Bacterial endocarditis manifesting as autoimmune pulmonary renal syndrome: ANCA-associated lung hemorrhage and pauci-immune crescentic glomerulonephritis

2018 ◽  
Vol 90 (6) ◽  
pp. 431-433 ◽  
Author(s):  
Samer Mohandes ◽  
Anjali Satoskar ◽  
Lee Hebert ◽  
Isabelle Ayoub
Keyword(s):  
Crescentic Glomerulonephritis ◽  
Bacterial Endocarditis ◽  
Pulmonary Renal Syndrome ◽  
Lung Hemorrhage

scholarly journals Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Tariq Javed ◽  
Parag Vohra
Keyword(s):  
Renal Failure ◽  
Renal Biopsy ◽  
Recurrence Rate ◽  
Crescentic Glomerulonephritis ◽  
Diagnosis And Treatment ◽  
Atypical Presentation ◽  
Long Term Follow Up ◽  
Pulmonary Renal Syndrome

We are presenting a case of renal failure with anti-GBM and p-ANCA antibodies positive. Patients with dual antibodies are considered to be a vasculitis-variant of anti-GBM antibody nephritis. These patients may have atypical presentation and it may delay diagnosis and treatment. Recurrence rate is higher in these patients. We reviewed the literature of cases and studies on cresenteric glomerulonephritis with anti-GBM and p-ANCA positive patients. We recommend that patients suspected with pulmonary-renal syndrome should be checked for anti-GBM and p-ANCA antibodies, should undergo renal biopsy and should should have close long term follow up to watch for recurrence.

Diffuse crescentic glomerulonephritis in bacterial endocarditis

2001 ◽  
Vol 16 (5) ◽  
pp. 423-428 ◽  
Author(s):  
Sujatha Kannan ◽  
T. K. Mattoo
Keyword(s):  
Crescentic Glomerulonephritis ◽  
Bacterial Endocarditis

scholarly journals Fatal Pulmonary-renal Syndrome Manifested with Immune Complex Crescentic Glomerulonephritis in a Patient with MPO-ANCA Seropositivity

2001 ◽  
Vol 42 (4) ◽  
pp. 425 ◽  
Author(s):  
Joon Ho Song ◽  
Kyong Joo Lee ◽  
Seoung Woo Lee ◽  
Jee Young Han ◽  
Moon Jae Kim
Keyword(s):  
Immune Complex ◽  
Crescentic Glomerulonephritis ◽  
Pulmonary Renal Syndrome

BACTERIAL ENDOCARDITIS ASSOCIATED WITH CRESCENTIC GLOMERULONEPHRITIS IN A KIDNEY TRANSPLANT PATIENT

1998 ◽  
Vol 66 (5) ◽  
pp. 653-654 ◽  
Author(s):  
Lionel Ades ◽  
Kodzo Akposso ◽  
Marie-Alyette Costa de Beauregard ◽  
Jean-Philippe Haymann ◽  
B??atrice Mougenot ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Transplant Patient ◽  
Crescentic Glomerulonephritis ◽  
Bacterial Endocarditis ◽  
Kidney Transplant Patient

scholarly journals Necrotizing Crescentic Glomerulonephritis Complicating Bivalvular Bacterial Endocarditis

Cureus ◽  
2018 ◽  
Author(s):  
Arsalan Talib Hashmi ◽  
Muhammad Khalid ◽  
Husnain Waseem ◽  
Asiya Batool ◽  
Jignesh Patel ◽  
...  
Keyword(s):  
Crescentic Glomerulonephritis ◽  
Bacterial Endocarditis ◽  
Necrotizing Crescentic Glomerulonephritis

scholarly journals Rapidly progressive antineutrophil cytoplasm antibodies associated with pulmonary-renal syndrome in a 10-year-old girl

