scholarly journals Clinicopathological characteristics and treatment outcomes of adult

2013 ◽  
Vol 6 (1) ◽  
pp. 42 ◽  
Author(s):  
Serkan Keskin ◽  
Mert Basaran ◽  
Isin Kilicaslan ◽  
Murat Tunc ◽  
Sevil Bavbek
Keyword(s):  
Surgical Excision ◽  
Local Relapse ◽  
Clinicopathological Characteristics ◽  
Survival Times ◽  
Single Institution ◽  
Retroperitoneal Lymphadenectomy ◽  
Distant Relapse ◽  
Group I ◽  
Retroperitoneal Node

Introduction: We report our experience with 8 consecutive adults treated for paratesticular rhabdomyosarcoma (RMS) at a single institution between 2000 and 2010.Methods: After primary surgical excision, 7 patients were classified into group I according to the Intergroup Rhabdomyosarcoma Study Group (IRSG) Postsurgical Grouping Classification, and 1 patient into group IIB. Retroperitoneal node dissection was not a required staging procedure. Adjuvant chemotherapy was administered to 7 of the 8 patients. No additional radiotherapy was administered.Results: The median age at diagnosis was 24 years (range: 18-60). Embryonal histology was the most common (75%) subtype. During follow-up, 3 patients experienced local relapse and 5 distant relapse. The median progression-free and overall survival times were 17.0 ± 9.9 months (range: 5-31) and 27.3 ± 1.3 months (range: 16-58), respectively.Conclusion: Paratesticular RMS is an uncommon malignancy inadults. We confirm that patients with localized paratesticular RMS may have different prognoses. Retroperitoneal lymphadenectomy can be avoided as a treatment for paratesticular RMS after radical inguinal orchiectomy.

Could Different Follow-Up Modalities Play a Role in the Diagnosis of Asymptomatic Endometrial Cancer Relapses?: An Italian Multicentric Retrospective Analysis

2012 ◽  
Vol 22 (6) ◽  
pp. 1013-1019 ◽  
Author(s):  
Luisa Carrara ◽  
Angiolo Gadducci ◽  
Fabio Landoni ◽  
Tiziano Maggino ◽  
Giovanni Scambia ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Clinical History ◽  
Local Relapse ◽  
Cancer Surveillance ◽  
Vaginal Vault ◽  
Cytologic Examination ◽  
Distant Relapse ◽  
Asymptomatic Patients ◽  
Optimal Approach

ObjectiveTo determine current practice and to assess the value of routine follow-up procedures for endometrial cancer surveillance. To discuss whether such procedures are feasible and effective to identify asymptomatic recurrences and describe the pattern of relapse detected by procedures.MethodsThe records of 282 consecutive women with recurrent endometrial cancer treated from 1986 to 2005 were retrospectively collected in 8 Italian institutions. Primary disease, clinical history, and recurrence features and data were analyzed.ResultsThirty-five (12.4%) of 282 patients had recurrence in vaginal vault, 51 patients (18.0%) had recurrence in central pelvis, 14 patients (4.9%) had recurrence in pelvic wall, and 39 patients (13.8%) had recurrence in lymph nodes. One-hundred twenty-eight patients (45.3%) showed a distant relapse, whereas 15 patients (5.3%) developed both distant relapse and local relapse. The site of relapse influenced survival because the patients with vaginal vault recurrences lived significantly longer than the patients with recurrences in other sites. Eighty (28.4%) of the 282 patients became symptomatic and anticipated the scheduled visit, 37 (13.1 %) of the patients reported their symptoms during the follow-up meeting, and 165 (58.5 %) of the patients were asymptomatic and the diagnostic path was introduced by a planned visit or examination. Among the asymptomatic patients, the first procedure that led to further examinations was clinical visit alone for 60 (36.4%) of 165 patients, imaging for 103 patients (62.4%), and cytologic examination for 2 patients (1.2%). Symptoms at recurrence can predict survival: patients with an asymptomatic recurrence had a median survival time from relapse of 35 months versus 13 months if they had a symptomatic repetition (P = 0.0001).ConclusionsFollow-up after endometrial cancer treatment varies in Italy. In this retrospective study, women with asymptomatic recurrence have shown a better clinical outcome compared with those with symptomatic relapse. The optimal approach is actually unknown, and guidelines comparing follow-up protocols have not been established. Prospective cost-effectiveness studies are needed.

