scholarly journals Local Shape Analysis using MANCOVA

2009 ◽  
Author(s):  
Beatriz Paniagua ◽  
Martin Styner ◽  
Marc Macenko ◽  
Dimitrios Pantazis ◽  
Marc Niethammer

Gross shape measures such as volume have been widely used in statistical analysis of anatomical structures. Statistical shape analysis methods have emerged within the last decade to allow for a localized analysis of shape. Most shape analysis frameworks are though lacking a good statistical underpinning, as they commonly do not allow for the inclusion of independent variables such as age, gender or clinical scores. This work presents a unified method for local shape analysis that can accomodate different number of variates and contrasts. It also allows to include any number of associated variables in the statistical analysis of the data. Several cases of study are given to clarify the explanation of the different types of data that can be analyzed and the parameters that can be used to tune the program shapeAnalysisMANCOVA. This tool has been designed to interact seamlessly with the existing UNC SPHARM-PDM based shape analysis toolbox.

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Imam Wibowo, M.Si ◽  
Rusma Patriansyah

The purpose of this research is to know the information about relationship between independent variables which are training (X1) and motivation (X2) with dependent variable which is employee performance (Y) of PT. Bakrie Pipe Industries Bekasi, both simultaneously and partially. Data collected from 78 employee of PT. Bakrie Pipe Industries Operating Division randomly using Slovin formula. Then all data was analyzed by using regression and statistical analysis using F-statistic to know the influence of independent variable simultaneously and t-statistic to know the influence of independent variable partially with using SPSS Ver. 22 software. The results of this research shown that: 1). Simultaneously, training and motivation have positive influence and significant to employee performance of PT. Bakrie Pipe Industries Bekasi. 2). Partially, training has positive influence and significant to employee performance of PT. Bakrie Pipe Industries Bekasi. 3). Partially, motivation has positive influence and significant to employee performance of PT. Bakrie Pipe Industries Bekasi.


2018 ◽  
Vol 15 (12) ◽  
pp. 1151-1160 ◽  
Author(s):  
Zihan Jiang ◽  
Huilin Yang ◽  
Xiaoying Tang

Objective: In this study, we investigated the influence that the pathology of Alzheimer’s disease (AD) exerts upon the corpus callosum (CC) using a total of 325 mild cognitive impairment (MCI) subjects, 155 AD subjects, and 185 healthy control (HC) subjects. Method: Regionally-specific morphological CC abnormalities, as induced by AD, were quantified using a large deformation diffeomorphic metric curve mapping based statistical shape analysis pipeline. We also quantified the association between the CC shape phenotype and two cognitive measures; the Mini Mental State Examination (MMSE) and the Alzheimer’s Disease Assessment Scale-Cognitive Behavior Section (ADAS-cog). To identify AD-relevant areas, CC was sub-divided into three subregions; the genu, body, and splenium (gCC, bCC, and sCC). Results: We observed significant shape compressions in AD relative to that in HC, mainly concentrated on the superior part of CC, across all three sub-regions. The HC-vs-MCI shape abnormalities were also concentrated on the superior part, but mainly occurred on bCC and sCC. The significant MCI-vs-AD shape differences, however, were only detected in part of sCC. In the shape-cognition association, significant negative correlations to ADAS-cog were detected for shape deformations at regions belonging to gCC and sCC and significant positive correlations to MMSE at regions mainly belonging to sCC. Conclusion: Our results suggest that the callosal shape deformation patterns, especially those of sCC, linked tightly to the cognitive decline in AD, and are potentially a powerful biomarker for monitoring the progression of AD.


NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S99
Author(s):  
A Pepe ◽  
L Zhao ◽  
J Tohka ◽  
J Koikkalainen ◽  
J Hietala ◽  
...  

2021 ◽  
Vol 209 ◽  
pp. 106936
Author(s):  
Deniz Sigirli ◽  
Senem Turan Ozdemir ◽  
Sevda Erer ◽  
Ibrahim Sahin ◽  
Ilker Ercan ◽  
...  

