cm in size. Core biopsy and immunohistochemical analysis indicated a diagnosis of high-grade phyllodes tumor. The patient underwent mastectomy of the left breast followed by breast reconstruction. Histopathology confirmed a malignant phyllodes tumor with chondrosarcomata’s and fibrosarcomatous differentiation and no angiolymphatic or perineural invasion. Phyllodes tumors are generally benign and differential diagnosis is usually made with fibroadenomas; however, clinical differentiation can be difficult in some cases. The definitive diagnosis is achieved by histopathology, which is able to differentiate benign from malignant forms of the disease. Standard treatment consists of local excision, with mastectomy being necessary in cases of borderline, large, malignant or recurrent tumors.

scholarly journals High Grade Myofibroblastic Sarcoma of Paratesticular Soft Tissues

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Ioannis Anastasiou ◽  
Panagiotis K. Levis ◽  
Ioannis Katafigiotis ◽  
Georgios Karaolanis ◽  
Viktoria-Varvara Palla ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Case Report ◽  
Soft Tissue ◽  
Spermatic Cord ◽  
Soft Tissues ◽  
High Ligation ◽  
High Grade ◽  
Myofibroblastic Sarcoma ◽  
High Incidence ◽  
Painful Mass

Tumors of the paratesticular region most often arise from the soft tissue surrounding the spermatic cord and the epididymis or from the soft tissue (dartos muscle) of the scrotal wall. Paratesticular tumors, despite their rarity, present a high incidence of malignancy (30%), and the therapeutic approach of choice is surgical resection with negative margin. The grade, the histology type, the presence of metastases during the diagnosis, the size of the tumor, the age of the patients, and the surgical margins are all important prognostic factors. We present a case report of a 86-year-old patient with a high grade paratesticular and scrotum sarcoma of soft tissues which was presented as a hard painful mass of the scrotum. The patient was subjected to high ligation of the spermatic cord and received no further treatment and 6 months after the operation no local or systematic recurrence was observed.

Isolated tuberculous monoarthritis, an important differential diagnosis in juvenile oligoarthritis

2003 ◽  
Vol 28 (05) ◽  
Author(s):  
T Froehlich ◽  
K Benz ◽  
S Weiss ◽  
J Forst ◽  
W Rascher
Keyword(s):  
Differential Diagnosis ◽  
Important Differential Diagnosis
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