scholarly journals High Grade Myofibroblastic Sarcoma of Paratesticular Soft Tissues

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Ioannis Anastasiou ◽  
Panagiotis K. Levis ◽  
Ioannis Katafigiotis ◽  
Georgios Karaolanis ◽  
Viktoria-Varvara Palla ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Case Report ◽  
Soft Tissue ◽  
Spermatic Cord ◽  
Soft Tissues ◽  
High Ligation ◽  
High Grade ◽  
Myofibroblastic Sarcoma ◽  
High Incidence ◽  
Painful Mass

Tumors of the paratesticular region most often arise from the soft tissue surrounding the spermatic cord and the epididymis or from the soft tissue (dartos muscle) of the scrotal wall. Paratesticular tumors, despite their rarity, present a high incidence of malignancy (30%), and the therapeutic approach of choice is surgical resection with negative margin. The grade, the histology type, the presence of metastases during the diagnosis, the size of the tumor, the age of the patients, and the surgical margins are all important prognostic factors. We present a case report of a 86-year-old patient with a high grade paratesticular and scrotum sarcoma of soft tissues which was presented as a hard painful mass of the scrotum. The patient was subjected to high ligation of the spermatic cord and received no further treatment and 6 months after the operation no local or systematic recurrence was observed.

scholarly journals High‐grade myofibroblastic sarcoma of the pleura: A case report and literature review

2020 ◽  
Vol 11 (10) ◽  
pp. 3011-3014
Author(s):  
Ruizhi Zhao ◽  
Jianyang Wang ◽  
Hongtu Zhang ◽  
Yihebali Chi ◽  
Nan Bi
Keyword(s):  
Case Report ◽  
Literature Review ◽  
High Grade ◽  
Myofibroblastic Sarcoma

scholarly journals Rhabdomyosarcoma of the Oral Cavity: A Case Report

2011 ◽  
Vol 05 (03) ◽  
pp. 340-343 ◽  
Author(s):  
Ozkan Miloglu ◽  
Sare Sipal Altas ◽  
Mustafa Cemil Buyukkurt ◽  
Burak Erdemci ◽  
Oguzhan Altun
Keyword(s):  
Skeletal Muscle ◽  
Case Report ◽  
Soft Tissue ◽  
Oral Cavity ◽  
Head And Neck ◽  
Soft Tissues ◽  
Neck Region ◽  
Childhood And Adolescence ◽  
Head And Neck Region ◽  
The Common

ABSTRACTRhabdomyosarcoma (RMS), a tumor of skeletal muscle origin, is the most common soft tissue sarcoma encountered in childhood and adolescence. The common sites of occurrence are the head and neck region, genitourinary tract, retroperitonium, and, to a lesser extent, the extremities. In the head and neck region, the most commonly affected sites are the orbit, paranasal sinuses, soft tissues of the cheek, and the neck. RMS is relatively uncommon in the oral cavity, and the involvement of the jaws is extremely rare. Here, we report a case of oral RMS in a 13-year-old child and describe the clinical, radiological, histopathological, and immunohistochemical findings. (Eur J Dent 2011;5:340-343)

Prognostic Factors for Children and Adolescents With Surgically Resected Nonrhabdomyosarcoma Soft Tissue Sarcoma: An Analysis of 121 Patients Treated at St Jude Children's Research Hospital

1999 ◽  
Vol 17 (12) ◽  
pp. 3697-3705 ◽  
Author(s):  
Sheri L. Spunt ◽  
Catherine A. Poquette ◽  
Yasmeen S. Hurt ◽  
Alvida M. Cain ◽  
Bhaskar N. Rao ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Tumor Size ◽  
Primary Tumor ◽  
Distant Recurrence ◽  
High Grade ◽  
Tumor Site ◽  
Primary Tumor Site ◽  
Positive Surgical Margins

PURPOSE: The rarity and heterogeneity of pediatric nonrhabdomyosarcoma soft tissue sarcoma (NRSTS) has precluded meaningful analysis of prognostic factors associated with surgically resected disease. To define a population of patients at high risk of treatment failure who might benefit from adjuvant therapies, we evaluated the relationship between various clinicopathologic factors and clinical outcome of children and adolescents with resected NRSTS over a 27-year period at our institution. PATIENTS AND METHODS: We analyzed the records of 121 consecutive patients with NRSTS who underwent surgical resection between August 1969 and December 1996. Demographic data, tumor characteristics, treatment, and outcomes were recorded. Univariate and multivariate analyses of prognostic factors for survival, event-free survival (EFS), and local and distant recurrence were performed. RESULTS: At a median follow-up of 9.2 years, 5-year survival and EFS rates for the entire cohort were 89% ± 3% and 77% ± 4%, respectively. In univariate models, positive surgical margins (P = .004), tumor size ≥ 5 cm (P < .001), invasiveness (P = .002), high grade (P = .028), and intra-abdominal primary tumor site (P = .055) adversely affected EFS. All of these factors except invasiveness remained prognostic of EFS and survival in multivariate models. Positive surgical margins (P = .003), intra-abdominal primary tumor site (P = .028), and the omission of radiation therapy (P = .043) predicted local recurrence, whereas tumor size ≥ 5 cm (P < .001), invasiveness (P < .001), and high grade (P = .004) predicted distant recurrence. CONCLUSION: In this largest single-institution analysis of pediatric patients with surgically resected NRSTS, we identified clinicopathologic features predictive of poor outcome. These variables should be prospectively evaluated as risk-adapted therapies are developed.