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Angom Sarjubala Devi

AbstractThe level of soil organic carbon (SOC) fluctuates in different types of forest stands: this variation can be attributed to differences in tree species, and the variables associated with soil, climate, and topographical features. The present review evaluates the level of SOC in different types of forest stands to determine the factors responsible for the observed variation. Mixed stands have the highest amount of SOC, while coniferous (both deciduous-coniferous and evergreen-coniferous) stands have greater SOC concentrations than deciduous (broadleaved) and evergreen (broadleaved) tree stands. There was a significant negative correlation between SOC and mean annual temperature (MAT) and sand composition, in all types of forest stands. In contrast, the silt fraction has a positive correlation with SOC, in all types of tree stands. Variation in SOC under different types of forest stands in different landscapes can be due to differences in MAT, and the sand and silt fraction of soil apart from the type of forests.


2021 ◽  
Vol 18 ◽  
Author(s):  
Yuanyuan Wei ◽  
Nianwei Huang ◽  
Yong Liu ◽  
Xi Zhang ◽  
Silun Wang ◽  
...  

Background: Early detection of Alzheimer’s disease (AD) and its early stage, the mild cognitive impairment (MCI), has important scientific, clinical and social significance. Magnetic resonance imaging (MRI) based statistical shape analysis provides an opportunity to detect regional structural abnormalities of brain structures caused by AD and MCI. Objective: In this work, we aimed to employ a well-established statistical shape analysis pipeline, in the framework of large deformation diffeomorphic metric mapping, to identify and quantify the regional shape abnormalities of the bilateral hippocampus and amygdala at different prodromal stages of AD, using three Chinese MRI datasets collected from different domestic hospitals. Methods: We analyzed the region-specific shape abnormalities at different stages of the neuropathology of AD by comparing the localized shape characteristics of the bilateral hippocampi and amygdalas between healthy controls and two disease groups (MCI and AD). In addition to group comparison analyses, we also investigated the association between the shape characteristics and the Mini Mental State Examination (MMSE) of each structure of interest in the disease group (MCI and AD combined) as well as the discriminative power of different morphometric biomarkers. Results: We found the strongest disease pathology (regional atrophy) at the subiculum and CA1 subregions of the hippocampus and the basolateral, basomedial as well as centromedial subregions of the amygdala. Furthermore, the shape characteristics of the hippocampal and amygdalar subregions exhibiting the strongest AD related atrophy were found to have the most significant positive associations with the MMSE. Employing the shape deformation marker of the hippocampus or the amygdala for automated MCI or AD detection yielded a significant accuracy boost over the corresponding volume measurement. Conclusion: Our results suggested that the amygdalar and hippocampal morphometrics, especially those of shape morphometrics, can be used as auxiliary indicators for monitoring the disease status of an AD patient.


2021 ◽  
pp. 1-13
Author(s):  
Fernando Rebollar ◽  
Rocío Aldeco-Perez ◽  
Marco A. Ramos

The general population increasingly uses digital services, meaning services which are delivered over the internet or an electronic network, and events such as pandemics have accelerated the need of using new digital services. Governments have also increased their number of digital services, however, these digital services still lack of sufficient information security, particularly integrity. Blockchain uses cryptographic techniques that allow decentralization and increase the integrity of the information it handles, but it still has disadvantages in terms of efficiency, making it incapable of implementing some digital services where a high rate of transactions are required. In order to increase its efficient, a multi-layer proposal based on blockchain is presented. It has four layers, where each layer specializes in a different type of information and uses properties of public blockchain and private blockchain. An statistical analysis is performed and the proposal is modeled showing that it maintains and even increases the integrity of the information while preserving the efficiency of transactions. Besides, the proposal can be flexible and adapt to different types of digital services. It also considers that voluntary nodes participate in the decentralization of information making it more secure, verifiable, transparent and reliable.


Author(s):  
Peter McCormick

AbstractGiven the visibility and obvious importance of judicial power in the age of the Charter, it is important to develop the conceptual vocabulary for desribing and assessing this power. One such concept that has been applied to the study of appeal courts in the United States and Great Britain is “party capability”, a theory which suggests that different types of litigant will enjoy different levels of success as both appellant and respondent. Using a data base derived from the reported decisions of the provincial courts of appeal for the second and seventh year of each decade since the 1920s, this article applies party capability theory to the performance of the highest courts of the ten provinces; comparisons are attempted across regions and across time periods, as well as with the findings of similar studies of American and British courts.


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