2001 ◽  
Vol 119 (1) ◽  
pp. 29-32 ◽  
Author(s):  
Fermin Blanco Filho ◽  
Luci Carla Ernesto ◽  
Mônica Assis Rosa ◽  
Luis Antônio Stuginski ◽  
Eliana Regina Zlochevsky ◽  
...  
Keyword(s):  
White Blood Cells ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Pulmonary Hemorrhage ◽  
Signs And Symptoms ◽  
Antigen Specificity ◽  
Primary Health Center ◽  
Pulmonary Renal Syndrome ◽  
Lung Hemorrhage ◽  
Clinical Signs And Symptoms

CONTEXT: The term pulmonary-renal syndrome has been used frequently to describe the clinical manifestations of a great number of diseases in which pulmonary hemorrhage and glomerulonephritis coexist. The classic example of this type of vasculitis is Goodpasture´s syndrome, a term used to describe the association of pulmonary hemorrhage, glomerulonephritis and the presence of circulating antiglomerular basement membrane antibodies (anti-GBM). Among the several types of systemic vasculitides that can present clinical manifestations of the pulmonary-renal syndrome, we focus the discussion on two types more frequently associated with antineutrophil cytoplasm antibodies (ANCA), microscopic polyangiitis and Wegener´s granulomatosis, concerning a 10 year old girl with clinical signs and symptoms of pulmonary-renal syndrome, with positive ANCA and rapidly progressive evolution. CASE REPORT: We describe the case of a 10-year-old girl referred to our hospital for evaluation of profound anemia detected in a primary health center. Five days before entry she had experienced malaise, pallor and began to cough up blood-tinged sputum that was at first attributed to dental bleeding. She was admitted to the infirmary with hemoglobin = 4 mg/dL, hematocrit = 14%, platelets = 260,000, white blood cells = 8300, 74% segmented, 4% eosinophils, 19% lymphocytes and 3% monocytes. Radiographs of the chest revealed bilateral diffuse interstitial alveolar infiltrates. There was progressive worsening of cough and respiratory distress during the admission day, when she began to cough up large quantities of blood and hematuria was noted. There was rapid and progressive loss of renal function and massive lung hemorrhage. The antineutrophil cytoplasm antibody (ANCA) test with antigen specificity for myeloperoxidase (anti-MPO) was positive and the circulating anti-GBM showed an indeterminate result.

scholarly journals Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ramy Magdy Hanna ◽  
Eduardo Lopez ◽  
James Wilson
Keyword(s):  
Ventricular Tachycardia ◽  
Aortic Valve Disease ◽  
Crescentic Glomerulonephritis ◽  
Granulomatosis With Polyangiitis ◽  
Acute Myocarditis ◽  
Reactive Thrombocytosis ◽  
Renal Lesions ◽  
Pulmonary Manifestations ◽  
Pulmonary Renal Syndrome ◽  
Multiple Episodes

Granulomatosis with polyangiitis (GPA), previously known as Wegener’s granulomatosis, is a pulmonary-renal syndrome affecting small and medium sized blood vessels. The disease has a prevalence in studies ranging from 3 to 15.7 cases per 100,000, with a noted increasing incidence and prevalence in more recent studies. Pulmonary manifestations include hemorrhage, lung cavitary lesions, and pulmonary fibrosis. Within the kidney, GPA is known to cause rapidly progressive pauci-immune crescentic glomerulonephritis. Rare and severe cardiovascular manifestations include pericarditis, arrhythmias, myocarditis, and aortic valve disease. Our patient is a 43-year-old female with typical pulmonary and renal lesions from GPA and also acute myocarditis, multiple episodes of ventricular tachycardia, and a severe reactive thrombocytosis.

INTRINSIC RENAL CELL DERIVED IL‐12 IS AN EFFECTOR OF RENAL GLOMERULAR INJURY IN CRESCENTIC GLOMERULONEPHRITIS

Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A98-A98
Author(s):  
Timoshanko Jr ◽  
Kitching Ar ◽  
Holdsworth Sr ◽  
Tipping PG.
Keyword(s):  
Renal Cell ◽  
Crescentic Glomerulonephritis ◽  
Glomerular Injury
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