scholarly journals Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Álvaro Bengoa-González ◽  
Enrique Mencía-Gutiérrez ◽  
Beatriz Alonso-Martín ◽  
Bianca-Maria Laslău ◽  
Elena Salvador ◽  
...  
Keyword(s):  
Giant Cell ◽  
Surgical Excision ◽  
Clinicopathological Characteristics ◽  
Giant Cell Reparative Granuloma ◽  
First Case ◽  
Complete Surgical Excision ◽  
Cranial Fossa ◽  
Histopathologic Analysis ◽  
Fluid Levels

Giant cell reparative granuloma (GCRG) is a rare fibroosseous lesion uncommonly seen in the orbital area. Although benign, it is known to be recurrent and locally destructive. We report two cases of GCRG of the orbit. In both cases, computed tomography revealed a heterogeneously growing well-defined mass, arising from the roof of the orbit, affecting the cortex, and invading the orbit. In the first case, the mass extended into the anterior cranial fossa. Magnetic resonance imaging with gadolinium showed, in both cases, a cystic character of the lesion with fluid levels. The surgical treatment was performed via an upper crease incision. An ultrasonic aspirator system was used to remove the tumor tissue and its extension into cranial fossa. Careful histopathologic analysis established the diagnosis of GCRG. Symptoms resolved completely with no evidence of recurrence after a follow-up of 18 and 14 months, respectively. We present the clinicopathological and radiological findings, and we describe the surgical approach. As a rare entity, GCRG of the orbit should be considered in differential diagnosis of fibroosseous orbital masses. Complete surgical excision carries a low risk of recurrence.

scholarly journals A series Cases study of Carcinomas derived from myoepithelial cells in head and neck regions

2020 ◽  
Author(s):  
Danni Cheng ◽  
Yufang Rao ◽  
Ke Qiu ◽  
Jianqing Qiu ◽  
Yijun Dong ◽  
...  
Keyword(s):  
Head And Neck ◽  
Surgical Resection ◽  
Postoperative Radiotherapy ◽  
Surgical Excision ◽  
Myoepithelial Cells ◽  
Single Institution ◽  
Complete Surgical Excision ◽  
The Mean ◽  
Systemic Therapies

Abstract Background and Objectives: Carcinomas derived from myoepithelial cells in head and neck regions (CMCHN) are rare. The aim of this study was to demonstrate the clinical behaviors and treatment outcomes of these tumors.Methods: A retrospective review of fifteen CMCHN cases between 2002 and 2019 in a single institution was performed. Results: All of the fifteen patients (100%) underwent primary surgical resection. Eleven patients (73.3%) received conventional postoperative radiotherapy and four (26.7%) received systemic chemotherapy. Consequently, six patients (40%) had frequently recurrence after surgical resection, and seven patients (46.7%) received second or even third operations. Up to the time of last follow-up, only one patient died and the mean survival time was 15.8 years.Conclusions: Currently, complete surgical excision with or without systemic therapy is preferred, but it has limited efficacy on reducing the risk of recurrence. Thus, more effective systemic therapies are required and the researches on the mechanism of CMCHN recurrence should be encouraged.

scholarly journals Liposarcoma of the paratesticular tissue and spermatic cord: A case report

2013 ◽  
Vol 70 (7) ◽  
pp. 693-696 ◽  
Author(s):  
Filip Vukmirovic ◽  
Nihad Zejnilovic ◽  
Jovan Ivovic
Keyword(s):  
Case Report ◽  
Spermatic Cord ◽  
Malignant Tumors ◽  
Testicular Tumor ◽  
Surgical Excision ◽  
Local Relapse ◽  
Adjuvant Radiation ◽  
Rare Type ◽  
Rare Case Report

