scholarly journals Necrotizing Crescentic Glomerulonephritis Complicating Bivalvular Bacterial Endocarditis

Cureus ◽  
2018 ◽  
Author(s):  
Arsalan Talib Hashmi ◽  
Muhammad Khalid ◽  
Husnain Waseem ◽  
Asiya Batool ◽  
Jignesh Patel ◽  
...  
Keyword(s):  
Crescentic Glomerulonephritis ◽  
Bacterial Endocarditis ◽  
Necrotizing Crescentic Glomerulonephritis

scholarly journals Lung adenocarcinoma and sequential antineutrophil cytoplasmic antibody-associated vasculitis: a case report

2021 ◽  
Vol 49 (2) ◽  
pp. 030006052199331
Author(s):  
Chun-Yang Zhang ◽  
Ran Miao ◽  
Wei Li ◽  
Hao-Yong Ning ◽  
Xiang-En Meng ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Histological Examination ◽  
Crescentic Glomerulonephritis ◽  
Elevated Serum ◽  
Pulmonary Nodules ◽  
Antineutrophil Cytoplasmic Antibody ◽  
Necrotizing Crescentic Glomerulonephritis ◽  
Transthoracic Biopsy ◽  
Nasal Inflammation ◽  
The Relationship

The relationship between antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and lung cancer remains unclear. A 66-year-old man presented with pulmonary nodules. Histological examination of a specimen from computed tomography-guided percutaneous transthoracic biopsy revealed adenocarcinoma. The patient was treated using cryoablation and systemic chemotherapy. Sixteen months later, the patient presented with fever, nasal inflammation, recurrent lung lesions, elevated serum creatinine levels, and high levels of ANCA. Histological examination of a specimen from ultrasound-guided percutaneous renal biopsy revealed pauci-immune necrotizing crescentic glomerulonephritis. The patient responded to treatment, but granulomatosis with polyangiitis recurred and he later died. This case highlights the possibility of sequential AAV with lung cancer. Although this is relatively rare, further research is needed to better understand the association or pathophysiological link between lung cancer and AAV.

Two cases of necrotizing crescentic glomerulonephritis with skin lesions

1998 ◽  
Vol 8 (1) ◽  
pp. 79-87
Author(s):  
Hidekazu Moriya ◽  
Iwao Nakabayashi ◽  
Junichirou Nishiyama ◽  
Aki Ishida ◽  
Keiji Tazawa ◽  
...  
Keyword(s):  
Crescentic Glomerulonephritis ◽  
Skin Lesions ◽  
Necrotizing Crescentic Glomerulonephritis

scholarly journals Antineutrophil Cytoplasmic Autoantibody—Associated Glomerulonephritis in Children

2001 ◽  
Vol 12 (7) ◽  
pp. 1493-1500 ◽  
Author(s):  
MOTOSHI HATTORI ◽  
HIDEAKI KURAYAMA ◽  
YASUSHI KOITABASHI
Keyword(s):  
Renal Function ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Crescentic Glomerulonephritis ◽  
Small Sample ◽  
Renal Outcome ◽  
Necrotizing Crescentic Glomerulonephritis ◽  
Antineutrophil Cytoplasmic Autoantibody ◽  
Stage Renal Disease ◽  
End Stage

Abstract. A retrospective investigation was conducted by members of the Japanese Society for Pediatric Nephrology from 1990 to 1997 to define the clinical features and outcome of antineutrophil cytoplasmic autoantibody (ANCA)-associated glomerulonephritis in children. Thirty-four ANCA-seropositive Japanese pediatric patients with biopsy-proven pauci-immune necrotizing crescentic glomerulonephritis were identified. Of these, 3 cases associated with Wegener's granulomatosis were excluded because of the small sample size. Among the 31 patients studied, 10 had a diagnosis of necrotizing crescentic glomerulonephritis alone and 21 had microscopic polyangiitis. Females predominated (87%), and the median age at onset was 12 yr. Twenty-six patients received treatment with cyclophosphamide and corticosteroids, and five patients received treatment with corticosteroids alone; 84% of patients achieved remission, and 39% of responders relapsed in a median of 24 mo. ANCA titers correlated with response to treatment and disease activity, with some exceptions. Patients were followed for a median of 42 mo (range, 3 to 96 mo). Nine of 31 patients (29.0%) progressed to end-stage renal disease, 6 (19.4%) had reduced renal function, and 15 (48.4%) had normal renal function at the last observation. One patient (3.2%) died from cytomegalovirus infection 3 mo after initiation of therapy. Life-table analysis showed 75% renal survival at 39 mo. Patients who subsequently developed end-stage renal disease (n= 9) had significantly higher average peak serum creatinine levels and more chronic pathologic lesions at diagnosis compared with patients with favorable renal outcome (n= 15). In conclusion, our clinical experience suggests that the clinical disease spectrum of ANCA-associated glomerulonephritis is similar in pediatric and adult patients, but there is a female predominance in children.

scholarly journals Elastase-ANCA-associated idiopathic necrotizing crescentic glomerulonephritis--a report of three cases

2007 ◽  
Vol 22 (7) ◽  
pp. 2068-2071 ◽  
Author(s):  
A. Seidowsky ◽  
M. Hoffmann ◽  
S. Ruben-Duval ◽  
R. Mesbah ◽  
E. Masy ◽  
...  
Keyword(s):  
Crescentic Glomerulonephritis ◽  
Necrotizing Crescentic Glomerulonephritis

Two cases of necrotizing crescentic glomerulonephritis with skin lesions

1998 ◽  
Vol 8 (1) ◽  
pp. 79-87
Author(s):  
Hidekazu Moriya ◽  
Iwao Nakabayashi ◽  
Junichirou Nishiyama ◽  
Aki Ishida ◽  
Keiji Tazawa ◽  
...  
Keyword(s):  
Crescentic Glomerulonephritis ◽  
Skin Lesions ◽  
Necrotizing Crescentic Glomerulonephritis
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