Can preoperative complete blood count parameters be used in the diagnosis of patients with adnexal torsion: a case-control study

Author(s):  
Emre Tas ◽  
Huseyin Keskin ◽  
Edip Kir ◽  
Gokhan Kilic ◽  
Gizem Cetinkaya ◽  
...  
2019 ◽  
Vol 26 (1) ◽  
pp. 117-121 ◽  
Author(s):  
Yair Daykan ◽  
Rona Bogin ◽  
Merav Sharvit ◽  
Zvi Klein ◽  
Dana Josephy ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (7) ◽  
pp. e0200190 ◽  
Author(s):  
Myoung Seok Lee ◽  
Min Hoan Moon ◽  
Hyunsik Woo ◽  
Chang Kyu Sung ◽  
Sohee Oh ◽  
...  

Antibiotics ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 60
Author(s):  
Alessio Strazzulla ◽  
Sarra Abroug Ben Halima ◽  
Ibrahim Chouchane ◽  
Marwa Rezek ◽  
Marcella Pinto Stiebler ◽  
...  

Introduction: Acute pulmonary embolism (aPE) is frequently associated with coronavirus infectious disease-2019 (COVID-19) with an incidence of more than 16%. Among the new promising biomarkers of aPE, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) showed correlations with aPE prognosis. The aim of this study was to conduct an exploratory analysis to check the possible role of cell blood count (CBC) parameters as diagnostic and prognostic biomarkers of aPE in COVID-19 patients. Materials and Methods: A case control study was conducted. Two populations were compared: (i) patients hospitalised from 31 January 2020 to 30 June 2021 with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection and aPE confirmed at angio computed tomography (aCT) or pulmonary scintigraphy (COVID-19 aPE group); (ii) patients hospitalised from 31 January 2017 to 30 June 2021 without SARS-CoV-2 infection whose suspicion of aPE was excluded by aCT or pulmonary scintigraphy (no-aPE group). Results: Overall, 184 patients were included in the study, 83 in COVID-19 aPE group and 101 in no-aPE group. At the univariate analysis, COVID-19 patients with aPE had higher NLR, PLR, neutrophil and lymphocyte counts than patients without aPE (p < 0.05). No significant difference was found in mean platelet volume and platelet counts. No difference in mortality rate was detected. At the multivariate analysis, neutrophil and lymphocyte counts were both associated with diagnostic of aPE while no CBC parameters were associated with mortality at day#7. Conclusions: Neutrophiland lymphocyte counts could be predictors of the early detection of aPE in COVID-19 patients. The value of CBC indices as biomarkers of aPE in daily clinical practice needs to be investigated in further studies.


2018 ◽  
Vol 21 (8) ◽  
pp. 772-779 ◽  
Author(s):  
Daniela Ramos ◽  
Archivaldo Reche-Junior ◽  
Daniel S Mills ◽  
Priscila L Fragoso ◽  
Alexandre GT Daniel ◽  
...  

Objectives The aim of this study was to perform a case-control medical evaluation of cats from multi-cat households presenting with inappropriate latrining and spraying behavior. Methods Owners of 18 ‘spraying’ and 23 ‘latrining’ cats with normal control subjects available from the same households were recruited for a case-control study. Otherwise overtly healthy dyads (each dyad consisting of a case cat and a control cat) were brought together to the veterinary hospital of the University of São Paulo for a medical work-up (ie, physical examination, complete blood count, biochemical profile, urinalysis and urine culture, abdominal ultrasound of the urinary system and in females, where possible, cystoscopy). Results Medical problems were identified with similar frequency in the ‘sprayers’ (38.9%), ‘latriners’ (39.1%) and controls of the latrining group (26.1%), but not the controls of the spraying group (5.5%). The difference between ‘cases’ and ‘controls’ from spraying households was significant. Common potential health-related changes include renal insufficiency, cystitis and bladder lithiasis. Renal calculi, higher creatinine levels (within normal reference interval) and ‘glomerulations’ (detected during cystoscopy) were also found in the remaining sprayers and latriners that were considered clinically healthy. Post-cystoscopy, a new form of periuria occurred in two cats (one sprayer and one latriner). Conclusions and relevance These results indicate that spraying or latrining behavior in the home, as well as living with a cat that is not using the litter box as a latrine, are all associated with a higher level of urinary tract abnormalities; living with a cat that is spraying, however, does not have this association. The findings also suggest that both forms of periuria might be associated with interstitial cystitis. We therefore conclude that all cats with periuria need to be carefully evaluated medically and that treatment of latrine-related problems should consider all cats in the house, whereas spraying may be more focused on the individual displaying the problem.


