Contrast-induced acute kidney injury in renal transplant recipients after cardiac catheterization

2009 ◽  
Vol 71 (06) ◽  
pp. 687-696 ◽  
Author(s):  
V. Agrawal ◽  
A. Swami ◽  
R. Kosuri ◽  
M. AlSabbagh ◽  
M. Agarwal ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Transplant ◽  
Cardiac Catheterization ◽  
Kidney Injury ◽  
Renal Transplant Recipients ◽  
Transplant Recipients

scholarly journals FP247The urinary microbiome during acute kidney injury in renal transplant recipients versus non-transplant recipients

2019 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Daniela Knafl ◽  
Wolfgang Winnicki ◽  
Alexander Zimprich ◽  
Christoph Hotzy ◽  
Wolfgang Barousch ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Transplant ◽  
Kidney Injury ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Urinary Microbiome

scholarly journals Acute kidney injury in renal transplant recipients undergoing cardiac surgery

2020 ◽  
Vol 36 (1) ◽  
pp. 185-196
Author(s):  
Gregory L Hundemer ◽  
Anand Srivastava ◽  
Kirolos A Jacob ◽  
Neeraja Krishnasamudram ◽  
Salman Ahmed ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Cardiac Surgery ◽  
Risk Factor ◽  
Renal Transplant ◽  
Kidney Disease ◽  
Kidney Injury ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Trough Levels

Abstract Background Acute kidney injury (AKI) is a key risk factor for chronic kidney disease in the general population, but has not been investigated in detail among renal transplant recipients (RTRs). We investigated the incidence, severity and risk factors for AKI following cardiac surgery among RTRs compared with non-RTRs with otherwise similar clinical characteristics. Methods We conducted a retrospective cohort study of RTRs (n = 83) and non-RTRs (n = 83) who underwent cardiac surgery at two major academic medical centers. Non-RTRs were matched 1:1 to RTRs by age, preoperative (preop) estimated glomerular filtration rate and type of cardiac surgery. We defined AKI according to Kidney Disease: Improving Global Outcomes criteria. Results RTRs had a higher rate of AKI following cardiac surgery compared with non-RTRs [46% versus 28%; adjusted odds ratio 2.77 (95% confidence interval 1.36–5.64)]. Among RTRs, deceased donor (DD) versus living donor (LD) status, as well as higher versus lower preop calcineurin inhibitor (CNI) trough levels, were associated with higher rates of AKI (57% versus 33% among DD-RTRs versus LD-RTRs; P = 0.047; 73% versus 36% among RTRs with higher versus lower CNI trough levels, P = 0.02). The combination of both risk factors (DD status and higher CNI trough level) had an additive effect (88% AKI incidence among patients with both risk factors versus 25% incidence among RTRs with neither risk factor, P = 0.004). Conclusions RTRs have a higher risk of AKI following cardiac surgery compared with non-RTRs with otherwise similar characteristics. Among RTRs, DD-RTRs and those with higher preop CNI trough levels are at the highest risk.

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