scholarly journals Power Regulation Characteristics of Instantaneous Current Vector Control High-Frequency Resonant ZCS Inverter

2012 ◽  
Vol 37 (0) ◽  
pp. 245-245
Author(s):  
Chikanori Takami ◽  
Tomokazu Mishima ◽  
Mutsuo Nakaoka
Keyword(s):  
Vector Control ◽  
High Frequency ◽  
Current Vector ◽  
Power Regulation ◽  
Instantaneous Current

scholarly journals Additional evidence on the efficacy of different Akirin vaccines assessed on Anopheles arabiensis (Diptera: Culicidae)

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Blaženka D. Letinić ◽  
Marinela Contreras ◽  
Yael Dahan-Moss ◽  
Ingrid Linnekugel ◽  
José de la Fuente ◽  
...  
Keyword(s):  
Vector Control ◽  
Aedes Albopictus ◽  
Malaria Vector ◽  
Vaccine Efficacy ◽  
Anopheles Arabiensis ◽  
Vaccine Development ◽  
Target Antigen ◽  
Control Methods ◽  
Protective Response ◽  
Current Vector

Abstract Background Anopheles arabiensis is an opportunistic malaria vector that rests and feeds outdoors, circumventing current indoor vector control methods. Furthermore, this vector will readily feed on both animals and humans. Targeting this vector while feeding on animals can provide an additional intervention for the current vector control activities. Previous results have displayed the efficacy of using Subolesin/Akirin ortholog vaccines for the control of multiple ectoparasite infestations. This made Akirin a potential antigen for vaccine development against An. arabiensis. Methods The efficacy of three antigens, namely recombinant Akirin from An. arabiensis, recombinant Akirin from Aedes albopictus, and recombinant Q38 (Akirin/Subolesin chimera) were evaluated as novel interventions for An. arabiensis vector control. Immunisation trials were conducted based on the concept that mosquitoes feeding on vaccinated balb/c mice would ingest antibodies specific to the target antigen. The antibodies would interact with the target antigen in the arthropod vector, subsequently disrupting its function. Results All three antigens successfully reduced An. arabiensis survival and reproductive capacities, with a vaccine efficacy of 68–73%. Conclusions These results were the first to show that hosts vaccinated with recombinant Akirin vaccines could develop a protective response against this outdoor malaria transmission vector, thus providing a step towards the development of a novel intervention for An. arabiensis vector control. Graphic Abstract

scholarly journals Nextgen Vector Surveillance Tools: sensitive, specific, cost-effective and epidemiologically relevant

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Robert Farlow ◽  
Tanya L. Russell ◽  
Thomas R. Burkot
Keyword(s):  
Decision Making ◽  
Vector Control ◽  
Malaria Control ◽  
Cost Effective ◽  
Effective Control ◽  
Next Generation ◽  
Vector Data ◽  
Vector Surveillance ◽  
Current Vector ◽  
Control Programmes

Abstract Background Vector surveillance provides critical data for decision-making to ensure that malaria control programmes remain effective and responsive to any threats to a successful control and elimination programme. The quality and quantity of data collected is dependent on the sampling tools and laboratory techniques used which may lack the sensitivity required to collect relevant data for decision-making. Here, 40 vector control experts were interviewed to assess the benefits and limitations of the current vector surveillance tools and techniques. In addition, experts shared ideas on “blue sky” indicators which encompassed ideas for novel methods to monitor presently used indicators, or to measure novel vector behaviours not presently measured. Algorithms for deploying surveillance tools and priorities for understanding vector behaviours are also needed for collecting and interpreting vector data. Results The available tools for sampling and analysing vectors are often hampered by high labour and resource requirements (human and supplies) coupled with high outlay and operating costs and variable tool performance across species and geographic regions. The next generation of surveillance tools needs to address the limitations of present tools by being more sensitive, specific and less costly to deploy to enable the collection and use of epidemiologically relevant vector data to facilitate more proactive vector control guidance. Ideas and attributes for Target Product Profiles (TPPs) generated from this analysis provide targets for research and funding to develop next generation tools. Conclusions More efficient surveillance tools and a more complete understanding of vector behaviours and populations will provide a basis for more cost effective and successful malaria control. Understanding the vectors’ behaviours will allow interventions to be deployed that target vulnerabilities in vector behaviours and thus enable more effective control. Through defining the strengths and weaknesses of the current vector surveillance methods, a foundation and initial framework was provided to define the TPPs for the next generation of vector surveillance methods. The draft TTPs presented here aim to ensure that the next generation tools and technologies are not encumbered by the limitations of present surveillance methods and can be readily deployed in low resource settings.

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