scholarly journals Paratesticular Leiomyosarcoma: A Case Report

2013 ◽  
Vol 52 (191) ◽  
Author(s):  
Vijaya Patil ◽  
Ashish Verma ◽  
Ravindra S. Pattar ◽  
Sanjay Nandar
Keyword(s):  
Case Report ◽  
Local Recurrence ◽  
Surgical Procedures ◽  
Distant Metastasis ◽  
Spermatic Cord ◽  
High Ligation ◽  
History Of ◽  
Radical Orchiectomy

Paratesticularleiomyosarcomas are rare neoplasms. Radical orchidectomy and high ligation of cordfollowed by surveillance is the treatment of choice. Here we report a 73-year-old man who presentedwith a 2-year history of painless lump in the left hemiscrotum. A left radical orchiectomy with highligation of the spermatic cord was performed. The histo-pathological and immunohistochemistryevaluation revealed a moderately differentiated leiomyosarcoma of paratesticular region. Thepatient is still alive with no evidence of local recurrence and distant metastasis after seven years offollow-up._______________________________________________________________________________________Keywords: leiomyosarcoma; spermatic cord; paratesticular; surgical procedures.

Overgrowth of soft tissues after transplantation of a connective tissue graft for the treatment of gingival recession

2020 ◽  
Vol 13 (12) ◽  
pp. e238816
Author(s):  
Igor Ashurko ◽  
Eduard Levonian ◽  
Ilia Dementev ◽  
Svetlana Tarasenko
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Connective Tissue ◽  
Gold Standard ◽  
Hard Palate ◽  
Soft Tissues ◽  
Gingival Recession ◽  
Connective Tissue Graft ◽  
Tissue Graft

The application of free connective tissue graft (CTG) is the gold standard in the treatment of gingival recession in the area of teeth and implants. The aim of this case report is to demonstrate a possible mucosal overgrowth complication in the soft tissue grafting area. A 24-year-old patient underwent the treatment of gingival recession in the tooth 2.3 region by an envelope technique using a free CTG from the hard palate region. Seven years after the surgery, a mucosal overgrowth was observed, which developed asymptomatically and did not cause any problems to the patient.

scholarly journals Paratesticular sarcomas: a case series and literature review

2019 ◽  
Vol 11 ◽  
pp. 175628721881802 ◽  
Author(s):  
Robert Anthony Keenan ◽  
Aisling U. Nic An Riogh ◽  
Andrea Stroiescu ◽  
Adrian Fuentes ◽  
Joan Heneghan ◽  
...  
Keyword(s):  
Spermatic Cord ◽  
Case Series ◽  
Radical Resection ◽  
High Ligation ◽  
High Grade ◽  
Soft Tissue Tumours ◽  
Rare Tumours ◽  
Well Differentiated ◽  
Grade One ◽  
Scrotal Trauma

Paratesticular soft tissue tumours are remarkably rare entities, with malignant subtypes accounting for approximately 30%. Due to the paucity of cases, a consensus on the best treatment has not yet been reached, presenting a diagnostic and therapeutic challenge for clinicians. Although rare, three such cases presented to the care of our institution serving a population of approximately 400,000 in the space of 13 months. These were three gentlemen, aged 54, 82 and 86 years old, presenting with left sided testicular swellings. Ultrasound in each case confirmed an extratesticular mass. Only the second gentleman complained of associated pain, however he had experienced scrotal trauma in the preceding weeks. Only one patient had suspicions of metastatic disease, with a 9 mm pulmonary nodule on computed tomography. All patients underwent a radical inguinal orchidectomy with high ligation of the spermatic cord, in keeping with best accepted guidelines. Histology confirmed a well-differentiated liposarcoma, a dedifferentiated liposarcoma and a leiomyosarcoma respectively, all high grade. One gentleman returned to theatre for re-excision of margins. Our case series emphasises the need for full multidisciplinary team specialist sarcoma input, as well as radical resection with judicious margins in order to reduce the risk of local recurrence, in the treatment of these rare tumours.

scholarly journals Injection-Site Sarcoma in a Dog: Clinical and Pathological Findings

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Terry M. Jacobs ◽  
Cathy E. Poehlmann ◽  
Matti Kiupel
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Injection Site ◽  
Labrador Retriever ◽  
High Grade ◽  
Pathological Findings ◽  
Adjunct Treatment ◽  
Positive Expression ◽  
High Grade Sarcoma

This case report documents the clinical and pathological findings in a dog that rapidly developed a high-grade sarcoma at the site of multiple vaccinations and follows the response to surgery and adjunct treatment with toceranib. An 11-year-old female spayed Labrador Retriever presented with dorsocervical subcutaneous masses at the injection site three weeks after receiving DA2PP-Lepto, Rabies, and Bordetella vaccinations. A high-grade soft tissue sarcoma was diagnosed microscopically and immunohistochemistry revealed positive expression of VEGFr, PDGFr, SCF, and EGFR. Repeat surgical resections and targeted treatment with toceranib resulted in a stable remission for nearly two years.

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