Introduction. Liposarcomas are malignant tumors derived from fat tissues. Liposarcoma of the paratesticular tissue is rare. Case report. We presented a 51-year-old man with liposarcoma of paratesticular tissue and the spermatic cord, mimicking a testicular tumor. Ultrasound examination of this scrotal mass was hyperechogenic and homogeneous and separated from the testis and epididymis. The patient was operated, and the orchidectomy was performed. Histology revealed well-differentiated lipoma-like liposarcoma of the paratesticular tissue and spermatic cord. After a 6 month follow-up the patient did not show any evidence of tumor-progression or recurrence. Conclusion. Liposarcomas of the paratesticular tissue and seminal cord represent a rare type of tumors, often misdiagnosed preoperatively. Therapy should include radical surgical excision, usually radical inguinal orchiectomy. If the margin status is in doubt, adjuvant radiation should be performed. Local relapse is common and may occur after several years, so follow- up period has to be sufficiently long.

Prognosis for dogs with nonlymphomatous, small intestinal tumors treated by surgical excision

1998 ◽  
Vol 34 (6) ◽  
pp. 451-456 ◽  
Author(s):  
J Crawshaw ◽  
J Berg ◽  
JC Sardinas ◽  
SJ Engler ◽  
WM Rand ◽  
...  
Keyword(s):  
Survival Rates ◽  
Surgical Excision ◽  
Survival Times ◽  
Intestinal Tumors ◽  
Histological Evidence ◽  
Long Term Follow Up ◽  
Small Intestinal ◽  
The One

Long-term follow-up information was obtained for 39 dogs that had undergone surgical excision of nonlymphomatous, small intestinal tumors. For all dogs evaluated in this study, the median survival time was 10 months, and the one- and two-year survival rates were 40.5% and 33.1%, respectively. There was no difference in survival times between dogs with adenocarcinomas (n=23) and dogs with leiomyosarcomas (n=16). Survival times were significantly (p less than 0.0001) shorter for dogs with histological evidence of metastases at the time of surgery (median, 3.0 months) than for dogs with no histiological evidence of metastases (median, 15.0 months).

Surgical excision of developmental retrorectal cysts: results with long-term follow-up from a single institution

2012 ◽  
Vol 64 (4) ◽  
pp. 279-284 ◽  
Author(s):  
Gennaro Rosa ◽  
Paola Lolli ◽  
Marco Vergine ◽  
Ghassan El-Dalati ◽  
Giuseppe Malleo
Keyword(s):  
Surgical Excision ◽  
Single Institution ◽  
Long Term Follow Up

Surgical Outcomes of Solid Pseudopapillary Neoplasm of the Pancreas: A Single Institution's Experience for the Last Ten Years

2012 ◽  
Vol 78 (2) ◽  
pp. 216-219 ◽  
Author(s):  
Jin Suk Lee ◽  
Hyung Joon Han ◽  
Sae Byeol Choi ◽  
Cheol Woong Jung ◽  
Tae Jin Song ◽  
...  
Keyword(s):  
Surgical Outcomes ◽  
Surgical Excision ◽  
Clinicopathological Characteristics ◽  
Good Prognosis ◽  
Pancreatic Tumors ◽  
Resection Margins ◽  
Solid Pseudopapillary Neoplasm ◽  
Complete Surgical Excision ◽  
Type Of Surgery

Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare neoplasm that accounts for about 1 to 2 per cent of all pancreatic tumors. The aim of this study was to delineate the clinicopathological characteristics and surgical outcomes of solid pseudopapillary neoplasm of the pancreas. We retrospectively reviewed the clinicopathological characteristics and surgical outcomes of 18 patients who underwent surgery for SPN of the pancreas between January 1, 2001 and November 1, 2010. The patient group was comprised of 14 females and four males and the median patient age at diagnosis was 32.4 years (range 10∼68 years). Eleven of the 18 patients were symptomatic at the time of diagnosis. The type of surgery was selected according to the location and presentation of the tumor. The resection margins were negative in all patients. One patient had distant metastasis and recurrent mass node repetitively. She underwent seven operations for recurrence of SPN during the follow-up period of 218 months. Complete surgical excision is the treatment of choice for SPN of the pancreas and can give a good prognosis. Although sometimes patients have repetitive metastases or recurrences, patients undergoing complete surgical excision of the tumor will have a good outcome.

