scholarly journals Depression and catastrophizing predict suicidal ideation in tertiary care patients with interstitial cystitis/bladder pain syndrome

2016 ◽  
Vol 10 (11-12) ◽  
pp. 383 ◽  
Author(s):  
Dean A. Tripp ◽  
J. Curtis Nickel ◽  
Adrijana Krsmanovic ◽  
Michel Pontari ◽  
Robert Moldwin ◽  
...  

Introduction: We sought to evaluate psychosocial factors as predictors of suicidal ideation (SI) in a tertiary care outpatient sample of women suffering from interstitial cystitis/bladder pain syndrome(IC/BPS).Methods: The patients are women managed at tertiary care centres (n=190). Controls were recruited from the community (n=117). Both groups completed questionnaires on demographics, pain (McGill Pain Questionnaire), IC/BPS symptoms, and psychological variables. Univariate and multivariate hierarchical regression modelling was conducted to examine the strength of associations and unique effects of psychosocial variables on patient SI.Results: Compared to 6% in healthy controls, 23% of patients endorsed SI in the past two weeks. Correlations between SI, depression, and catastrophizing across controls and cases show that forcontrols, SI is associated with greater pain (0.31; p<0.01) and depression only (0.59; p<0.01). For tertiary care centre cases, SI is associated with pain (0.24; p<0.01), depression (0.64; p<0.01), and catastrophizing (0.35; p<0.01). Regression analyses indicated that psychosocial variables accounted for a significant amount of variance over and above IC/BPS symptoms. Catastrophizing (i.e., helplessness) about pain and depression were significant univariate predictors of SI, but only depression predicted SI in multivariable analyses.Conclusions: Limitations of this study include its cross-sectional design and primarily correlation-based statistics. The present study is the first to implicate multiple psychosocial risk factors over and above IC/BPS-specific symptoms and patient pain experience in SI in women with IC/BPS. Depression in particular is uniquely important in predicting suicidality. These results support a multidisciplinary,proactive approach to IC/BPS involving not only treatment of disease symptoms, but also early detection/treatment of associated psychosocial problems.

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Dean Tripp ◽  
J Curtis Nickel ◽  
Adrijana Krsmanovic ◽  
Michel Pontari ◽  
Robert Moldwin ◽  
...  

Urology ◽  
2012 ◽  
Vol 80 (2) ◽  
pp. 280-285 ◽  
Author(s):  
Kimberly A. Hepner ◽  
Katherine E. Watkins ◽  
Marc N. Elliott ◽  
J. Quentin Clemens ◽  
Lara G. Hilton ◽  
...  

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Katherine A. Volpe ◽  
Rachel Mandelbaum ◽  
Larissa V. Rodriguez ◽  
Begüm Z. Özel ◽  
Renee Rolston ◽  
...  

2018 ◽  
Vol 13 (10) ◽  
pp. 328-33 ◽  
Author(s):  
Alison Crawford ◽  
Dean A. Tripp ◽  
J. Curtis Nickel ◽  
Lesley Carr ◽  
Robert Moldwin ◽  
...  

Introduction: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a devastating urological chronic pelvic pain condition with an unknown etiology. Evidence-based psychological strategies are becoming more successful for symptom management as we learn more about the targets for intervention. Previous research has established an indirect relationship between depression and pain through catastrophizing, but there have yet to be studies examining the emerging role of emotion regulation in this relationship. Methods: Women with IC/BPS were recruited from tertiary care clinics in Canada and the U.S. between 2013 and 2018. Patients completed questionnaires, including demographics and scores for pain, depression, catastrophizing, and difficulties in emotion regulation at baseline, six months, and one year. Serial mediation was used to test models of pain, catastrophizing, and depression. Results: A total of 135 women with IC/BPS completed all three time points. The only significant indirect path was from baseline depression to catastrophizing at six months to pain at one year (b=0.10; confidence interval [CI] 0.0049–0.2520). A followup analysis demonstrated that helplessness was the key factor of catastrophizing driving this relationship (b=0.17; CI 0.0282–0.3826). Conclusions: Reducing feelings of helplessness and increasing patient feelings of control are important ways to limit the effect of low mood on patient pain experience. De-catastrophizing interventions should be part of the referral strategy for IC/BPS symptom management.


2021 ◽  
Vol 15 (10) ◽  
Author(s):  
Alison Crawford ◽  
Abi Muere ◽  
Dean A. Tripp ◽  
J. Curtis Nickel ◽  
R. Christopher Doiron ◽  
...  

Introduction: Evidence-based psychological strategies are being used as clinicians look for helpful interventions for patients diagnosed with the enigmatic chronic urological pelvic pain condition of interstitial cystitis/bladder pain syndrome (IC/BPS). Pain and pain catastrophizing are associated with chronic pelvic pain outcomes but the longitudinal role of catastrophizing on patient pain in IC/BPS remains unknown. Methods: Women with IC/BPS were recruited from tertiary care clinics across North America and completed a battery of questionnaires, including demographics, pain, depression, catastrophizing at baseline, six months, and one year. Results: A total of 226 patients completed baseline, 183 completed the six-month survey, and 151 completed the one-year survey. Using a cross-lagged analysis, early changes in pain catastrophizing predicted later changes in pain, but not vice versa. Followup subscale analyses revealed that early changes in magnification predicted later changes in pain, early changes in pain predicted later changes in rumination, and that there was a recursive relationship between changes in helplessness and changes in pain across the study. Conclusions: Pain catastrophizing should be considered a prime target in psychological treatment for chronic pain in patients with IC/BPS, particularly those thinking styles associated with pain onset and maintenance. Future research should be conducted with constructs such as pain catastrophizing in samples prioritizing diversity of patients with IC/BPS and mechanisms as to how to effectively decrease catastrophizing.


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