2018 ◽  
Vol 98 ◽  
pp. 75-81 ◽  
Author(s):  
Caroline Mandoul ◽  
Cécile Verheyden ◽  
Fernanda Curros-Doyon ◽  
Gauthier Rathat ◽  
Patrice Taourel ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Amrit Pal Singh Rana ◽  
Manjit Kaur ◽  
B. Zonunsanga ◽  
Arun Puri ◽  
Amarjit Singh Kuka

Background.Peripheral blood count is the first investigation to be done in every patient before surgery. As strong relationship exists between cancer and immune response of the body, clinical stage at presentation and altered hematological parameters can influence the progression of cancer and vice versa.Settings and Design.It is a case control study of total 50 cases (35 cases of carcinoma breast and 15 cases of benign breast disease).Methods.A case control study was carried out; 35 cases of breast cancer patients were taken prior to surgery and chemotherapy with 15 cases of benign breast disease as control. Clinical staging according to the tumor, node, and metastasis classification (TNMc) was done and was correlated with complete blood count (CBC).Results.All the cancer patients were females with overall mean age of47.96±13.84years. Amongst all altered blood parameters, correlation of absolute lymphocytic count (pvalue 0.001) with TNMc staging was found significant. Particularly, decrease in absolute leucocytic count was observed with increase in stage of breast carcinoma.Conclusions. The stage-specific mean values of absolute lymphocytic counts of preoperative breast cancer patients can be used as an economical tool to know the evolution of disease.


Author(s):  
Salamah Parveen Imteyaz ◽  
Bijli Nanda ◽  
Manisha Jindal ◽  
Mohammad Jaseem Hassan

Introduction: Anaemia is the most prevalent haematological abnormalities associated with thyroid disorders and it is often the first sign of hypothyroidism. Pregnancy is frequently associated with anaemia; most commonly iron deficiency anaemia, followed by dimorphic anaemia. Pregnancy complicated by the development of hypothyroidism could be further associated with a higher incidence of anaemia. Aim: To determine the incidence and characteristic of anaemia in pregnancy associated with hypothyroidism. Materials and Methods: This case-control study was conducted in a Medical college hospital during January 2015 to January 2016. A total of 272 pregnant women were enrolled in the study by random sampling of all pregnant females attending Out Patient Department of our hospital. Serum Thyroid Stimulating Hormone (TSH) level was used to detect thyroid function abnormalities. Complete Blood count was done. Peripheral blood smear was stained by Leishman stain and subsequently studied under microscope for morphological classification of anaemia. Anaemia was further classified according to the Haemoglobin (Hb) level into mild, moderate and severe anaemia. Unpaired t-test, Pearson’s correlation test and chi-square test have been used in the study for analysis and comparison of various parametres. p-value <0.05 considered level of significance. Results: Out of total of 272 subjects selected for the study, 207 were euthyroid and 65 were hypothyroid. Of the 65 hypothyroid subjects, 19 were in the first trimester, 25 in the second trimester and 21 were in the third trimester. The mean TSH of euthyroid group was 2.49±1.35 mIU/L and hypothyroid group was 6.27±3.6 mIU/L (p-value 0.0001). Mean Hb of Euthyroid was 10.16 g/dL, while mean Hb of hypothyroid subjects was 8.92 g/dL and this difference was significant (p<0.001). A total of 191 (70.22%) out of 272 pregnant subject were found to be anaemic. About 131 (63.28%) out of 207 of euthyroid patients were anaemic, while 92.31% of hypothyroid patients (60 out of 65) showed anaemia. A significant association was found between Hypothyroidism and anaemia (p-value <0.0001). The mean Thyroid stimulating hormone value of anaemic patients was 3.98±1.02, which is significantly higher (p<0.0001) than TSH value of 2.65±0.98 as seen in non-anaemic patients. The majority of anaemia cases in both euthyroid and hypothyroid groups were found to be of moderate severity. Dimorphic anaemia was the most common type of anaemia morphologically in both euthyroid and hypothyroid subjects. It was also the most common type of anaemia in all three trimesters. Conclusion: The incidence of anaemia was higher in the hypothyroid group compared to the euthyroid group. Thus, it is very important to study the incidence and type of anaemia in hypothyroid pregnant females, so that appropriate early nutritional and medicinal intervention can be taken so as to prevent the morbidity and mortality in these patients.


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