scholarly journals Surgical excision of wrist ganglia; literature review and nine-year retrospective study of recurrence and patient satisfaction

2009 ◽  
Vol 1 (1) ◽  
pp. 5 ◽  
Author(s):  
Surjit Lidder
Keyword(s):  
Retrospective Study ◽  
Hand Surgery ◽  
Surgical Excision ◽  
Consecutive Series ◽  
Single Institution ◽  
Recurrence Rates ◽  
The Mean ◽  
Open Excision

The main options for the treatment of wrist ganglia are reassurance, aspiration, arthroscopic resection and open excision. Variations within each option have been described and the literature is clouded by widespread variability in the results reported. We present the results of our own long-term retrospective study, review the literature and question the surgical risks and demands placed on healthcare resources. A retrospective review of the surgical results of dorsal and volar wrist ganglia excision between January 1998 and March 2005 was undertaken at a single institution. Of the 152 patients in this consecutive series, 117 (77%) patients responded to a telephone questionnaire. The mean length of follow-up in this series of 117 patients was 4.2 years (range 1.5-8.7 years). The overall recurrence rate following excision of all wrist ganglia in this series was 41.8 %. When looking just at volar ganglia, the risk of recurrence is higher at 46.8%. Should the ganglion recur, the risk of developing a moderate to severely tender scar is 34.6% and the risk of developing an unsightly scar is 8.2%. This study questions the effectiveness of surgical excision in the treatment of wrist ganglia when performed by a mixture of surgeons in that the recurrence rates are very similar to the rates seen in studies that merely observe or aspirate wrist ganglia. We propose that for symptomatic ganglia, specialists in hand surgery may be more appropriate at treating such a pathology.

Long-term outcomes of lumbar microdiscectomy in the pediatric population: a large single-institution case series

2019 ◽  
Vol 24 (5) ◽  
pp. 549-557
Author(s):  
Malia McAvoy ◽  
Heather J. McCrea ◽  
Vamsidhar Chavakula ◽  
Hoon Choi ◽  
Wenya Linda Bi ◽  
...  
Keyword(s):  
Conservative Management ◽  
Functional Outcomes ◽  
Pediatric Patients ◽  
Clinical Presentation ◽  
Case Series ◽  
Csf Leak ◽  
Single Institution ◽  
The Mean

OBJECTIVEFew studies describe long-term functional outcomes of pediatric patients who have undergone lumbar microdiscectomy (LMD) because of the rarity of pediatric disc herniation and the short follow-up periods. The authors analyzed risk factors, clinical presentation, complications, and functional outcomes of a single-institution series of LMD patients over a 19-year period.METHODSA retrospective case series was conducted of pediatric LMD patients at a large pediatric academic hospital from 1998 to 2017. The authors examined premorbid risk factors, clinical presentation, physical examination findings, type and duration of conservative management, indications for surgical intervention, complications, and postoperative outcomes.RESULTSOver the 19-year study period, 199 patients underwent LMD at the authors’ institution. The mean age at presentation was 16.0 years (range 12–18 years), and 55.8% were female. Of these patients, 70.9% participated in competitive sports, and among those who did not play sports, 65.0% had a body mass index greater than 25 kg/m2. Prior to surgery, conservative management had failed in 98.0% of the patients. Only 3 patients (1.5%) presented with cauda equina syndrome requiring emergent microdiscectomy. Complications included 4 cases of postoperative CSF leak (2.0%), 1 case of a noted intraoperative CSF leak, and 3 cases of wound infection (1.5%). At the first postoperative follow-up appointment, minimal or no pain was reported by 93.3% of patients. The mean time to return to sports was 9.8 weeks. During a mean follow-up duration of 8.2 years, 72.9% of patients did not present again after routine postoperative appointments. The total risk of reoperation was a rate of 7.5% (3.5% of patients underwent reoperation for the same level; 4.5% underwent adjacent-level decompression, and one patient [0.5%] ultimately underwent a fusion).CONCLUSIONSMicrodiscectomy is a safe and effective treatment for long-term relief of pain and return to daily activities among pediatric patients with symptomatic lumbar disc disease in whom conservative management has failed.

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